{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T05:10:34Z","timestamp":1775365834505,"version":"3.50.1"},"reference-count":66,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T00:00:00Z","timestamp":1480464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Since humidity sensors have been widely used in many sectors, a suitable humidity sensing material with improved sensitivity, faster response and recovery times, better stability and low hysteresis is necessary to be developed. Here, we fabricate a uniformly porous humidity sensor using Ca, Ti substituted Mg ferrites with chemical formula of CaMgFe1.33Ti3O12 as humidity sensing materials by solid-sate step-sintering technique. This synthesis technique is useful to control the grain size with increased porosity to enhance the hydrophilic characteristics of the CaMgFe1.33Ti3O12 nanoceramic based sintered electro-ceramic nanocomposites. The highest porosity, lowest density and excellent surface-hydrophilicity properties were obtained at 1050 \u00b0C sintered ceramic. The performance of this impedance type humidity sensor was evaluated by electrical characterizations using alternating current (AC) in the 33%\u201395% relative humidity (RH) range at 25 \u00b0C. Compared with existing conventional resistive humidity sensors, the present sintered electro-ceramic nanocomposite based humidity sensor showed faster response time (20 s) and recovery time (40 s). This newly developed sensor showed extremely high sensitivity (%S) and small hysteresis of &lt;3.4%. Long-term stability of the sensor had been determined by testing for 30 consecutive days. Therefore, the high performance sensing behavior of the present electro-ceramic nanocomposites would be suitable for a potential use in advanced humidity sensors.<\/jats:p>","DOI":"10.3390\/s16122029","type":"journal-article","created":{"date-parts":[[2016,11,30]],"date-time":"2016-11-30T10:10:36Z","timestamp":1480500636000},"page":"2029","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Uniformly Porous Nanocrystalline CaMgFe1.33Ti3O12 Ceramic Derived Electro-Ceramic Nanocomposite for Impedance Type Humidity Sensor"],"prefix":"10.3390","volume":"16","author":[{"given":"Ashis","family":"Tripathy","sequence":"first","affiliation":[{"name":"Centre for Applied Biomechanics, Department of Biomedical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia"}]},{"given":"Sumit","family":"Pramanik","sequence":"additional","affiliation":[{"name":"Centre for Applied Biomechanics, Department of Biomedical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia"}]},{"given":"Ayan","family":"Manna","sequence":"additional","affiliation":[{"name":"Centre for Applied Biomechanics, Department of Biomedical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia"}]},{"given":"Hanie","family":"Shasmin","sequence":"additional","affiliation":[{"name":"Centre for Applied Biomechanics, Department of Biomedical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia"}]},{"given":"Zamri","family":"Radzi","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry &amp; Orthodontics, Faculty of Dentistry, University of Malaya, Kuala Lumpur 50603, Malaysia"}]},{"given":"Noor","family":"Abu Osman","sequence":"additional","affiliation":[{"name":"Centre for Applied Biomechanics, Department of Biomedical Engineering, University of Malaya, Kuala Lumpur 50603, Malaysia"}]}],"member":"1968","published-online":{"date-parts":[[2016,11,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1166\/sl.2005.045","article-title":"Humidity sensors: A review of materials and mechanisms","volume":"3","author":"Chen","year":"2005","journal-title":"Sens. Lett."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S1369-7021(10)70126-7","article-title":"Metal oxide nanowires as chemical sensors","volume":"13","author":"Comini","year":"2010","journal-title":"Mater. Today"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1126\/science.287.5453.622","article-title":"Nanotube molecular wires as chemical sensors","volume":"287","author":"Kong","year":"2000","journal-title":"Science"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1109\/JSEN.2011.2156781","article-title":"Si nanowire-based humidity sensors prepared on glass substrate","volume":"11","author":"Hsueh","year":"2011","journal-title":"IEEE Sens. J."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1021\/ja028371y","article-title":"Polyaniline nanofibers: Facile synthesis and chemical sensors","volume":"125","author":"Huang","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0925-4005(94)01268-M","article-title":"Ceramic sensors for humidity detection: The state-of-the-art and future developments","volume":"23","author":"Traversa","year":"1995","journal-title":"Sens. Actuators B Chem."