{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:22:13Z","timestamp":1770740533620,"version":"3.49.0"},"reference-count":23,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2015,7,24]],"date-time":"2015-07-24T00:00:00Z","timestamp":1437696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003693","name":"Korea Institute of Science and Technology","doi-asserted-by":"publisher","award":["2E25590"],"award-info":[{"award-number":["2E25590"]}],"id":[{"id":"10.13039\/501100003693","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003693","name":"Korea Institute of Science and Technology","doi-asserted-by":"publisher","award":["2E25690"],"award-info":[{"award-number":["2E25690"]}],"id":[{"id":"10.13039\/501100003693","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Dual Use Technology Center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Preventing unexpected explosive attacks and tracing explosion-related molecules require the development of highly sensitive gas-vapor detection systems. For that purpose, a micromechanical cantilever-based olfactory sensing system including a sample preconcentrator was developed to detect 2,4-dinitrotoluene (2,4-DNT), which is a  well-known by-product of the explosive molecule trinitrotoluene (TNT) and exists in concentrations on the order of parts per billion in the atmosphere at room temperature. A peptide receptor (His-Pro-Asn-Phe-Ser-Lys-Tyr-Ile-Leu-His-Gln-Arg) that has high binding affinity for 2,4-DNT was immobilized on the surface of the cantilever sensors to detect  2,4-DNT vapor for highly selective detection. A micro-preconcentrator (\u00b5PC) was developed using Tenax-TA adsorbent to produce higher concentrations of 2,4-DNT molecules. The preconcentration was achieved via adsorption and thermal desorption phenomena occurring between target molecules and the adsorbent. The \u00b5PC directly integrated with a cantilever sensor and enhanced the sensitivity of the cantilever sensor as a pretreatment tool for the target vapor. The response was rapidly saturated within 5 min and sustained for more than 10 min when the concentrated vapor was introduced. By calculating preconcentration factor values, we verified that the cantilever sensor provides up to an eightfold improvement in sensing performance.<\/jats:p>","DOI":"10.3390\/s150818167","type":"journal-article","created":{"date-parts":[[2015,7,24]],"date-time":"2015-07-24T10:44:26Z","timestamp":1437734666000},"page":"18167-18177","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["A Micro-Preconcentrator Combined Olfactory Sensing System with a Micromechanical Cantilever Sensor for Detecting  2,4-Dinitrotoluene Gas Vapor"],"prefix":"10.3390","volume":"15","author":[{"given":"Myung-Sic","family":"Chae","sequence":"first","affiliation":[{"name":"Center for BioMicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Korea"},{"name":"School of Electrical Engineering, Korea University, Seoul 136-701, Korea"}]},{"given":"Jinsik","family":"Kim","sequence":"additional","affiliation":[{"name":"Center for BioMicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Korea"}]},{"given":"Yong","family":"Yoo","sequence":"additional","affiliation":[{"name":"Center for BioMicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Korea"},{"name":"Department of Electrical Engineering, Kwangwoon University, Seoul 139-701, Korea"}]},{"given":"Ji","family":"Kang","sequence":"additional","affiliation":[{"name":"Center for BioMicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7344-6060","authenticated-orcid":false,"given":"Jeong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Kwangwoon University, Seoul 139-701, Korea"}]},{"given":"Kyo","family":"Hwang","sequence":"additional","affiliation":[{"name":"Center for BioMicrosystems, Korea Institute of Science and Technology, Seoul 136-791, Korea"}]}],"member":"1968","published-online":{"date-parts":[[2015,7,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev-anchem-060908-155232","article-title":"Micro- and Nanocantilever Devices and Systems for Biomolecule Detection","volume":"2","author":"Hwang","year":"2009","journal-title":"Annu. 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