{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:34:38Z","timestamp":1760243678591,"version":"build-2065373602"},"reference-count":67,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2012,6,27]],"date-time":"2012-06-27T00:00:00Z","timestamp":1340755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Nasopharyngeal carcinoma (NPC) is a common head and neck cancer. The incidence rate is higher in southern China and Southeast Asia in comparison with the Western countries. Radiotherapy is the standard treatment of NPC as the cancer cells are sensitive to ionizing radiation. Radiation treatment has good local control to patients with early NPC. It is essential to monitor the response of the NPC cells to radiation treatment in advance in order to select suitable treatment choice for the patients. This review aims to discuss the potential use of biomarkers in monitoring the responsiveness of NPC cells to radiation treatment.<\/jats:p>","DOI":"10.3390\/s120708832","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T11:17:49Z","timestamp":1340882269000},"page":"8832-8846","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Biomarkers for Use in Monitoring Responses of Nasopharyngeal Carcinoma Cells to Ionizing Radiation"],"prefix":"10.3390","volume":"12","author":[{"given":"Wei","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John Zenghong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wai Kuen","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jimmy Yuwai","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thian Sze","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2012,6,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(05)66698-6","article-title":"Nasopharyngeal carcinoma","volume":"365","author":"Wei","year":"2005","journal-title":"Lancet"},{"key":"ref_2","first-page":"1189","article-title":"The effect of migration on the risk of nasopharyngeal cancer among Chinese","volume":"34","author":"Buell","year":"1974","journal-title":"Cancer Res."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1288\/00005537-198103000-00001","article-title":"Nasopharyngeal carcinoma: An evaluation of 209 patients","volume":"91","author":"Dickson","year":"1981","journal-title":"Laryngoscope"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/bjc.1997.460","article-title":"Genomic alterations in nasopharyngeal carcinoma: Loss of heterozygosity and Epstein-Barr virus infection","volume":"76","author":"Mutirangura","year":"1997","journal-title":"Br. 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