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0925-4005(99)00226-9","article-title":"Humidity sensors for automotive, appliances and consumer applications","volume":"59","author":"Patissier","year":"1999","journal-title":"Sens. Actuators B Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"16343","DOI":"10.3390\/s140916343","article-title":"Role of morphological structure, doping, and coating of different materials in the sensing characteristics of humidity sensors","volume":"14","author":"Tripathy","year":"2014","journal-title":"Sensors"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"8366","DOI":"10.1021\/nn402728g","article-title":"Flexible sensors based on nanoparticles","volume":"7","author":"Haick","year":"2013","journal-title":"ACS Nano"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1109\/19.492787","article-title":"Sensor for high-air-humidity measurement","volume":"45","author":"Matko","year":"1996","journal-title":"IEEE Trans. Instrum. Meas."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"4474","DOI":"10.3390\/s110504474","article-title":"Next generation at-cut quartz crystal sensing devices","volume":"11","author":"Matko","year":"2011","journal-title":"Sensors"},{"key":"ref_12","first-page":"717","article-title":"Chemical and biological sensors, part II","volume":"Volume 3","author":"Hesse","year":"1992","journal-title":"Sensors: A Comprehensive Survey"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"355502","DOI":"10.1088\/0957-4484\/21\/35\/355502","article-title":"Self-assembled copolymeric nanoparticles as chemically interactive materials for humidity sensors","volume":"21","author":"Venditti","year":"2010","journal-title":"Nanotechnology"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.snb.2015.11.001","article-title":"Role of nanostructured polymers on the improvement of electrical response-based relative humidity sensors","volume":"225","author":"Fratoddi","year":"2016","journal-title":"Sens. Actuators B Chem."},{"key":"ref_15","first-page":"498","article-title":"Humidity Sensors Using Ceramic Materials","volume":"Volume 93-7","author":"Butler","year":"1993","journal-title":"Proceedings of the Symposium on Chemical Sensors II"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0250-6874(86)80055-5","article-title":"Humidity sensors: Principles and applications","volume":"10","author":"Yamazoe","year":"1986","journal-title":"Sens. Actuators"},{"key":"ref_17","first-page":"119","article-title":"Reliability and reproducibility of ceramic sensors. III: Humidity sensors","volume":"72","author":"Fagan","year":"1993","journal-title":"Am. Ceram. Soc. Bull."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0250-6874(85)87002-5","article-title":"Theoretical studies on the impedance-humidity characteristics of ceramic humidity sensors","volume":"7","author":"Shimizu","year":"1985","journal-title":"Sens. Actuators"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0250-6874(89)87058-1","article-title":"Porosity control of humidity-sensitive ceramics and theoretical model of humidity-sensitive characteristics","volume":"19","author":"Ping","year":"1989","journal-title":"Sens. Actuators"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"8863","DOI":"10.1016\/S1452-3981(23)12933-6","article-title":"Developments of immobilized surface modified piezoelectric crystal biosensors for advanced applications","volume":"8","author":"Pramanik","year":"2013","journal-title":"Int. J. Electrochem. Sci."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1007\/s00604-015-1678-2","article-title":"A resistive type humidity sensor based on crystalline tin oxide nanoparticles encapsulated in polyaniline matrix","volume":"183","author":"Shukla","year":"2016","journal-title":"Microchim. Acta"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.snb.2005.10.028","article-title":"Structure and humidity sensitive electrical properties of the Sn4+ and\/or Mo6+ substituted Mg ferrite","volume":"115","author":"Rezlescu","year":"2006","journal-title":"Sens. Actuators B Chem."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.materresbull.2005.07.019","article-title":"MgFe2O4 pigment obtained at low temperature","volume":"41","author":"Candeia","year":"2006","journal-title":"Mater. Res. Bull."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0039-6028(02)02464-0","article-title":"Reactivity of a reduced metal oxide surface: Hydrogen, water and carbon monoxide adsorption on oxygen defective rutile TiO2 (110)","volume":"524","author":"Menetrey","year":"2003","journal-title":"Surf. Sci."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0925-4005(03)00346-0","article-title":"EPR studies of some thick film ferrates, aluminates and their correlation with humidity sensitivity","volume":"94","author":"Misra","year":"2003","journal-title":"Sens. Actuators B Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0925-4005(00)00368-3","article-title":"Reducing gas-sensing properties of ferrite compounds MFe2O4 (M=Cu, Zn, Cd and Mg)","volume":"66","author":"Chen","year":"2000","journal-title":"Sens. Actuators B Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"145503","DOI":"10.1088\/0957-4484\/18\/14\/145503","article-title":"Fast humidity sensors based on CeO2 nanowires","volume":"18","author":"Fu","year":"2007","journal-title":"Nanotechnology"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jallcom.2011.10.038","article-title":"Ac impedance studies