{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:44:03Z","timestamp":1771551843420,"version":"3.50.1"},"reference-count":33,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T00:00:00Z","timestamp":1360022400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A one-dimensional photonic crystal (1DPC) based on a planar stack of dielectric layers is used as an optical transducer for biosensing, upon the coupling of TE-polarized Bloch Surface Waves (BSW). The structure is tailored with a polymeric layer providing a chemical functionality facilitating the covalent binding of orienting proteins needed for a subsequent grafting of antibodies in an immunoassay detection scheme. The polymeric layer is impregnated with Cy3 dye, in such a way that the photonic structure can exhibit an emissive behavior. The BSW-coupled fluorescence shift is used as a means for detecting refractive index variations occurring at the 1DPC surface, according to a label-free concept. The proposed working principle is successfully demonstrated in real-time tracking of protein G covalent binding on the 1DPC surface within a fluidic cell.<\/jats:p>","DOI":"10.3390\/s130202011","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T11:11:11Z","timestamp":1360062671000},"page":"2011-2022","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["A Fluorescent One-Dimensional Photonic Crystal for  Label-Free Biosensing Based on Bloch Surface Waves"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6543-6038","authenticated-orcid":false,"given":"Francesca","family":"Frascella","sequence":"first","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"given":"Serena","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0672-5793","authenticated-orcid":false,"given":"Paola","family":"Rivolo","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"given":"Valeria","family":"Moi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"given":"Fabrizio","family":"Giorgis","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"given":"Emiliano","family":"Descrovi","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienza Applicata e Tecnologia, Politecnico di Torino, corso Duca degli Abruzzi 24, Torino 10129, Italy"}]},{"given":"Francesco","family":"Michelotti","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze di Base e Applicate per l'Ingegneria, SAPIENZA Universit\u00e0 di Roma, via A. Scarpa 16, Roma 00161, Italy"}]},{"given":"Peter","family":"Munzert","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Applied Optics and Precision Engineering, Albert-Einstein-Str. 7, Jena 07745, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8927-9284","authenticated-orcid":false,"given":"Norbert","family":"Danz","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Applied Optics and Precision Engineering, Albert-Einstein-Str. 7, Jena 07745, Germany"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2648-1466","authenticated-orcid":false,"given":"Lucia","family":"Napione","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Oncologiche, Istituto per la Ricerca e la Cura del Cancro, Universit\u00e0 di Torino, Candiolo 10060, Italy"}]},{"given":"Maria","family":"Alvaro","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Oncologiche, Istituto per la Ricerca e la Cura del Cancro, Universit\u00e0 di Torino, Candiolo 10060, Italy"}]},{"given":"Federico","family":"Bussolino","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Oncologiche, Istituto per la Ricerca e la Cura del Cancro, Universit\u00e0 di Torino, Candiolo 10060, Italy"}]}],"member":"1968","published-online":{"date-parts":[[2013,2,5]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0925-4005(98)00321-9","article-title":"Surface plasmon resonance sensors: Review","volume":"54","author":"Homola","year":"1999","journal-title":"Sens. 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