{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T10:58:58Z","timestamp":1771066738601,"version":"3.50.1"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2013,12,27]],"date-time":"2013-12-27T00:00:00Z","timestamp":1388102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A surface plasmon resonance sensor for Mycobacterium tuberculosis (MTB) deoxyribonucleic acid (DNA) is developed using repeatable telecommunication wavelength modulation based on optical fiber communications laser wavelength and stability. MTB DNA concentrations of 1 \u03bcg\/mL and 10 \u03bcg\/mL were successfully demonstrated to have the same spectral half-width in the dip for optimum coupling. The sensitivity was shown to be \u22120.087 dB\/(\u03bcg\/mL) at all applied telecommunication wavelengths and the highest sensitivity achieved was 115 ng\/mL without thiolated DNA immobilization onto a gold plate, which is better than the sensor limit of 400 ng\/mL possible with commercial biosensor equipment.<\/jats:p>","DOI":"10.3390\/s140100458","type":"journal-article","created":{"date-parts":[[2013,12,27]],"date-time":"2013-12-27T12:54:46Z","timestamp":1388148886000},"page":"458-467","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Mycobacterium tuberculosis DNA Detection Using  Surface Plasmon Resonance Modulated by  Telecommunication Wavelength"],"prefix":"10.3390","volume":"14","author":[{"given":"Shih-Hsiang","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Electronic Engineering, National Taiwan University of Science and Technology,  No. 43, Sec. 4, Keelung Rd., Taipei 10607, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Electronic Engineering, National Taiwan University of Science and Technology,  No. 43, Sec. 4, Keelung Rd., Taipei 10607, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Hsi","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Electronic Engineering, National Taiwan University of Science and Technology,  No. 43, Sec. 4, Keelung Rd., Taipei 10607, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I-Fang","family":"Tsai","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Mackay Memorial Hospital, Taipei 25160, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Ta","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Chest Medicine, Department of Internal Medicine, Mackay Memorial Hospital,  Taipei 10449, Taiwan"},{"name":"Department of Medicine, Mackay Medical College, 25245, New Taipei City, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsin-Tsung","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Medicine, Mackay Medical College, 25245, New Taipei City, Taiwan"},{"name":"Department of Laboratory Medicine, Mackay Memorial Hospital, Taipei 25160, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2013,12,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1556-276X-7-180","article-title":"Rapid identification of Mycobacterium tuberculosis infection by a new array format-based surface plasmon resonance method","volume":"7","author":"Hsieh","year":"2012","journal-title":"Nanoscale Res. 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