{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T12:21:31Z","timestamp":1768738891405,"version":"3.49.0"},"reference-count":59,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T00:00:00Z","timestamp":1422921600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Driven by the development of biomedical sensors and the availability of high mobile bandwidth, mobile health (mHealth) systems are now offering a wider range of new services. This revolution makes the idea of in-home health monitoring practical and provides the opportunity for assessment in \u201creal-world\u201d environments producing more ecologically valid data. In the field of insomnia diagnosis, for example, it is now possible to offer patients wearable sleep monitoring systems which can be used in the comfort of their homes over long periods of time. The recorded data collected from body sensors can be sent to a remote clinical back-end system for analysis and assessment. Most of the research on sleep reported in the literature mainly looks into how to automate the analysis of the sleep data and does not address the problem of the efficient encoding and secure transmissions of the collected health data. This article reviews the key enabling communication technologies and research challenges for the design of efficient mHealth systems. An end-to-end mHealth system architecture enabling the remote assessment and monitoring of patient\u2019s sleep disorders is then proposed and described as a case study. Finally, various mHealth data serialization formats and machine-to-machine (M2M) communication protocols are evaluated and compared under realistic operating conditions.<\/jats:p>","DOI":"10.3390\/s150203379","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T09:20:19Z","timestamp":1422955219000},"page":"3379-3408","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["A New mHealth Communication Framework for Use in Wearable WBANs and Mobile Technologies"],"prefix":"10.3390","volume":"15","author":[{"given":"Sana","family":"Hamida","sequence":"first","affiliation":[{"name":"Electrical and Computer Engineering Department, Texas A&M University, Doha, PO Box 23874, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elyes","family":"Hamida","sequence":"additional","affiliation":[{"name":"Qatar Mobility Innovations Center (QMIC), Qatar Science and Technology Park, Doha,  PO Box 210531, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beena","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Electrical and Computer Engineering Department, Texas A&M University, Doha, PO Box 23874, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2015,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2688","DOI":"10.1016\/j.comnet.2010.05.003","article-title":"Wireless sensor networks for healthcare: A survey","volume":"54","author":"Ersoy","year":"2010","journal-title":"Comput. Netw."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s11036-010-0260-8","article-title":"Body Area Networks: A Survey","volume":"16","author":"Chen","year":"2011","journal-title":"Mob. Netw. Appl."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1109\/JSAC.2009.090511","article-title":"Angelah: A framework for assisting elders at home","volume":"27","author":"Taleb","year":"2009","journal-title":"IEEE J. Sel. Areas Commun."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1109\/MWC.2010.5416350","article-title":"Data security and privacy in wireless body area networks","volume":"17","author":"Li","year":"2010","journal-title":"IEEE Wirel. Commun."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1109\/TITB.2012.2224876","article-title":"A New Framework Architecture for Next Generation e-Health Services","volume":"17","author":"Fengou","year":"2013","journal-title":"IEEE J. Biomed. Health Inform."},{"key":"ref_6","unstructured":"Chakravorty, R. (2006, January 13\u201317). A programmable service architecture for mobile medical care. Pisa, Italy."