{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:17:48Z","timestamp":1770509868852,"version":"3.49.0"},"reference-count":41,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T00:00:00Z","timestamp":1500336000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (FTIR), transmission electron microscopy (TEM), and electrochemical methods were utilized for the additional characterization of the membrane materials. The prepared electrode was utilized for the detection of guanine (G) and adenine (A). The anodic peak currents to G and A were linear in the concentrations ranging from 0.1 to 120 \u03bcM and 0.2 to 110 \u03bcM, respectively. The detection limits were found to be 0.1 \u03bcM and 0.2 \u03bcM, respectively. Moreover, the modified electrode could also be used to determine G and A in calf thymus DNA.<\/jats:p>","DOI":"10.3390\/s17071652","type":"journal-article","created":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T10:33:14Z","timestamp":1500373994000},"page":"1652","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode"],"prefix":"10.3390","volume":"17","author":[{"given":"Di","family":"Li","sequence":"first","affiliation":[{"name":"School of Life Sciences, Henan University, JinMing Road, Kaifeng 475000, China"}]},{"given":"Xiao-Lu","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Henan University, JinMing Road, Kaifeng 475000, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4489-6238","authenticated-orcid":false,"given":"Bao-Lin","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Henan University, JinMing Road, Kaifeng 475000, China"}]},{"given":"Fang-Yong","family":"Geng","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Henan University, JinMing Road, Kaifeng 475000, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6028-4103","authenticated-orcid":false,"given":"Jun","family":"Hong","sequence":"additional","affiliation":[{"name":"School of Life Sciences, Henan University, JinMing Road, Kaifeng 475000, China"},{"name":"Institute of Biotechnology, Henan University, Kaifeng 475000, China"}]},{"given":"Nader","family":"Sheibani","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences and Biomedical Engineering, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA"}]},{"given":"Ali","family":"Moosavi-Movahedi","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry and Biophysics, University of Tehran, Enquelab Avenue, Tehran 13145-1384, Iran"}]}],"member":"1968","published-online":{"date-parts":[[2017,7,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.fct.2013.05.054","article-title":"Anti-cancer effects of dioscin on three kinds of human lung cancer cell lines through inducing DNA damage and activating mitochondrial signal pathway","volume":"59","author":"Wei","year":"2013","journal-title":"Food Chem. 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