{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:27:14Z","timestamp":1777591634222,"version":"3.51.4"},"reference-count":23,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T00:00:00Z","timestamp":1529625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Natural Science Foundation of China under Grants","award":["61433010"],"award-info":[{"award-number":["61433010"]}]},{"name":"National Natural Science Foundation of China under Grants","award":["61520106011"],"award-info":[{"award-number":["61520106011"]}]},{"name":"the Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan","award":["JP23106005"],"award-info":[{"award-number":["JP23106005"]}]},{"name":"the Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan","award":["JP16H06076"],"award-info":[{"award-number":["JP16H06076"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The demand for a harmless noncontact trapping and transportation method in manipulation and measurement of biological micro objects waits to be met. In this paper, a novel micromanipulation method named \u201cHydrodynamic Tweezers\u201d using the vortex induced by oscillating a single piezoelectric actuator is introduced. The piezoelectric actuator is set between a micropipette and a copper beam. Oscillating the actuator at a certain frequency causes the resonance of the copper beam and extend 1D straight oscillation of the piezoelectric actuator to 2D circular oscillation of the micropipette, which induces a micro vortex after putting the micropipette into fluid. The induced vortex featuring low pressure in its core area can trap the object nearby. A robotic micromanipulator is utilized to transport the trapped objects together with the micropipette. Experiments of trapping and transportation microbeads are carried out to characterize the key parameters. The results show that the trapping force can be controlled by adjusting peak-peak voltage of the sinusoidal voltage input into the piezoelectric actuator.<\/jats:p>","DOI":"10.3390\/s18072002","type":"journal-article","created":{"date-parts":[[2018,6,22]],"date-time":"2018-06-22T10:56:28Z","timestamp":1529664988000},"page":"2002","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Hydrodynamic Tweezers: Trapping and Transportation in Microscale Using Vortex Induced by Oscillation of a Single Piezoelectric Actuator"],"prefix":"10.3390","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0230-2742","authenticated-orcid":false,"given":"Xiaoming","family":"Liu","sequence":"first","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuqing","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Systems Innovation, Osaka University, Osaka 560-8531, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Mae","sequence":"additional","affiliation":[{"name":"Department of Systems Innovation, Osaka University, Osaka 560-8531, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshio","family":"Fukuda","sequence":"additional","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Arai","sequence":"additional","affiliation":[{"name":"School of Mechatronical Engineering, Beijing Institute of Technology, Beijing 100081, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,22]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.tibtech.2010.03.002","article-title":"Single cell analysis: The new frontier in \u2018omics\u2019","volume":"28","author":"Wang","year":"2010","journal-title":"Trends Biotechnol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"31566","DOI":"10.3390\/s151229872","article-title":"Multidirectional image sensing for microscopy based on a rotatable robot","volume":"15","author":"Shen","year":"2015","journal-title":"Sensors"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3390\/mi5030681","article-title":"A Single Cell Extraction Chip Using Vibration-Induced Whirling Flow and a Thermo-Responsive Gel Pattern","volume":"5","author":"Hayakawa","year":"2014","journal-title":"Micromachines"},{"key":"ref_4","first-page":"1","article-title":"Automatic sample alignment under microscopy for 360\u00b0 imaging based on the nanorobotic manipulation system","volume":"99","author":"Shen","year":"2017","journal-title":"IEEE Trans. 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