{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:16:40Z","timestamp":1760242600419,"version":"build-2065373602"},"reference-count":37,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T00:00:00Z","timestamp":1510876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>As the number of elderly persons with chronic illnesses increases, a new public infrastructure for their care is becoming increasingly necessary. In particular, technologies that can monitoring bio-signals in real-time have been receiving significant attention. Currently, most healthcare monitoring services are implemented by wireless carrier through centralized servers. These services are vulnerable to data concentration because all data are sent to a remote server. To solve these problems, we propose self-organizing P2P middleware for healthcare monitoring that enables a real-time multi bio-signal streaming without any central server by connecting the caregiver and care recipient. To verify the performance of the proposed middleware, we evaluated the monitoring service matching time based on a monitoring request. We also confirmed that it is possible to provide an effective monitoring service by evaluating the connectivity between Peer-to-Peer and average jitter.<\/jats:p>","DOI":"10.3390\/s17112650","type":"journal-article","created":{"date-parts":[[2017,11,17]],"date-time":"2017-11-17T12:00:20Z","timestamp":1510920020000},"page":"2650","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Self-Organizing Peer-To-Peer Middleware for Healthcare Monitoring in Real-Time"],"prefix":"10.3390","volume":"17","author":[{"given":"Hyun","family":"Kim","sequence":"first","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80 Daehakro, Bukgu, Daegu 702-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyeong","family":"Jo","sequence":"additional","affiliation":[{"name":"Center of Self-Organizing Software-Platform, Kyungpook National University, 80 Daehakro, Bukgu, Daegu 702-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8171-195X","authenticated-orcid":false,"given":"Soon","family":"Kang","sequence":"additional","affiliation":[{"name":"School of Electronics Engineering, College of IT Engineering, Kyungpook National University, 80 Daehakro, Bukgu, Daegu 702-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,11,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1109\/JIOT.2015.2417684","article-title":"An IoT-Aware Architecture for Smart Healthcare Systems","volume":"2","author":"Catarinucci","year":"2015","journal-title":"IEEE Int. Things J."},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Basanta, H., Huang, Y.P., and Lee, T.T. (2016, January 28\u201330). Intuitive IoT-based H2U healthcare system for elderly people. Proceedings of the 2016 13th IEEE International Conference on Networking, Sensing, and Control (ICNSC), Mexico City, Mexico.","DOI":"10.1109\/ICNSC.2016.7479018"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1109\/MCOM.2017.1600374CM","article-title":"Federated Internet of Things and Cloud Computing Pervasive Patient Health Monitoring System","volume":"55","author":"Abawajy","year":"2017","journal-title":"IEEE Commun. Mag."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"5702","DOI":"10.3390\/s140305702","article-title":"Fully Distributed Monitoring Architecture Supporting Multiple Trackees and Trackers in Indoor Mobile Asset Management Application","volume":"14","author":"Jeong","year":"2014","journal-title":"Sensors"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"12156","DOI":"10.3390\/s150612156","article-title":"Self-Organizing Distributed Architecture Supporting Dynamic Space Expanding and Reducing in Indoor LBS Environment","volume":"15","author":"Jeong","year":"2015","journal-title":"Sensors"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Jo, H., Son, T., Jeong, S., and Kang, S. (2016). Proximity-Based Asynchronous Messaging Platform for Location-Based Internet of Things Service. ISPRS Int. J. Geo-Inf., 5.","DOI":"10.3390\/ijgi5070116"},{"key":"ref_7","unstructured":"Srisuresh, P., and Egevang, K. (2017, November 17). Traditional IP Network Address Translator (Traditional NAT). Available online: https:\/\/tools.ietf.org\/html\/rfc3022."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.sysarc.2014.01.008","article-title":"Remote service discovery and binding architecture for soft real-time QoS in indoor location-based service","volume":"60","author":"Jeong","year":"2014","journal-title":"J. Syst. Archit."