{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:45:05Z","timestamp":1760197505630,"version":"build-2065373602"},"reference-count":71,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T00:00:00Z","timestamp":1530144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21727804, 21573208, 21573210, 20903002"],"award-info":[{"award-number":["21727804, 21573208, 21573210, 20903002"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Basic Research Special Foundation","award":["2013CB834602, NKBRSF"],"award-info":[{"award-number":["2013CB834602, NKBRSF"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Vibrational spectroscopy is a powerful tool for probing molecular structures and dynamics since it offers a unique fingerprint that allows molecular identification. One of important aspects of applying vibrational spectroscopy is to develop the probes that can characterize the related properties of molecules such as the conformation and intermolecular interaction. Many examples of vibrational probes have appeared in the literature, including the azide group (\u2013N3), amide group (\u2013CONH2), nitrile groups (\u2013CN), hydroxyl group (\u2013OH), \u2013CH group and so on. Among these probes, the \u2013CH group is an excellent one since it is ubiquitous in organic and biological molecules and the C\u2013H stretching vibrational spectrum is extraordinarily sensitive to the local molecular environment. However, one challenge encountered in the application of C\u2013H probes arises from the difficulty in the accurate assignment due to spectral congestion in the C\u2013H stretching region. In this paper, recent advances in the complete assignment of C\u2013H stretching spectra of aliphatic alcohols and the utility of C\u2013H vibration as a probe of the conformation and weak intermolecular interaction are outlined. These results fully demonstrated the potential of the \u2013CH chemical group as a molecular probe.<\/jats:p>","DOI":"10.3390\/s18072061","type":"journal-article","created":{"date-parts":[[2018,6,28]],"date-time":"2018-06-28T10:53:33Z","timestamp":1530183213000},"page":"2061","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Probe of Alcohol Structures in the Gas and Liquid States Using C\u2013H Stretching Raman Spectroscopy"],"prefix":"10.3390","volume":"18","author":[{"given":"Yuanqin","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Physics, Anhui University, Hefei 230601, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Fan","sequence":"additional","affiliation":[{"name":"Hefei National Laboratory for Physical Sciences at the Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Chemical Physics, University of Science and Technology of China, Hefei 230026, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxi","family":"Wang","sequence":"additional","affiliation":[{"name":"Hefei National Laboratory for Physical Sciences at the Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Chemical Physics, University of Science and Technology of China, Hefei 230026, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoguo","family":"Zhou","sequence":"additional","affiliation":[{"name":"Hefei National Laboratory for Physical Sciences at the Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Chemical Physics, University of Science and Technology of China, Hefei 230026, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Physics, Anhui University, Hefei 230601, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilin","family":"Liu","sequence":"additional","affiliation":[{"name":"Hefei National Laboratory for Physical Sciences at the Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Chemical Physics, University of Science and Technology of China, Hefei 230026, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/jbio.200910041","article-title":"Label-free biochemical characterization of stem cells using vibrational spectroscopy","volume":"2","author":"Chan","year":"2009","journal-title":"J. Biophotonics"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Sandfort, V., Trabold, B.M., Abdolvand, A., Bolwien, C., Russell, P.S.J., Wollenstein, J., and Palzer, S. (2017). Monitoring the Wobbe Index of Natural Gas Using Fiber-Enhanced Raman Spectroscopy. Sensors, 17.","DOI":"10.3390\/s17122714"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.vibspec.2011.08.003","article-title":"Raman spectroscopy: Recent advancements, techniques and applications","volume":"57","author":"Das","year":"2011","journal-title":"Vib. Spectrosc."