{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T00:13:02Z","timestamp":1770509582004,"version":"3.49.0"},"reference-count":146,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T00:00:00Z","timestamp":1511222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21475088"],"award-info":[{"award-number":["21475088"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["14ZR1430200"],"award-info":[{"award-number":["14ZR1430200"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Surface-enhanced Raman spectroscopy (SERS) is a powerful technique for the discrimination, identification, and potential quantification of certain compounds\/organisms. However, its real application is challenging due to the multiple interference from the complicated detection matrix. Therefore, selective\/specific detection is crucial for the real application of SERS technique. We summarize in this review five selective\/specific detection techniques (chemical reaction, antibody, aptamer, molecularly imprinted polymers and microfluidics), which can be applied for the rapid and reliable selective\/specific detection when coupled with SERS technique.<\/jats:p>","DOI":"10.3390\/s17112689","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T11:23:20Z","timestamp":1511263400000},"page":"2689","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Selectivity\/Specificity Improvement Strategies in Surface-Enhanced Raman Spectroscopy Analysis"],"prefix":"10.3390","volume":"17","author":[{"given":"Feng","family":"Wang","sequence":"first","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]},{"given":"Shiyu","family":"Cao","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]},{"given":"Ruxia","family":"Yan","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]},{"given":"Zewei","family":"Wang","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3017-4215","authenticated-orcid":false,"given":"Haifeng","family":"Yang","sequence":"additional","affiliation":[{"name":"The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China"}]}],"member":"1968","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.tifs.2016.05.020","article-title":"Determination of chemical hazards in foods using surface-enhanced raman spectroscopy coupled with advanced separation techniques","volume":"54","author":"Liao","year":"2016","journal-title":"Trends Food Sci. 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