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Srisuresh, P., Tsirtsis, G., Akkiraju, P., and Heffernan, A. (1999). DNS Extensions to Network Address Translators (DNS_ALG), The Internet Society.","DOI":"10.17487\/rfc2694"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Tran Thi Thu, H., Park, J., Won, Y., and Kim, J. (2014, January 28\u201330). Combining STUN Protocol and UDP Hole Punching Technique for Peer-To-Peer Communication across Network Address Translation. Proceedings of the 2014 IEEE International Conference on IT Convergence and Security (ICITCS), Beijing, China.","DOI":"10.1109\/ICITCS.2014.7021753"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"McKay, R.I., Shin, J., Hoang, T.H., Nguyen, X.H., and Mori, N. (2007, January 25\u201328). Using compression to understand the distribution of building blocks in genetic programming populations. Proceedings of the 2007 IEEE Congress on Evolutionary Computation, CEC 2007, Singapore.","DOI":"10.1109\/CEC.2007.4424785"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Srirama, S.N., and Liyanage, M. (2014, January 27\u201329). TCP Hole Punching Approach to Address Devices in Mobile Networks. Proceedings of the 2014 International Conference on Future Internet of Things and Cloud, Barcelona, Spain.","DOI":"10.1109\/FiCloud.2014.24"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1109\/ACCESS.2015.2437951","article-title":"The Internet of Things for Health Care: A Comprehensive Survey","volume":"3","author":"Kwak","year":"2015","journal-title":"IEEE Access"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.future.2017.04.036","article-title":"Towards fog-driven IoT eHealth: Promises and challenges of IoT in medicine and healthcare","volume":"78","author":"Farahani","year":"2018","journal-title":"Future Gener. Comput. Syst."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Wang, C., Wang, Q., and Shi, S. (2012, January 13\u201316). A distributed wireless body area network for medical supervision. Proceedings of the 2012 IEEE International Instrumentation and Measurement Technology Conference, Graz, Austria.","DOI":"10.1109\/I2MTC.2012.6229260"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11227-013-1021-9","article-title":"Wireless sensor networks: A survey on recent developments and potential synergies","volume":"68","author":"Rawat","year":"2014","journal-title":"J. Supercomput."},{"key":"ref_17","first-page":"210","article-title":"Real Time Monitoring of Human Body Vital Signs using Bluetooth and WLAN","volume":"7","author":"Khan","year":"2016","journal-title":"Int. J. Adv. Comput. Sci. Appl."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Laine, T.H., Lee, C., and Suk, H. (2014, January 2\u20134). Mobile Gateway for Ubiquitous Health Care System Using ZigBee and Bluetooth. Proceedings of the 2014 Eighth International Conference on Innovative Mobile and Internet Services in Ubiquitous Computing, Birmingham, UK.","DOI":"10.1109\/IMIS.2014.17"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Passow, P., Stoll, N., Junginger, S., and Thurow, K. (2013, January 6\u20139). A wireless sensor node for long-term monitoring in life science applications. Proceedings of the 2013 IEEE International Instrumentation and Measurement Technology Conference (I2MTC), Minneapolis, MN, USA.","DOI":"10.1109\/I2MTC.2013.6555545"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Rahmani, A.M., Thanigaivelan, N.K., Gia, T.N., Granados, J., Negash, B., Liljeberg, P., and Tenhunen, H. (2015, January 9\u201312). Smart e-Health Gateway: Bringing intelligence to Internet-of-Things based ubiquitous healthcare systems. Proceedings of the 12th Annual IEEE Consumer Communications and Networking Conference (CCNC), Las Vegas, NV, USA.","DOI":"10.1109\/CCNC.2015.7158084"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Shivakumar, N.S., and Sasikala, M. (2014, January 6\u20138). Design of vital sign monitor based on wireless sensor networks and telemedicine technology. Proceedings of the 2014 International Conference on Green Computing Communication and Electrical Engineering (ICGCCEE), Coimbatore, India.","DOI":"10.1109\/ICGCCEE.2014.6922257"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Mora, H., Gil, D., Terol, R.M., Azor\u00edn, J., and Szymanski, J. (2017). An IoT-Based Computational Framework for Healthcare Monitoring in Mobile Environments. Sensors, 17.","DOI":"10.3390\/s17102302"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.irbm.2015.01.009","article-title":"Review of current telemedicine applications for chronic diseases. Toward a more integrated system?","volume":"36","author":"Finet","year":"2015","journal-title":"IRBM"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.comnet.2016.01.009","article-title":"Cloud-assisted Industrial Internet of Things (IIoT)\u2014Enabled framework for health monitoring","volume":"101","author":"Hossain","year":"2016","journal-title":"Comput. Netw."