{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:18:54Z","timestamp":1763140734128,"version":"build-2065373602"},"reference-count":31,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T00:00:00Z","timestamp":1422230400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Microfluidic two-phase flow detection has attracted plenty of interest in various areas of biology, medicine and chemistry. This work presents a capacitive sensor using insulated interdigital electrodes (IDEs) to detect the presence of droplets in a microchannel. This droplet sensor is composed of a glass substrate, patterned gold electrodes and an insulation layer. A polydimethylsiloxane (PDMS) cover bonded to the multilayered structure forms a microchannel. Capacitance variation induced by the droplet passage was thoroughly investigated with both simulation and experimental work. Olive oil and deionized water were employed as the working fluids in the experiments to demonstrate the droplet sensor. The results show a good sensitivity of the droplet with the appropriate measurement connection. This capacitive droplet sensor is promising to be integrated into a lab-on-chip device for in situ monitoring\/counting of droplets or bubbles.<\/jats:p>","DOI":"10.3390\/s150202694","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T13:26:37Z","timestamp":1422278797000},"page":"2694-2708","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Capacitance Variation Induced by Microfluidic Two-Phase Flow across Insulated Interdigital Electrodes in  Lab-On-Chip Devices"],"prefix":"10.3390","volume":"15","author":[{"given":"Tao","family":"Dong","sequence":"first","affiliation":[{"name":"Institute of Applied Micro-Nano Science and Technology, Chongqing Technology and Business University, Chongqing 400067, China"},{"name":"Chongqing Engineering Laboratory for Detection, Control and Integrated System, Chongqing Technology and Business University, Chongqing 400067, China"},{"name":"Department of Micro and Nano Systems Technology (IMST), Faculty of Technology and Maritime Sciences (TekMar), Buskerud and Vestfold University College (HBV), Borre 3184, Norway"}]},{"given":"C\u00e1tia","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Department of Micro and Nano Systems Technology (IMST), Faculty of Technology and Maritime Sciences (TekMar), Buskerud and Vestfold University College (HBV), Borre 3184, Norway"}]}],"member":"1968","published-online":{"date-parts":[[2015,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.drudis.2007.10.003","article-title":"Microfluidics for drug discovery and development: From target selection to product lifecycle management","volume":"13","author":"Kang","year":"2008","journal-title":"Drug Discov. 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