},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Mars, K., Lioe, D.X., Kawahito, S., Yasutomi, K., Kagawa, K., Yamada, T., and Hashimoto, M. (2017). Label-Free Biomedical Imaging Using High-Speed Lock-In Pixel Sensor for Stimulated Raman Scattering. Sensors, 17.","DOI":"10.3390\/s17112581"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1002\/jrs.5173","article-title":"Review of optical fibre probes for enhanced Raman sensing","volume":"48","author":"Wang","year":"2017","journal-title":"J. Raman Spectrosc."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Dhakal, S., Chao, K.L., Huang, Q., Kim, M., Schmidt, W., Qin, J.W., and Broadhurst, C.L. (2018). A Simple Surface-Enhanced Raman Spectroscopic Method for on-Site Screening of Tetracycline Residue in Whole Milk. Sensors, 18.","DOI":"10.3390\/s18020424"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Tran, M., Whale, A., and Padalkar, S. (2018). Exploring the Efficacy of Platinum and Palladium Nanostructures for Organic Molecule Detection via Raman Spectroscopy. Sensors, 18.","DOI":"10.3390\/s18010147"},{"key":"ref_8","first-page":"341","article-title":"Raman and mid-infrared spectroscopic imaging: Applications and advancements","volume":"108","author":"Gautam","year":"2015","journal-title":"Curr. Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"15267","DOI":"10.1021\/jp808515t","article-title":"Peptide C\u03b1D\u03b1 Stretch Frequencies in a Hydrated Conformation Are Perturbed Mainly by C\u03b1-D\u03b1\u00b7\u00b7\u00b7O Hydrogen Bonding","volume":"112","author":"Mirkin","year":"2008","journal-title":"J. Phys. Chem. B"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"125103","DOI":"10.1063\/1.3100185","article-title":"Carbon-deuterium vibrational probes of peptide conformation: Alanine dipeptide and glycine dipeptide","volume":"130","author":"Miller","year":"2009","journal-title":"J. Chem. Phys."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"8565","DOI":"10.1021\/jp1028596","article-title":"Carbon-Deuterium Vibrational Probes of the Protonation State of Histidine in the Gas-Phase and in Aqueous Solution","volume":"114","author":"Miller","year":"2010","journal-title":"J. Phys. Chem. B"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/bip.21523","article-title":"Conformation Dependence of the (CD alpha)-D-alpha Stretch Mode in Peptides: Side-Chain Influence in Dipeptide Structures","volume":"93","author":"Mirkin","year":"2010","journal-title":"Biopolymers"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"7991","DOI":"10.1021\/jp900516c","article-title":"Efforts toward Developing Probes of Protein Dynamics: Vibrational Dephasing and Relaxation of Carbon-Deuterium Stretching Modes in Deuterated Leucine","volume":"113","author":"Zimmermann","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"8119","DOI":"10.1039\/b908588b","article-title":"Nitrile groups as vibrational probes of biomolecular structure and dynamics: An overview","volume":"11","author":"Lindquist","year":"2009","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"6098","DOI":"10.1039\/c0cp01087a","article-title":"2D IR Spectroscopy of the C-D stretching vibration of the deuterated formic acid dimer","volume":"13","author":"Nydegger","year":"2011","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1021\/jz201161b","article-title":"Site-Specific Spectroscopic Reporters of the Local Electric Field, Hydration, Structure, and Dynamics of Biomolecules","volume":"2","author":"Waegele","year":"2011","journal-title":"J. Phys. Chem. Lett."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5827","DOI":"10.1002\/anie.201400328","article-title":"Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules","volume":"53","author":"Hong","year":"2014","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/nmeth.2878","article-title":"Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering","volume":"11","author":"Wei","year":"2014","journal-title":"Nat. Methods"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"10167","DOI":"10.1021\/acs.jpcb.6b04319","article-title":"Isonitrile as an Ultrasensitive Infrared Reporter of Hydrogen-Bonding Structure and Dynamics","volume":"120","author":"Maj","year":"2016","journal-title":"J. Phys. Chem. B"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1021\/acs.chemrev.6b00625","article-title":"Transparent Window Vibrational Probes for the Characterization of Proteins with High Structural and Temporal Resolution","volume":"117","author":"Adhikary","year":"2017","journal-title":"Chem. Rev."