},{"key":"ref_7","unstructured":"Jea, D., and Srivastava, M.B. (2006, January 19\u201322). A remote medical monitoring and interaction system. Uppsala, Sweden."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"D\u0103gta\u015f, S., Pekhteryev, G., \u015eahin\u014fglu, Z., \u00c7am, H., and Challa, N. (2008). Real-Time and Secure Wireless Health Monitoring. Int. J. Telemed. Appl.","DOI":"10.1155\/2008\/135808"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s11277-010-0078-5","article-title":"Remote Patient Monitoring Within a Future 5G Infrastructure","volume":"57","author":"Oleshchuk","year":"2011","journal-title":"Wirel. Pers. Commun."},{"key":"ref_10","unstructured":"Shelby, Z., Hartke, K., and Bormann, C. draft-ietf-core-coap-18; IETF: city, country; CoRE Working Group, 2013. Available online: https:\/\/tools.ietf.org\/html\/draft-ietf-core-coap-18."},{"key":"ref_11","unstructured":"Banks, A., and Gupta, R. MQTT Version 3.1.1 Protocol Specification; OASIS, Committee Specification Draft 02, April 2014. Available online: http:\/\/docs.oasis-open.org\/mqtt\/mqtt\/v3.1.1\/csprd02\/mqtt-v3.1.1-csprd02.html."},{"key":"ref_12","unstructured":"Stanford-Clark, A., and Truong, H.L. MQTT For Sensor Networks (MQTT-SN) Protocol Specification; IBM: 2013. Available online: http:\/\/mqtt.org\/new\/wp-content\/uploads\/2009\/06\/MQTT-SN_spec_v1.2.pdf."},{"key":"ref_13","unstructured":"Godfrey, R., Ingham, D., and Schloming, R. OASIS Advanced Message Queuing Protocol (AMQP) Version 1.0; OASIS Standard. Available online: http:\/\/docs.oasis-open.org\/amqp\/core\/v1.0\/os\/amqp-core-complete-v1.0-os.pdf."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Thangavel, D., Ma, X., Valera, A., Tan, H.-X., and Tan, C.-Y. (2014, January 21\u201324). Performance evaluation of MQTT and CoAP via a common middleware. Singapore.","DOI":"10.1109\/ISSNIP.2014.6827678"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"De Caro, N., Colitti, W., Steenhaut, K., Mangino, G., and Reali, G. (2013, January 21). Comparison of two lightweight protocols for smartphone-based sensing. Namur, Belgium.","DOI":"10.1109\/SCVT.2013.6735994"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Bandyopadhyay, S., and Bhattacharyya, A. (2013, January 28\u201331). Lightweight Internet protocols for web enablement of sensors using constrained gateway devices. San Diego, CA, USA.","DOI":"10.1109\/ICCNC.2013.6504105"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Collina, M., Bartolucci, M., Vanelli-Coralli, A., and Corazza, G.E. (2014, January 8\u201310). Internet of Things application layer protocol analysis over error and delay prone links. Livorno, Italy.","DOI":"10.1109\/ASMS-SPSC.2014.6934573"},{"key":"ref_18","unstructured":"Shafranovich, Y. Common Format and MIME Type for Comma-Separated Values (CSV) Files. Available online: http:\/\/tools.ietf.org\/html\/rfc4180.html."},{"key":"ref_19","unstructured":"Crockford, D. The Application\/JSON Media Type for JavaScript Object Notation (JSON). Available online: http:\/\/tools.ietf.org\/html\/rfc4627."},{"key":"ref_20","unstructured":"Bray, T., Paoli, J., Sperberg-McQueen, C.M., Maler, E., and Yergeau, F. Extensible Markup Language (XML) 1.0 (Fifth Edition). Available online: http:\/\/www.w3.org\/TR\/REC-xml\/."},{"key":"ref_21","unstructured":"BSON\u2014Binary JSON Version 1.0. Available online: http:\/\/bsonspec.org."},{"key":"ref_22","unstructured":"Message Pack\u2014Format Specification. Available online: http:\/\/msgpack.org."},{"key":"ref_23","unstructured":"Protocol Buffers\u2014Google's Data Interchange Format. Available online: http:\/\/code.google.com\/p\/protobuf."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s12264-007-0035-9","article-title":"Objective and subjective measures for sleep disorders","volume":"23","author":"Zhang","year":"2007","journal-title":"Neurosci. Bull."