{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T16:47:28Z","timestamp":1776444448876,"version":"3.51.2"},"reference-count":28,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T00:00:00Z","timestamp":1394150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A simple, small size, and low cost sensor based on a Deferoxamine Self Assembled Monolayer (DFO-SAM) and Surface Plasmon Resonance (SPR) transduction, in connection with a Plastic Optical Fiber (POF), has been developed for the selective detection of Fe(III). DFO-SAM sensors based on appropriate electrochemical techniques can be frequently found in the scientific literature. In this work, we present the first example of a DFO-SAM sensor based on SPR in an optical fiber. The SPR sensing platform was realized by removing the cladding of a plastic optical fiber along half the circumference, spin coating a buffer of Microposit S1813 photoresist on the exposed core, and finally sputtering a thin gold film. The hydroxamate siderophore deferoxamine (DFO), having high binding affinity for Fe(III), is then used in its immobilized form, as self-assembled monolayer on the gold layer surface of the POF sensor. The results showed that the  DFO-SAM-POF-sensor was able to sense the formation of the Fe(III)\/DFO complex in the range of concentrations between 1 \u03bcm and 50 \u03bcm with a linearity range from 0 to 30 \u03bcm of Fe(III). The selectivity of the sensor was also proved by interference tests.<\/jats:p>","DOI":"10.3390\/s140304657","type":"journal-article","created":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T11:44:38Z","timestamp":1394192678000},"page":"4657-4671","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["A Simple Small Size and Low Cost Sensor Based on Surface Plasmon Resonance for Selective Detection of Fe(III)"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7769-0984","authenticated-orcid":false,"given":"Nunzio","family":"Cennamo","sequence":"first","affiliation":[{"name":"Department of Industrial and Information Engineering, Second University of Naples, Via Roma 29, Aversa 81031, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarla","family":"Alberti","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Pesavento","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girolamo","family":"D'Agostino","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Quattrini","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaela","family":"Biesuz","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Pavia, Via Taramelli 12, Pavia 27100, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Zeni","sequence":"additional","affiliation":[{"name":"Department of Industrial and Information Engineering, Second University of Naples, Via Roma 29, Aversa 81031, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1042\/bj3520241","article-title":"Iron regulatory proteins in pathobiology","volume":"352","author":"Cairo","year":"2000","journal-title":"Biochem. 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