{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:12:03Z","timestamp":1771333923303,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2010,12,7]],"date-time":"2010-12-07T00:00:00Z","timestamp":1291680000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this report, we present a new method for visual detection of Pb2+. Gold nanoparticles (Au-NPs) were synthesized in one step at room temperature, using gallic acid (GA) as reducer and stabilizer. Pb2+ is added during the gold nanoparticle formation. Analysis of Pb2+ is conducted by a dual strategy, namely, colorimetry and spectrometry. During Au-NPs synthesis, addition of Pb2+ would lead to formation of Pb-GA complex, which can induce the aggregation of newly-formed small unstable gold nanoclusters. Consequently, colorimetric detection of trace Pb2+ can be realized. As the Pb2+ concentration increases, the color turns from red-wine to purple, and finally blue. This method offers a sensitive linear correlation between the shift of the absorption band (\u0394\u03bb) and logarithm of Pb2+ concentration ranging from 5.0 \u00d7 10\u22128 to 1.0 \u00d7 10\u22126 M with a linear fit coefficient of 0.998, and a high selectivity for Pb2+ detection with a low detection limit down to 2.5 \u00d7 10\u22128 M.<\/jats:p>","DOI":"10.3390\/s101211144","type":"journal-article","created":{"date-parts":[[2010,12,7]],"date-time":"2010-12-07T10:59:20Z","timestamp":1291719560000},"page":"11144-11155","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Colorimetric Assay for Determination of Lead (II) Based on Its Incorporation into Gold Nanoparticles during Their Synthesis"],"prefix":"10.3390","volume":"10","author":[{"given":"Nan","family":"Ding","sequence":"first","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Cao","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yimin","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lixi","family":"Zeng","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujian","family":"He","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, 19A YuQuan Road, Beijing 100049, China"},{"name":"State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaixiang","family":"Xiang","sequence":"additional","affiliation":[{"name":"Huaihua Medical College, Hunan, 418000, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guangwei","family":"Wang","sequence":"additional","affiliation":[{"name":"Medical College, Hunan Normal University, Changsha, Hunan 410006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2010,12,7]]},"reference":[{"key":"ref_1","unstructured":"Available online: http:\/\/www.osha.gov\/SLTC\/lead\/index.html (accessed on 30 May 2008)."},{"key":"ref_2","first-page":"56","article-title":"Lead poisoning","volume":"13","author":"Rizescu","year":"2008","journal-title":"Metal Int"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"9316","DOI":"10.1021\/ja063029x","article-title":"A selective fluorescent sensor for detecting lead in living cells","volume":"128","author":"He","year":"2006","journal-title":"J Am Chem Soc"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.snb.2007.10.041","article-title":"An organically modified sol-gel membrane for detection of lead ion by using 2-hydroxy-1-naphthaldehydene-8-aminoquinoline as fluorescence probe","volume":"130","author":"Guo","year":"2008","journal-title":"Sens Actuat 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