{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T14:50:27Z","timestamp":1766587827880,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T00:00:00Z","timestamp":1365984000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Several kinds of modified carbon screen printed electrodes (CSPEs) for amperometric detection of hydrogen peroxide (H2O2) are presented in order to propose a methyl mercaptan (MM) biosensor. Unmodified, carbon nanotubes (CNTs), cobalt phthalocyanine (CoPC), Prussian blue (PB), and Os-wired HRP modified CSPE sensors were fabricated and tested to detect H2O2, applying a potential of +0.6 V, +0.6 V, +0.4 V, \u22120.2 V and \u22120.1 V (versus Ag\/AgCl), respectively. The limits of detection of these electrodes for H2O2 were 3.1 \u03bcM, 1.3 \u03bcM, 71 nM, 1.3 \u03bcM, 13.7 nM, respectively. The results demonstrated that the Os-wired HRP modified CSPEs gives the lowest limit of detection (LOD) for H2O2 at a working potential as low as \u22120.1 V. Os-wired HRP is the optimum choice for establishment of a MM biosensor and gives a detection limit of 0.5 \u03bcM.<\/jats:p>","DOI":"10.3390\/s130405028","type":"journal-article","created":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T03:19:09Z","timestamp":1366082349000},"page":"5028-5039","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Optimization of Hydrogen Peroxide Detection for a  Methyl Mercaptan Biosensor"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3552-7545","authenticated-orcid":false,"given":"Zhan-Hong","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Physical Chemistry of Solid Surfaces, and Department of Chemistry,  College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China"},{"name":"Laboratoire IMAGES EA 4218, Groupe Biocapteurs, Universit\u00e9 de Perpignan Via Domitia (UPVD), B\u00e2timent S, 52 av Paul Alduy 66860 Perpignan Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houssemeddine","family":"Guedri","sequence":"additional","affiliation":[{"name":"Laboratoire IMAGES EA 4218, Groupe Biocapteurs, Universit\u00e9 de Perpignan Via Domitia (UPVD), B\u00e2timent S, 52 av Paul Alduy 66860 Perpignan Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Viguier","sequence":"additional","affiliation":[{"name":"Laboratoire IMAGES EA 4218, Groupe Biocapteurs, Universit\u00e9 de Perpignan Via Domitia (UPVD), B\u00e2timent S, 52 av Paul Alduy 66860 Perpignan Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi-Gang","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Physical Chemistry of Solid Surfaces, and Department of Chemistry,  College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Louis","family":"Marty","sequence":"additional","affiliation":[{"name":"Laboratoire IMAGES EA 4218, Groupe Biocapteurs, Universit\u00e9 de Perpignan Via Domitia (UPVD), B\u00e2timent S, 52 av Paul Alduy 66860 Perpignan Cedex, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2013,4,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0003-9969(71)90063-X","article-title":"Production of volatile sulphur compounds from cysteine, cystine and methionine by human dental plague","volume":"16","author":"Tonzetich","year":"1971","journal-title":"Arch. 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