{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T22:25:18Z","timestamp":1771626318069,"version":"3.50.1"},"reference-count":42,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2010,12,2]],"date-time":"2010-12-02T00:00:00Z","timestamp":1291248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The specific advantages of ultra-wideband electromagnetic remote sensing (UWB radar) make it a particularly attractive technique for biomedical applications. We partially review our activities in utilizing this novel approach for the benefit of high and ultra-high field magnetic resonance imaging (MRI) and other applications, e.g., for intensive care medicine and biomedical research. We could show that our approach is beneficial for applications like motion tracking for high resolution brain imaging due to the non-contact acquisition of involuntary head motions with high spatial resolution, navigation for cardiac MRI due to our interpretation of the detected physiological mechanical contraction of the heart muscle and for MR safety, since we have investigated the influence of high static magnetic fields on myocardial mechanics. From our findings we could conclude, that UWB radar can serve as a navigator technique for high and ultra-high field magnetic resonance imaging and can be beneficial preserving the high resolution capability of this imaging modality. Furthermore it can potentially be used to support standard ECG analysis by complementary information where sole ECG analysis fails. Further analytical investigations have proven the feasibility of this method for intracranial displacements detection and the rendition of a tumour\u2019s contrast agent based perfusion dynamic. Beside these analytical approaches we have carried out FDTD simulations of a complex arrangement mimicking the illumination of a human torso model incorporating the geometry of the antennas applied.<\/jats:p>","DOI":"10.3390\/s101210778","type":"journal-article","created":{"date-parts":[[2010,12,2]],"date-time":"2010-12-02T12:49:51Z","timestamp":1291294191000},"page":"10778-10802","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Ultra-Wideband Sensors for Improved Magnetic Resonance Imaging, Cardiovascular Monitoring and Tumour Diagnostics"],"prefix":"10.3390","volume":"10","author":[{"given":"Florian","family":"Thiel","sequence":"first","affiliation":[{"name":"Physikalisch-Technische Bundesanstalt (PTB), Abbe-Str. 2-12, 10587 Berlin, Germany"}]},{"given":"Olaf","family":"Kosch","sequence":"additional","affiliation":[{"name":"Physikalisch-Technische Bundesanstalt (PTB), Abbe-Str. 2-12, 10587 Berlin, Germany"}]},{"given":"Frank","family":"Seifert","sequence":"additional","affiliation":[{"name":"Physikalisch-Technische Bundesanstalt (PTB), Abbe-Str. 2-12, 10587 Berlin, Germany"}]}],"member":"1968","published-online":{"date-parts":[[2010,12,2]]},"reference":[{"key":"ref_1","unstructured":"Droitcour, AD (2006). Non-Contact Measurement of Heart and Respiration Rates with a Single-Chip Microwave Doppler Radar, Stanford University. PhD Thesis."},{"key":"ref_2","unstructured":"Hunt, S, Roseiro, A, and Siegel, M Signal Processing for a Non-Invasive Microwave Heart Rate Estimator. New Orleans, LA, USA."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0753-3322(05)80030-7","article-title":"A Novel Apparatus for Non-Contact Measurement of Heart Rate Variability: A System to Prevent Secondary Exposure of Medical Personnel to Toxic Materials under Biochemical Hazard Conditions. In Monitoring Sepsis or in Predicting Multiple Organ Dysfunction Syndrome","volume":"59","author":"Matsui","year":"2005","journal-title":"Biomed Pharmacother"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Kim, HJ, Kim, KH, Hong, YS, and Choi, JJ (2007). Measurement of Human Heartbeat and Respiration Signals Using Phase Detection Radar. Rev Sci Instrum, 78. doi: 10.1063\/1.2798937.","DOI":"10.1063\/1.2798937"},{"key":"ref_5","unstructured":"Yin, Y, Qian, J, Lu, J, and Huang, Y On the Operation Mechanism of the Microwave Sensor for Measuring Human Heartbeats and Respirations. Toronto, ON, Canada."