{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:49:22Z","timestamp":1768294162814,"version":"3.49.0"},"reference-count":42,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T00:00:00Z","timestamp":1484870400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Breath acetone serves as a biomarker for diabetes. This article reports 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF4]), a type of room temperature ionic liquid (RTIL), as a selective sensing material for acetone. The RTIL sensing layer was coated on a quartz crystal microbalance (QCM) for detection. The sensing mechanism is based on a decrease in viscosity and density of the [bmim][BF4] film due to the solubilization of acetone leading to a positive frequency shift in the QCM. Acetone was detected with a linear range from 7.05 to 750 ppmv. Sensitivity and limit of detection were found to be 3.49 Hz\/ppmv and 5.0 ppmv, respectively. The [bmim][BF4]-modified QCM sensor demonstrated anti-interference ability to commonly found volatile organic compounds in breath, e.g., isoprene, 1,2-pentadiene, d-limonene, and dl-limonene. This technology is useful for applications in non-invasive early diabetic diagnosis.<\/jats:p>","DOI":"10.3390\/s17010194","type":"journal-article","created":{"date-parts":[[2017,1,20]],"date-time":"2017-01-20T10:10:12Z","timestamp":1484907012000},"page":"194","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["1-Butyl-3-Methylimidazolium Tetrafluoroborate Film as a Highly Selective Sensing Material for Non-Invasive Detection of Acetone Using a Quartz Crystal Microbalance"],"prefix":"10.3390","volume":"17","author":[{"given":"Wenyan","family":"Tao","sequence":"first","affiliation":[{"name":"Shenzhen Key Laboratory of Special Functional Materials &amp; Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China"},{"name":"Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Lin","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Special Functional Materials &amp; Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sili","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, the Chinese University of Hong Kong, Shatin, Hong Kong 999077, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingji","family":"Xie","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410082, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanming","family":"Ke","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Special Functional Materials &amp; Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xierong","family":"Zeng","sequence":"additional","affiliation":[{"name":"Shenzhen Key Laboratory of Special Functional Materials &amp; Shenzhen Engineering Laboratory for Advance Technology of Ceramics, College of Materials Science and Engineering, Shenzhen University, Shenzhen 510081, China"},{"name":"Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,1,20]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchromb.2007.03.023","article-title":"Breath air analysis and its use as a biomarker in biological monitoring of occupational and environmental exposure to chemical agents","volume":"853","author":"Amorim","year":"2007","journal-title":"J. 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