on LiFe5\u2212xMnxO8 ferrites","volume":"513","author":"Ramesh","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jallcom.2011.08.096","article-title":"Structural, magnetic and electrical properties of Al3+ substituted Ni\u2013Zn ferrite nanoparticles","volume":"511","author":"Hashim","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jallcom.2011.08.087","article-title":"Influence of MnO2 on the sintering behavior and magnetic properties of NiFe2O4 ferrite ceramics","volume":"510","author":"Du","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jallcom.2011.12.159","article-title":"Magnetic and dielectric behavior of terbium substituted Mg1\u2212xTbxFe2O4 ferrites","volume":"519","author":"Khan","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jallcom.2011.10.001","article-title":"Influence of Nd3+ substitution on structural, electrical and magnetic properties of nanocrystalline nickel ferrites","volume":"513","author":"Shinde","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.jallcom.2011.11.022","article-title":"Grain growth kinetics and magnetic properties of Ni\u2013Zn ferrite thin films","volume":"513","author":"Li","year":"2012","journal-title":"J. Alloys Compd."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1016\/j.matlet.2005.03.072","article-title":"Structural and magnetic properties of ZnxCu1.4\u2212xMn0.4Fe1.2O4 ferrites","volume":"59","author":"Birajdar","year":"2005","journal-title":"Mater. Lett."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0022-5088(91)90298-I","article-title":"Dc conductivity and dielectric behavior of Ti4+ substituted Mg\u2013Zn ferrites","volume":"168","author":"Suryavanshi","year":"1991","journal-title":"J. Less Common Met."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/pssa.2211200231","article-title":"Electrical conductivity of some mixed Li\u2013Ti ferrites","volume":"120","author":"Reddy","year":"1990","journal-title":"Phys. Status Solidi A"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S0304-8853(02)01212-X","article-title":"Effect of tetravalent titanium ions substitution on the dielectric properties of Co\u2013Zn ferrites","volume":"257","author":"Meaz","year":"2003","journal-title":"J. Magn. Magn. Mater."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0022-5088(85)90240-1","article-title":"Dielectric behaviour of tetravalent titanium-substituted Ni\u2013Zn ferrites","volume":"107","author":"Prakash","year":"1985","journal-title":"J. Less Common Met."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/0025-5408(89)90194-3","article-title":"Xrd and magnetic studies on Ti-substituted Mg\u2013Zn ferrites","volume":"24","author":"Suryavanshi","year":"1989","journal-title":"Mater. Res. Bull."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jallcom.2008.01.139","article-title":"Influence of the doping of Ti4+ ions on electrical and magnetic properties of Mn1+xFe2\u22122xTixO4 ferrite","volume":"469","author":"Farea","year":"2009","journal-title":"J. Alloys Compd."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.3390\/s16071135","article-title":"Design and development for capacitive humidity sensor applications of lead-free Ca, Mg, Fe, Ti-oxides-based electro-ceramics with improved sensing properties via physisorption","volume":"16","author":"Tripathy","year":"2016","journal-title":"Sensors"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3390\/ma6010065","article-title":"Morphological change of heat treated bovine bone: A comparative study","volume":"6","author":"Pramanik","year":"2013","journal-title":"Materials"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"292","DOI":"10.3390\/s16030292","article-title":"Synthesis and characterizations of novel Ca-Mg-Ti-Fe-oxides based ceramic nanocrystals and flexible film of polydimethylsiloxane composite with improved mechanical and dielectric properties for sensors","volume":"16","author":"Tripathy","year":"2016","journal-title":"Sensors"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"9806","DOI":"10.1038\/srep09806","article-title":"In vitro study of surface modified poly (ethylene glycol)-impregnated sintered bovine bone scaffolds on human fibroblast cells","volume":"5","author":"Pramanik","year":"2015","journal-title":"Sci. Rep."},{"key":"ref_45","first-page":"881","article-title":"The influence of the heat treatment on the humidity sensitivity of magnesium nanoferrite","volume":"12","author":"Doroftei","year":"2010","journal-title":"J. Optoelectron. Adv. Mater."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"5843","DOI":"10.1038\/srep05843","article-title":"Design and development of potential tissue engineering scaffolds from structurally different longitudinal parts of a bovine-femur","volume":"4","author":"Pramanik","year":"2014","journal-title":"Sci. Rep."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1002\/jbm.a.35186","article-title":"Endothelial cell responses in terms of adhesion, proliferation, and morphology to stiffness of polydimethylsiloxane elastomer substrates","volume":"103","author":"Ataollahi","year":"2015","journal-title":"J. Biomed. Mater. Res. Part A"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/jccs.201000129","article-title":"Synthesis and characterization of ilmenite-type cobalt titanate powder","volume":"57","author":"Chuang","year":"2010","journal-title":"J. Chin. Chem. Soc."