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"9153","DOI":"10.3390\/s140509153","article-title":"Surveying Wearable Human Assistive Technology for Life and Safety Critical Applications: Standards, Challenges and Opportunities","volume":"14","author":"Alam","year":"2014","journal-title":"Sensors"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Fielding, R., Gettys, J., Mogul, J., Frystyk, H., Masinter, L., Leach, P., and Berners-Lee, T. Hypertext Transfer Protocol\u2014HTTP\/1.1; IETF Standard, RFC 2616, 1999. Available online: http:\/\/www.rfc-base.org\/rfc-2616.html.","DOI":"10.17487\/rfc2616"},{"key":"ref_27","unstructured":"Xively. Available online: https:\/\/xively.com\/."},{"key":"ref_28","unstructured":"Mango M2M Platform. Available online: http:\/\/forum.infiniteautomation.com\/."},{"key":"ref_29","unstructured":"StormMQ. Available online: http:\/\/stormmq.com\/."},{"key":"ref_30","first-page":"480","article-title":"Ambulatory monitoring of sleep disorders","volume":"60","author":"Tahmasian","year":"2010","journal-title":"J. Pak. Med. Assoc."},{"key":"ref_31","first-page":"737","article-title":"Portable Monitoring Task Force of the American Academy of Sleep Medicine Clinical Guidelines for the Use of Unattended Portable Monitors in the Diagnosis of Obstructive Sleep Apnea in Adult Patients","volume":"3","author":"Collop","year":"2010","journal-title":"J. Clin. Sleep Med."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1183\/09059180.00004213","article-title":"Ambulatory monitoring in the diagnosis and management of obstructive sleep apnoea syndrome","volume":"22","author":"Pepin","year":"2013","journal-title":"Eur. Respir. Rev."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/sleep\/23.2.1k","article-title":"Practice Parameters for the Evaluation of Chronic Insomnia","volume":"23","author":"Chesson","year":"2000","journal-title":"Sleep"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/sleep\/15.2.173","article-title":"EEG Arousals: Scoring Rules And Examples: A Preliminary Report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association","volume":"15","author":"Bonnet","year":"1992","journal-title":"Sleep"},{"key":"ref_35","unstructured":"Neurovigil, The iBrain Device. Available online: http:\/\/www.neurovigil.com\/ibrain\/."},{"key":"ref_36","unstructured":"Advanced Brain Monitoring. Available online: Advanced Sleep Group. Available online: http:\/\/advancedbrainmonitoring.com\/."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Grundlehner, B., Brown, L., Penders, J., and Gyselinckx, B. (2009, January 3\u20135). The Design and Analysis of a Real-Time, Continuous Arousal Monitor. Berkeley, CA, USA.","DOI":"10.1109\/BSN.2009.21"},{"key":"ref_38","unstructured":"WatchPAT. Available online: http:\/\/www.itamar-medical.com\/."},{"key":"ref_39","unstructured":"Ambulatory Monitoring, Inc. Available online: http:\/\/www.ambulatory-monitoring.com\/."},{"key":"ref_40","unstructured":"ActiGraph, ActiSleep Sleep Monitor. Available online: http:\/\/www.theactigraph.com\/products\/actisleep\/."},{"key":"ref_41","unstructured":"Bonato, P. (September, January 31). Advances in wearable technology and its medical applications. Buenos Aires, Argentina."},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Jovanov, E., Hanish, N., Courson, V., Stidham, J., Stinson, H., Webb, C., and Denny, K. (2009, January 3\u20136). Avatar\u2014A multi-sensory system for real time body position monitoring. Minneapolis, MN, USA.","DOI":"10.1109\/IEMBS.2009.5334774"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1109\/TITB.2009.2038484","article-title":"BIOTEX\u2014Biosensing textiles for personalised healthcare management","volume":"14","author":"Coyle","year":"2010","journal-title":"IEEE Trans. Inf. Technol. Biomed."