{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T08:20:55Z","timestamp":1769242855959,"version":"3.49.0"},"reference-count":23,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2012,5,8]],"date-time":"2012-05-08T00:00:00Z","timestamp":1336435200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A fluorescent probe for glutathione (GSH) detection was developed. Our study indicates a possible mechanism which couples a conjugate addition and micelle-catalyzed large membered ring formation\/elimination sequence. This method enables excellent selectivity towards GSH over other biological thiols such as cysteine (Cys) and homocysteine (Hcy). The proposed method is precise with a relative standard deviation (R.S.D) lower than 6% (n = 3) and has been successfully applied to determine GSH in human plasma with recoveries between 99.2% and 102.3%.<\/jats:p>","DOI":"10.3390\/s120505940","type":"journal-article","created":{"date-parts":[[2012,5,8]],"date-time":"2012-05-08T11:13:15Z","timestamp":1336475595000},"page":"5940-5950","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":83,"title":["A Fast Response Highly Selective Probe for the Detection of Glutathione in Human Blood Plasma"],"prefix":"10.3390","volume":"12","author":[{"given":"Yixing","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Institute of Analytical Sciences, College of Chemistry & Materials Science, Northwest University, Xi\u2019an 710069, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lovemore","family":"Hakuna","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aabha","family":"Barve","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge O.","family":"Escobedo","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Lowry","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert M.","family":"Strongin","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Portland State University, Portland, OR 97201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2012,5,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1021\/ja0668973","article-title":"A fluorescent sensor for imaging reversible redox cycles in living cells","volume":"129","author":"Miller","year":"2007","journal-title":"J. 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