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1114\/1.1553452","article-title":"Microwave Tomography for Detection\/Imaging of Myocardial Infarction. I. Excised Canine Hearts","volume":"31","author":"Semenov","year":"2003","journal-title":"Ann Biomed Eng"},{"key":"ref_7","unstructured":"Muehlsteff, J, Thijs, J, Pinter, R, Morren, G, and Muesch, G A Handheld Device for Simultaneous Detection of Electrical and Mechanical Cardio-Vascular Activities with Synchronized ECG and CW-Doppler Radar. Lyon France."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1109\/TAP.2010.2046848","article-title":"Ultra-Wideband Antennas for Magnetic Resonance Imaging Navigator Techniques","volume":"58","author":"Schwarz","year":"2010","journal-title":"IEEE Trans. Ant. Prop"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Thiel, F, Hein, M, Schwarz, U, Sachs, J, and Seifert, F (2009). Combining Magnetic Resonance Imaging and Ultra-wideband Radar: A New Concept for Multimodal Biomedical Imaging. Rev Sci Instrum, 80. doi: 10.1063\/1.3053242.","DOI":"10.1063\/1.3065095"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Thiel, F, Hein, M, Sachs, J, Schwarz, U, and Seifert, F (2008). Physiological Signatures Monitored by Ultra-wideband-radar Validated by Magnetic Resonance Imaging, ICUWB.","DOI":"10.1109\/ICUWB.2008.4653295"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1088\/0957-0233\/18\/4\/016","article-title":"Liquid and Moisture Sensing by Ultra-wideband Pseudo-Noise Sequence Signals","volume":"18","author":"Sachs","year":"2007","journal-title":"Meas Sci Technol"},{"key":"ref_12","unstructured":"Sachs, J, Dvoracek, J, Schneider, A, Friedrich, J, and Zetik, R Ultra-Wideband Methods Applied for Moisture and Liquid Sensing. Weimar, Germany."},{"key":"ref_13","unstructured":"Daniels, DJ (2004). IEE Radar, Sonar, Navigation and Avionics Series 15, [2nd ed.]."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1109\/TGRS.2004.834589","article-title":"Noise Radar using Random Phase and Frequency Modulation","volume":"42","author":"Axelsson","year":"2004","journal-title":"IEEE Trans Geosci Remote Sens"},{"key":"ref_15","unstructured":"Sachs, J, and Peyerl, P A New Principle for Sensor-Array-Application. Venice, Italy."},{"key":"ref_16","unstructured":"Ziemer, RE, Peterson, RL, and Borth, DE (1995). Introduction to Spread Spectrum Communications, Prentice-Hall."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1109\/TAP.2010.2046848","article-title":"Ultra-Wideband Antennas for Magnetic Resonance Imaging Navigator Techniques","volume":"58","author":"Schwarz","year":"2010","journal-title":"IEEE Trans Ant Prop"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1148\/radiology.163.3.3575734","article-title":"Human Brain Motion and Cerebrospinal Fluid Circulation Demonstrated with MR Velocity Imaging","volume":"163","author":"Feinberg","year":"1987","journal-title":"Radiology"},{"key":"ref_19","unstructured":"The Visible Human Project Available online: http:\/\/www.nlm.nih.gov\/research\/visible\/visible_human.html (accessed on 10 November 2010)."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Thiel, F, and Seifert, F (2009). Non-invasive Probing of the Human Body with Electromagnetic Pulses: Modelling of the Signal Path. J Appl Phys, 105. doi: 10.1063\/1.3077299.","DOI":"10.1063\/1.3077299"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1088\/0031-9155\/41\/11\/001","article-title":"The Dielectric Properties of Biological Tissues I\u2013III","volume":"41","author":"Gabriel","year":"1996","journal-title":"Phys Med Biol"},{"key":"ref_22","unstructured":"Orphanidis, SJ Available online: http:\/\/www.ece.rutgers.edu\/~orfanidi\/ewa\/ (accessed on 25 November 2010)."},{"key":"ref_23","unstructured":"H\u00e4m\u00e4l\u00e4inen, M (2006). University of Oulu."},{"key":"ref_24","unstructured":"Thiel, F, Kosch, O, and Seifert, F Intracranial Pulsation Detected by Ultra-wideband Radar: Detectability Analysis Using Synthetic Signals. Barcelona, Spain."},{"key":"ref_25","unstructured":"Kosch, O, Thiel, F, Yan, DD, and Seifert, F Discrimination of Respirative and Cardiac Displacements from Ultra-wideband Radar Data. Berlin, Germany."},{"key":"ref_26","first-page":"269","article-title":"Characterization of the Magneto-hydrodynamic Effect as a Signal from the Surface Electrocardiogram during Cardiac Magnetic Resonance Imaging","volume":"33","author":"Nijm","year":"2006","journal-title":"Comput Cardiol"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Thiel, F, Kreiseler, D, and Seifert, F (2009). Non-Contact Detection of Myocardium's Mechanical Activity by Ultra-Wideband Rf-Radar and Interpretation Applying Electrocardiography. Rev Sci Instrum, 80. doi: 10.1063\/1.3238506.","DOI":"10.1063\/1.3238506"},{"key":"ref_28","unstructured":"Droste, C, and von Planta, M (1993). Memorix: Konstanten der klinischen Medizin, VCH Verlag. [3rd ed]."