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1109\/TIM.2012.2218681","article-title":"Sensing devices and sensor signal processing for remote monitoring of vital signs in CHF patients","volume":"62","author":"Fanucci","year":"2013","journal-title":"IEEE Trans. Instrum. Meas."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Lim, S., Oh, T.H., Choi, Y.B., and Lakshman, T. (2010, January 7\u20139). Security Issues on Wireless Body Area Network for Remote Healthcare Monitoring. Proceedings of the 2010 IEEE International Conference on Sensor Networks, Ubiquitous, and Trustworthy Computing, Newport Beach, CA, USA.","DOI":"10.1109\/SUTC.2010.61"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Rushanan, M., Rubin, A.D., Kune, D.F., and Swanson, C.M. (2014, January 18\u201321). SoK: Security and Privacy in Implantable Medical Devices and Body Area Networks. Proceedings of the 2014 IEEE Symposium on Security and Privacy, San Jose, CA, USA.","DOI":"10.1109\/SP.2014.40"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Ondiege, B., Clarke, M., and Mapp, G. (2017). Exploring a New Security Framework for Remote Patient Monitoring Devices. Computers, 6.","DOI":"10.3390\/computers6010011"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3390\/s120100055","article-title":"Security Issues in Healthcare Applications Using Wireless Medical Sensor Networks: A Survey","volume":"12","author":"Kumar","year":"2012","journal-title":"Sensors"},{"key":"ref_30","first-page":"1","article-title":"Self-Organizing Wearable Device Platform for Assisting and Reminding Humans in Real Time","volume":"2016","author":"Park","year":"2016","journal-title":"Mob. Inf. Syst."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/2543581.2543583","article-title":"XL peer-to-peer pub\/sub systems","volume":"46","author":"Kermarrec","year":"2013","journal-title":"ACM Comput. Surv."},{"key":"ref_32","doi-asserted-by":"crossref","unstructured":"Wadhwa, R., Mehra, A., Singh, P., and Singh, M. (2015, January 6\u201310). A pub\/sub based architecture to support public healthcare data exchange. Proceedings of the 2015 7th International Conference on Communication Systems and Networks (COMSNETS), Bangalore, India.","DOI":"10.1109\/COMSNETS.2015.7098706"},{"key":"ref_33","unstructured":"Hintjens, P. (2013). ZeroMQ: Messaging for Many Applications, O\u2019Reilly Media, Inc."},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Khattak, H.A., Ruta, M., and Di Sciascio, E. (2014, January 14\u201318). CoAP-based healthcare sensor networks: A survey. Proceedings of the 2014 11th International Bhurban Conference on Applied Sciences & Technology (IBCAST), Islamabad, Pakistan.","DOI":"10.1109\/IBCAST.2014.6778196"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Ghamari, M., Janko, B., Sherratt, R., Harwin, W., Piechockic, R., and Soltanpur, C. (2016). A Survey on Wireless Body Area Networks for eHealthcare Systems in Residential Environments. Sensors, 16.","DOI":"10.3390\/s16060831"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Kim, B.-S., Kim, K., and Kim, K.-I. (2017). A Survey on Mobility Support in Wireless Body Area Networks. Sensors, 17.","DOI":"10.3390\/s17040797"},{"key":"ref_37","first-page":"8","article-title":"A Traffic Prediction Model for Self-Adapting Routing Overlay Network in Publish\/Subscribe System","volume":"2017","author":"Chi","year":"2017","journal-title":"Mob. Inf. Syst."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/17\/11\/2650\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:50:00Z","timestamp":1760208600000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/17\/11\/2650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,17]]},"references-count":37,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2017,11]]}},"alternative-id":["s17112650"],"URL":"https:\/\/doi.org\/10.3390\/s17112650","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2017,11,17]]}}}