{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T06:18:25Z","timestamp":1790489905591,"version":"4.1.0"},"reference-count":30,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T00:00:00Z","timestamp":1530057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61605179"],"award-info":[{"award-number":["61605179"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Fundamental Research Funds for the Central Universities","award":["162301132703, G1323511665"],"award-info":[{"award-number":["162301132703, G1323511665"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this work, a surface plasmon resonance (SPR) biosensor based on two-dimensional transition metal dichalcogenides (TMDCs) is proposed to improve the biosensor\u2019s sensitivity. In this sensor, different kinds of two-dimensional TMDCs are coated on both surfaces of metal film. By optimizing the structural parameters, the angular sensitivity can reach as high as 315.5 Deg\/RIU with 7-layers WS2 and 36 nm Al thin film, which is 3.3 times of the conventional structure based on single Al thin film. We also obtain maximum phase sensitivity (3.85 \u00d7 106 Deg\/RIU) with bilayer WS2 and 35 nm Al thin film. The phase sensitivity can be further improved by employing Ag and removing air layer. The proposed configuration is of great potential for biochemical sensing.<\/jats:p>","DOI":"10.3390\/s18072056","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T11:02:05Z","timestamp":1530097325000},"page":"2056","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":91,"title":["Sensitivity Enhancement in Surface Plasmon Resonance Biochemical Sensor Based on Transition Metal Dichalcogenides\/Graphene Heterostructure"],"prefix":"10.3390","volume":"18","author":[{"given":"Xiang","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9754-9873","authenticated-orcid":false,"given":"Tianye","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry Shum","family":"Ping","sequence":"additional","affiliation":[{"name":"Center of Fiber Technology, School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxing","family":"Pan","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiheng","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering and Electronic Information, China University of Geosciences (Wuhan), Wuhan 430074, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,27]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1007\/BF01391532","article-title":"Excitation of nonradiative surface plasma waves in silver by method of frustrated total reflection","volume":"216","author":"Otto","year":"1968","journal-title":"Zeitschrift f\u00fcr Physik a Hadrons and Nuclei"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1515\/zna-1968-1247","article-title":"Notizen: Radiative decay of nonradiative surface plasmons excited by light","volume":"23","author":"Kretschmann","year":"1968","journal-title":"Zeitschrift f\u00fcr Naturforschung A"},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Ahn, H., Song, H., Choi, J.R., and Kim, K. 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