},{"key":"ref_44","doi-asserted-by":"crossref","unstructured":"Matthews, R., McDonald, N., Hervieux, P., Turner, P., and Steindorf, M. (2007, January 22\u201326). A Wearable Physiological Sensor Suite for Unobtrusive Monitoring of Physiological and Cognitive State. Lyon, France.","DOI":"10.1109\/IEMBS.2007.4353532"},{"key":"ref_45","unstructured":"IMPAK Health. Available online: http:\/\/www.impakhealth.com\/."},{"key":"ref_46","unstructured":"Occhiuzzi, C., and Marrocco, G. (2009, January 23\u201327). RFID technology for the neuroscience: Feasibility of sleep disease monitoring. Berlin, German."},{"key":"ref_47","unstructured":"SAMi the Sleep Activity Monitor. Available online: http:\/\/www.samialert.com\/."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Gupta, B., Cianca, E., Ruggieri, M., and Prasad, R. (2009, January 24\u201327). A Novel FM-UWB System for Vital Sign Monitoring and its Comparison with IR-UWB. Bratislava, Slovakia.","DOI":"10.1109\/ISABEL.2009.5373708"},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Otsu, M., Nakamura, R., and Kajiwara, A. (2011, January 22\u201324). Remote Respiration Monitoring Sensor Using Stepped-FM. San Antonio, TX, USA.","DOI":"10.1109\/SAS.2011.5739784"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Higashikaturagi, K., Nakahata, Y., Matsunami, I., and Kajiwara, A. (2008, January 10\u201312). Non-Invasive Respiration Monitoring Sensor Using UWB-IR. Hannover, Germany.","DOI":"10.1109\/ICUWB.2008.4653294"},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Taylor, M., Grant, T., Knoefel, F., and Goubran, R. (2013, January 4\u20135). Bed occupancy measurements using under mattress pressure sensors for long term monitoring of community-dwelling older adults. Gatineau, QC, Canada.","DOI":"10.1109\/MeMeA.2013.6549721"},{"key":"ref_52","unstructured":"Gtec-Mobilab. Available online: http:\/\/www.gtec.at\/Products\/Hardware-and-Accessories\/g.MOBIlab-Specs-Features."},{"key":"ref_53","unstructured":"Titanium, E. Portable, Lightweight, Wireless PSG System. Available online: http:\/\/www.embla.com\/index.cfm\/id\/42\/titanium\/."},{"key":"ref_54","unstructured":"Somte (Compumedics). Available online: http:\/\/www.compumedics.com.au\/index.php\/sleep-diagnostics\/home-sleep-testing\/full-psg-home-sleep-testing\/somte-psg."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/00004691-199607000-00004","article-title":"Past and future of computer-assisted sleep analysis and drowsiness assessment","volume":"13","author":"Hasan","year":"1996","journal-title":"J. Clin. Neurophysiol."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Yousaf, F., Tmar-Ben Hamida, S., and Ahmed, B. (2014, January 17\u201320). Sleep eDiary: A Mobile Health Application for Insomnia Assessment. Doha, Qatar.","DOI":"10.1109\/MECBME.2014.6783260"},{"key":"ref_57","unstructured":"Dierks, T., and Rescorla, E. The Transport Layer Security (TLS) Protocol\u2014Version 1.2. Available online: http:\/\/www.ietf.org\/rfc\/rfc5246.txt."},{"key":"ref_58","unstructured":"Rescorla, E., and Modadugu, N. Datagram Transport Layer Security\u2014Version 1.2. Available online: http:\/\/tools.ietf.org\/html\/rfc6347."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Hamida, S.T.-B., Hamida, E.B., Ahmed, B., and Abu-Dayya, A. (2013, January 10\u201313). Towards Esfficient and Secure in-Home Wearable Insomnia Monitoring and Diagnosis System. Chania, Greece.","DOI":"10.1109\/BIBE.2013.6701671"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/15\/2\/3379\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T20:42:16Z","timestamp":1760215336000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/15\/2\/3379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,3]]},"references-count":59,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,2]]}},"alternative-id":["s150203379"],"URL":"https:\/\/doi.org\/10.3390\/s150203379","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,3]]}}}