{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T12:34:58Z","timestamp":1774874098924,"version":"3.50.1"},"reference-count":18,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>An nm-thickness composite gold thin film consisting of gold nanoparticles and polyelectrolytes is fabricated through ionic self-assembled multilayers (ISAM) technique and is deposited on end-faces of optical fibers to construct localized surface plasmon resonance (LSPR) fiber probes. We demonstrate that the LSPR spectrum induced by ISAM gold films can be fine-tuned through the ISAM procedure. We investigate variations of reflection spectra of the probe with respect to the layer-by-layer adsorption of ISAMs onto end-faces of fibers, and study the spectral variation mechanism. Finally, we demonstrated using this fiber probe to detect the biotin-streptavidin bioconjugate pair. ISAM adsorbed on optical fibers potentially provides a simple, fast, robust, and low-cost, platform for LSPR biosensing applications.<\/jats:p>","DOI":"10.3390\/s100706477","type":"journal-article","created":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T10:01:43Z","timestamp":1277978503000},"page":"6477-6487","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles"],"prefix":"10.3390","volume":"10","author":[{"given":"Miao","family":"Wan","sequence":"first","affiliation":[{"name":"Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA"},{"name":"College of Math and Physics, China University of Geoscience, Wuhan 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pengfei","family":"Luo","sequence":"additional","affiliation":[{"name":"Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiayi","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Electrical & Computer Engineering, Texas A&M University, College Station, Texas 77844, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiong","family":"Xing","sequence":"additional","affiliation":[{"name":"Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyong","family":"Wang","sequence":"additional","affiliation":[{"name":"Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen T. C.","family":"Wong","sequence":"additional","affiliation":[{"name":"Bioengineering and Bioinformatics Program, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, Texas 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2010,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1002\/adma.200400271","article-title":"Exploitation of localized surface plasmon resonance","volume":"16","author":"Hutter","year":"2004","journal-title":"Advan. Mater"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1021\/jp026731y","article-title":"The optical properties of metal nanoparticles: The influence of size, shape, and dielectric environment","volume":"107","author":"Kelly","year":"2003","journal-title":"J. Phys. Chem. 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