{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:11:40Z","timestamp":1775643100941,"version":"3.50.1"},"reference-count":61,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2011,11,21]],"date-time":"2011-11-21T00:00:00Z","timestamp":1321833600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The optical properties of various nanostructures have been widely adopted for biological detection, from DNA sequencing to nano-scale single molecule biological function measurements. In particular, by employing localized surface plasmon resonance (LSPR), we can expect distinguished sensing performance with high sensitivity and resolution. This indicates that nano-scale detections can be realized by using the shift of resonance wavelength of LSPR in response to the refractive index change. In this paper, we overview various plasmonic nanostructures as potential sensing components. The qualitative descriptions of plasmonic nanostructures are supported by the physical phenomena such as plasmonic hybridization and Fano resonance. We present guidelines for designing specific nanostructures with regard to wavelength range and target sensing materials.<\/jats:p>","DOI":"10.3390\/s111110907","type":"journal-article","created":{"date-parts":[[2011,11,21]],"date-time":"2011-11-21T11:07:05Z","timestamp":1321873625000},"page":"10907-10929","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":289,"title":["Plasmonic Nanostructures for Nano-Scale Bio-Sensing"],"prefix":"10.3390","volume":"11","author":[{"given":"Taerin","family":"Chung","sequence":"first","affiliation":[{"name":"National Creative Research Center for Active Plasmonics Application Systems, Inter-University Semiconductor Research Center and School of Electrical Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul 151-744, Korea"}]},{"given":"Seung-Yeol","family":"Lee","sequence":"additional","affiliation":[{"name":"National Creative Research Center for Active Plasmonics Application Systems, Inter-University Semiconductor Research Center and School of Electrical Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul 151-744, Korea"}]},{"given":"Eui Young","family":"Song","sequence":"additional","affiliation":[{"name":"National Creative Research Center for Active Plasmonics Application Systems, Inter-University Semiconductor Research Center and School of Electrical Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul 151-744, Korea"}]},{"given":"Honggu","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Korea University, Seoul 136-701, Korea"}]},{"given":"Byoungho","family":"Lee","sequence":"additional","affiliation":[{"name":"National Creative Research Center for Active Plasmonics Application Systems, Inter-University Semiconductor Research Center and School of Electrical Engineering, Seoul National University, Gwanak-Gu Gwanakro 1, Seoul 151-744, Korea"}]}],"member":"1968","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"5101","DOI":"10.1021\/nn100943d","article-title":"Sensing of transcription factor through controlled-assembly of metal nanoparticles modified with segmented DNA elements","volume":"4","author":"Tan","year":"2010","journal-title":"ACS Nano"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1021\/nl0701612","article-title":"Sensing characteristics of NIR localized surface plasmon resonances in gold nanorings for application as ultrasensitive biosensors","volume":"5","author":"Larsson","year":"2007","journal-title":"Nano Lett"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"6639","DOI":"10.1021\/nn101994t","article-title":"Probing the plasmonic near-field of gold nanocrescent antennas","volume":"4","author":"Bukasov","year":"2010","journal-title":"ACS Nano"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1021\/nl900513k","article-title":"A nanocube plasmonic sensor for molecular binding on membrane surfaces","volume":"9","author":"Galush","year":"2009","journal-title":"Nano Lett"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"4188","DOI":"10.1166\/jnn.2011.3680","article-title":"Label-free detection of leptin antibody-antigen interaction by using LSPR -based optical biosensor","volume":"11","author":"Kim","year":"2011","journal-title":"J. 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