{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T18:10:04Z","timestamp":1770919804421,"version":"3.50.1"},"reference-count":40,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T00:00:00Z","timestamp":1424044800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>We present a small, compact and portable device for point-of-care instantaneous early detection of anemia. The method used is based on direct hematocrit measurement from whole blood samples by means of impedance analysis. This device consists of a custom electronic instrumentation and a plug-and-play disposable sensor. The designed electronics rely on straightforward standards for low power consumption, resulting in a robust and low consumption device making it completely mobile with a long battery life. Another approach could be powering the system based on other solutions like indoor solar cells, or applying energy-harvesting solutions in order to remove the batteries. The sensing system is based on a disposable low-cost label-free three gold electrode commercial sensor for 50 \u00b5L blood samples. The device capability for anemia detection has been validated through 24 blood samples, obtained from four hospitalized patients at Hospital Cl\u00ednic. As a result, the response, effectiveness and robustness of the portable point-of-care device to detect anemia has been proved with an accuracy error of 2.83% and a mean coefficient of variation of 2.57% without any particular case above 5%.<\/jats:p>","DOI":"10.3390\/s150204564","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T10:30:38Z","timestamp":1424082638000},"page":"4564-4577","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["An Instantaneous Low-Cost Point-of-Care Anemia  Detection Device"],"prefix":"10.3390","volume":"15","author":[{"given":"Jaime","family":"Punter-Villagrasa","sequence":"first","affiliation":[{"name":"Department of Electronics, University of Barcelona, Mart\u00ed i Franqu\u00e8s 1, Barcelona 08028, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"Cid","sequence":"additional","affiliation":[{"name":"Department of Hemotherapy and Hemostasis, CDB, IDIBAPS, Hospital Cl\u00ednic, Villarroel 170, Barcelona 08036, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2294-4267","authenticated-orcid":false,"given":"Cristina","family":"P\u00e1ez-Avil\u00e9s","sequence":"additional","affiliation":[{"name":"Department of Electronics, University of Barcelona, Mart\u00ed i Franqu\u00e8s 1, Barcelona 08028, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00f3n","family":"Rodr\u00edguez-Villarreal","sequence":"additional","affiliation":[{"name":"Centre de Recerca Matem\u00e0tica, Campus Bellaterra, UAB, Edifici C, Barcelona 08193, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esteve","family":"Juanola-Feliu","sequence":"additional","affiliation":[{"name":"Department of Electronics, University of Barcelona, Mart\u00ed i Franqu\u00e8s 1, Barcelona 08028, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordi","family":"Colomer-Farrarons","sequence":"additional","affiliation":[{"name":"Department of Electronics, University of Barcelona, Mart\u00ed i Franqu\u00e8s 1, Barcelona 08028, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pere","family":"Miribel-Catal\u00e0","sequence":"additional","affiliation":[{"name":"Department of Electronics, University of Barcelona, Mart\u00ed i Franqu\u00e8s 1, Barcelona 08028, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2015,2,16]]},"reference":[{"key":"ref_1","unstructured":"World Health Organization (WHO) Anaemia. 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