{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:30:06Z","timestamp":1779917406851,"version":"3.53.1"},"reference-count":140,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2017,12,31]],"date-time":"2017-12-31T00:00:00Z","timestamp":1514678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>From active developments and applications of various devices to acquire outside and inside information and to operate based on feedback from that information, the sensor market is growing rapidly. In accordance to this trend, the surface plasmon resonance (SPR) sensor, an optical sensor, has been actively developed for high-sensitivity real-time detection. In this study, the fundamentals of SPR sensors and recent approaches for enhancing sensing performance are reported. In the section on the fundamentals of SPR sensors, a brief description of surface plasmon phenomena, SPR, SPR-based sensing applications, and several configuration types of SPR sensors are introduced. In addition, advanced nanotechnology- and nanofabrication-based techniques for improving the sensing performance of SPR sensors are proposed: (1) localized SPR (LSPR) using nanostructures or nanoparticles; (2) long-range SPR (LRSPR); and (3) double-metal-layer SPR sensors for additional performance improvements. Consequently, a high-sensitivity, high-biocompatibility SPR sensor method is suggested. Moreover, we briefly describe issues (miniaturization and communication technology integration) for future SPR sensors.<\/jats:p>","DOI":"10.3390\/s18010098","type":"journal-article","created":{"date-parts":[[2018,1,3]],"date-time":"2018-01-03T12:00:06Z","timestamp":1514980806000},"page":"98","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["A Localized Surface Plasmon Resonance Sensor Using Double-Metal-Complex Nanostructures and a Review of Recent Approaches"],"prefix":"10.3390","volume":"18","author":[{"given":"Heesang","family":"Ahn","sequence":"first","affiliation":[{"name":"Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyerin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6645-6399","authenticated-orcid":false,"given":"Jong-ryul","family":"Choi","sequence":"additional","affiliation":[{"name":"Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu 41061, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyujung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Korea"},{"name":"Department of Optics and Mechatronics Engineering, Pusan National University, Busan 46241, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2017,12,31]]},"reference":[{"key":"ref_1","unstructured":"Roessig, T.A., Howe, R.T., Pisano, A.P., and Smith, J.H. 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