},{"key":"ref_49","unstructured":"Yazawa, Y., Yamaguchi, A., and Takeda, H. (2012). Moon, Springer."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.jmst.2013.12.002","article-title":"Humidity effect on transport properties of titanium dioxide nanoparticles","volume":"30","author":"Usman","year":"2014","journal-title":"J. Mater. Sci. Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.sna.2010.08.030","article-title":"Humidity-sensitive properties based on liquid state LiZnVO4-doped SnO2","volume":"163","author":"Hu","year":"2010","journal-title":"Sens. Actuators A Phys."},{"key":"ref_52","first-page":"9","article-title":"Morphological and relative humidity sensing properties of pure ZnO nanomaterial","volume":"122","author":"Pandey","year":"2010","journal-title":"Sens. Transducers"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.ceramint.2012.06.048","article-title":"Excellent humidity sensing properties of cadmium titanate nanofibers","volume":"39","author":"Imran","year":"2013","journal-title":"Ceram. Int."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.ceramint.2007.09.030","article-title":"Improvement of response characteristics of TiO2 humidity sensors by simultaneous addition of Li2O and V2O5","volume":"34","author":"Aoki","year":"2008","journal-title":"Ceram. Int."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0925-4005(03)00371-X","article-title":"Sol\u2013gel batio3 thin film for humidity sensors","volume":"94","author":"Yuk","year":"2003","journal-title":"Sens. Actuators B Chem."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"7379","DOI":"10.1016\/j.ceramint.2013.02.077","article-title":"Porous ZnAl2O4 spinel nanorods: High sensitivity humidity sensors","volume":"39","author":"Cheng","year":"2013","journal-title":"Ceram. Int."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.apsusc.2004.08.013","article-title":"Zinc oxide nanorod and nanowire for humidity sensor","volume":"242","author":"Zhang","year":"2005","journal-title":"Appl. Surf. Sci."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.snb.2007.07.012","article-title":"Study on humidity sensing properties based on composite materials of Li-doped mesoporous silica A-SBA-15","volume":"128","author":"Zhang","year":"2008","journal-title":"Sens. Actuators B Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.sna.2011.10.007","article-title":"Study of the influence of nickel ions substitutes in barium stannates used as humidity resistive sensors","volume":"173","author":"Doroftei","year":"2012","journal-title":"Sens. Actuators A Phys."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.snb.2008.03.028","article-title":"Study on humidity sensing property based on Li-doped mesoporous silica MCM-41","volume":"133","author":"Wang","year":"2008","journal-title":"Sens. Actuators B Chem."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.snb.2010.06.036","article-title":"Preparation and humidity sensitive property of mesoporous ZnO\u2013SiO2 composite","volume":"149","author":"Yuan","year":"2010","journal-title":"Sens. Actuators B Chem."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.snb.2010.02.030","article-title":"Humidity sensing properties of batio3 nanofiber prepared via electrospinning","volume":"146","author":"He","year":"2010","journal-title":"Sens. Actuators B Chem."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S0254-0584(02)00421-2","article-title":"Preparation and electrical properties of humidity sensing films of BaTiO3\/polystrene sulfonic sodium","volume":"78","author":"Wang","year":"2003","journal-title":"Mater. Chem. Phys."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/0009-2614(95)00905-J","article-title":"The grotthuss mechanism","volume":"244","author":"Agmon","year":"1995","journal-title":"Chem. Phys. Lett."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0925-4005(99)00511-0","article-title":"Study of the performance degradation of thin film aluminum oxide sensor at high humidity","volume":"63","author":"Nahar","year":"2000","journal-title":"Sens. Actuators B Chem."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/0022-3697(94)90575-4","article-title":"Impedance and dielectric spectroscopy revisited: Distinguishing localized relaxation from long-range conductivity","volume":"55","author":"Gerhardt","year":"1994","journal-title":"J. Phys. Chem. Solids"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/16\/12\/2029\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T19:27:46Z","timestamp":1760210866000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/16\/12\/2029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,30]]},"references-count":66,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2016,12]]}},"alternative-id":["s16122029"],"URL":"https:\/\/doi.org\/10.3390\/s16122029","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,30]]}}}