},{"key":"ref_29","unstructured":"Li, X, Hagness, SC, Van Veen, BD, and van der Weide, D (2003). Experimental Investigation of Microwave Imaging via Space-Time Beamforming for Breast Cancer Detection, IMS."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"074009","DOI":"10.1088\/0266-5611\/26\/7\/074009","article-title":"Contrast-Enhanced Microwave Imaging of Breast Tumors: A Computational Study Using 3D Realistic Numerical Phantoms","volume":"26","author":"Shea","year":"2010","journal-title":"Inverse Problems"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1109\/TMI.2008.2008959","article-title":"Three-Dimensional Microwave Breast Imaging: Dispersive Dielectric Properties Estimation Using Patient-Specific Basis Functions","volume":"28","author":"Winters","year":"2009","journal-title":"IEEE Trans. Med. Imag."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1109\/TBME.2008.925700","article-title":"Electromagnetic Spectroscopy of Normal Breast Tissue Specimens Obtained from Reduction Surgeries: Comparison of Optical and Microwave Properties","volume":"55","author":"Lazebnik","year":"2008","journal-title":"IEEE Trans Biomed Eng"},{"key":"ref_33","first-page":"1357","article-title":"A Target Shape Estimation Algorithm for Pulse Radar Systems Based on Boundary Scattering Transform","volume":"E87-B","author":"Sakamoto","year":"2004","journal-title":"IEICE Trans Commun"},{"key":"ref_34","unstructured":"Helbig, M, Geyer, C, Hein, M, Herrmann, R, Hilger, I, Schwarz, U, and Sachs, J (2009). IUPESM."},{"key":"ref_35","unstructured":"Thiel, F, and Seifert, F Reflection Coefficient of the Human Thorax: Sensitivity to Intrathoracic Displacements and Incorporation into an Ultra-Wideband Channel. Berlin, Germany."},{"key":"ref_36","unstructured":"Thiel, F, Kosch, O, and Seifert, F Contrast Agent Based Tumour Detection by Ultra-Wideband Radar: A Model Approach. Barcelona, Spain."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"N23","DOI":"10.1088\/0031-9155\/55\/2\/N01","article-title":"The Virtual Family\u2014Development of Surface-Based Anatomical Models of two Adults and two Children for Dosimetric Simulations","volume":"55","author":"Christ","year":"2010","journal-title":"Phys Med Biol"},{"key":"ref_38","first-page":"34","article-title":"Physiological Signatures Reconstructed from a dynamic Human Model Exposed to Ultra-Wideband Microwave Signals","volume":"64","author":"Thiel","year":"2010","journal-title":"Frequenz J RF-Eng Telecom"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"145","DOI":"10.2165\/00002018-200427030-00001","article-title":"Pharmacogenetic Aspects of Drug-Induced Torsade de Pointes: Potential Tool for Improving Clinical Drug Development and Prescribing","volume":"27","author":"Shah","year":"2004","journal-title":"Drug Saf"},{"key":"ref_40","unstructured":"Safety Pharmacology Studies for Assessing the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals Available online: http:\/\/www.ich.org\/MediaServer.jser?@_ID_505&@_MODE_GLB\/ (accessed on 30 October 2010)."},{"key":"ref_41","unstructured":"Steinhoff, U, Knappe-Gr\u00fcneberg, S, Schnabel, A, Thiel, F, Schurig, T, Bader, M, and Koch, H MCG as a Tool for Drug Safety Testing and Knock-Out Model Animal Studies. Boston, MA, USA."},{"key":"ref_42","unstructured":"Note: The measurement protocol had been approved by the local ethics committee and written informed consent was obtained from each participant according to the Declaration of Helsinki."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/10\/12\/10778\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T22:03:59Z","timestamp":1760220239000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/10\/12\/10778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12,2]]},"references-count":42,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2010,12]]}},"alternative-id":["s101210778"],"URL":"https:\/\/doi.org\/10.3390\/s101210778","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,12,2]]}}}