{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T01:58:56Z","timestamp":1769824736542,"version":"3.49.0"},"reference-count":46,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2011,5,31]],"date-time":"2011-05-31T00:00:00Z","timestamp":1306800000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A series of dopant-type polyaniline-polyacrylic acid composite (PAn-PAA) films with porous structures were prepared and developed for an enzyme-free hydrogen peroxide (H2O2) sensor. The composite films were highly electroactive in a neutral environment as compared to polyaniline (PAn). In addition, the carboxyl group of the PAA was found to react with H2O2 to form peroxy acid groups, and the peroxy acid could further oxidize the imine structure of PAn to form N-oxides. The N-oxides reverted to their original form via electrochemical reduction and increased the reduction current. Based on this result, PAn-PAA was used to modify a gold electrode (PAn-PAA\/Au) as a working electrode for the non-enzymatic detection of H2O2. The characteristics of the proposed sensors could be tuned by the PAA\/PAn molar ratio. Blending PAA with PAn enhanced the surface area, electrocatalytic activity, and conductivity of these sensors. Under optimal conditions, the linear concentration range of the H2O2 sensor was 0.04 to 12 mM with a sensitivity of 417.5 \u03bcA\/mM-cm2. This enzyme-free H2O2 sensor also exhibited a rapid response time, excellent stability, and high selectivity.<\/jats:p>","DOI":"10.3390\/s110605873","type":"journal-article","created":{"date-parts":[[2011,5,31]],"date-time":"2011-05-31T10:04:20Z","timestamp":1306836260000},"page":"5873-5885","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Preparation of a Porous Composite Film for the Fabrication of a Hydrogen Peroxide Sensor"],"prefix":"10.3390","volume":"11","author":[{"given":"Mu-Yi","family":"Hua","sequence":"first","affiliation":[{"name":"Green Technology Research Center, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan 33302, Taiwan"},{"name":"Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Tao-Yuan 33302, Taiwan"}]},{"given":"Chun-Jen","family":"Chen","sequence":"additional","affiliation":[{"name":"Green Technology Research Center, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan 33302, Taiwan"},{"name":"Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Tao-Yuan 33302, Taiwan"}]},{"given":"Hsiao-Chien","family":"Chen","sequence":"additional","affiliation":[{"name":"Green Technology Research Center, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan 33302, Taiwan"},{"name":"Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Tao-Yuan 33302, Taiwan"}]},{"given":"Rung-Ywan","family":"Tsai","sequence":"additional","affiliation":[{"name":"Electronics and Optoelectronics Research Laboratories, Industrial Technology Research Institute, Hsinchu 31040, Taiwan"}]},{"given":"Wen","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, Chung Yuan University, Tao-Yuan 33023, Taiwan"}]},{"given":"Chun-Lin","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, Chung Yuan University, Tao-Yuan 33023, Taiwan"}]},{"given":"Yin-Chih","family":"Liu","sequence":"additional","affiliation":[{"name":"Green Technology Research Center, Department of Chemical and Materials Engineering, Chang Gung University, Tao-Yuan 33302, Taiwan"},{"name":"Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Tao-Yuan 33302, Taiwan"}]}],"member":"1968","published-online":{"date-parts":[[2011,5,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.bios.2004.08.049","article-title":"Determination of hydrogen peroxide using amperometric sensor of polyaniline doped with ferrocenesulfonic acid","volume":"21","author":"Yang","year":"2005","journal-title":"Biosens. 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