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1021\/acs.accounts.7b00002","article-title":"Vibrational Probes: From Small Molecule Solvatochromism Theory and Experiments to Applications in Complex Systems","volume":"50","author":"Blasiak","year":"2017","journal-title":"Acc. Chem. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1002\/jrs.5182","article-title":"Raman probing of lipids, proteins, and mitochondria in skeletal myocytes: A case study on obesity","volume":"48","author":"Brazhe","year":"2017","journal-title":"J. Raman Spectrosc."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"13991","DOI":"10.1021\/jp804900u","article-title":"Optimized Quantum Mechanics\/Molecular Mechanics Strategies for Nitrile Vibrational Probes: Acetonitrile and para-Tolunitrile in Water and Tetrahydrofuran","volume":"112","author":"Lindquist","year":"2008","journal-title":"J. Phys. Chem. B"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"19420","DOI":"10.1039\/C7CP01867C","article-title":"The covalently bound diazo group as an infrared probe for hydrogen bonding environments","volume":"19","author":"You","year":"2017","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1039\/C7CP07160D","article-title":"7-Cyanoindole fluorescence as a local hydration reporter: Application to probe the microheterogeneity of nine water-organic binary mixtures","volume":"20","author":"Mukherjee","year":"2018","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"7027","DOI":"10.1039\/C5CP04413H","article-title":"C equivalent to N stretching vibration of 5-cyanotryptophan as an infrared probe of protein local environment: What determines its frequency?","volume":"18","author":"Zhang","year":"2016","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"18094","DOI":"10.1039\/C6CP01578F","article-title":"Vibrational solvatochromism of nitrile infrared probes: Beyond the vibrational Stark dipole approach","volume":"18","author":"Blasiak","year":"2016","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1126\/science.1071293","article-title":"Watching vibrational energy transfer in liquids with atomic spatial resolution","volume":"296","author":"Wang","year":"2002","journal-title":"Science"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"8716","DOI":"10.1021\/jp067062h","article-title":"Vibrational spectra and molecular orientation with experimental configuration analysis in surface sum frequency generation (SFG)","volume":"111","author":"Gan","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev-physchem-040214-121322","article-title":"Quantitative Sum-Frequency Generation Vibrational Spectroscopy of Molecular Surfaces and Interfaces: Lineshape, Polarization, and Orientation","volume":"Volume 66","author":"Johnson","year":"2015","journal-title":"Annual Review of Physical Chemistry"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"9798","DOI":"10.1021\/jp512798f","article-title":"In Situ Studies on the Dissociation and Photocatalytic Reactions of CH3OH on TiO2 Thin Film by Sum Frequency Generation Vibrational Spectroscopy","volume":"119","author":"Feng","year":"2015","journal-title":"J. Phys. Chem. C"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"23486","DOI":"10.1021\/acs.jpcc.5b06598","article-title":"Spectral Identification of Methanol on TiO2 Surfaces with Sum Frequency Generation in the C\u2013H Stretching Region","volume":"119","author":"Liu","year":"2015","journal-title":"J. Phys. Chem. C"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"5516","DOI":"10.1021\/ja060156k","article-title":"Probing molecular structure at interfaces for comparison with bulk solution behavior: Water\/2-propanol mixtures monitored by vibrational sum frequency spectroscopy","volume":"128","author":"Kataoka","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1021\/acs.jpcc.5b00278","article-title":"Orientational Time Correlation Functions for Vibrational Sum-Frequency Generation. 3. Methanol","volume":"119","author":"Liu","year":"2015","journal-title":"J. Phys. Chem. C"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"7962","DOI":"10.1039\/C7SM00813A","article-title":"The behavior of hydroxide and hydronium ions at the hexadecane-water interface studied with second harmonic generation and zeta potential measurements","volume":"13","author":"Gan","year":"2017","journal-title":"Soft Matter"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/j.bpj.2017.04.026","article-title":"Effect of Ca2+ to Sphingomyelin Investigated by Sum Frequency Generation Vibrational Spectroscopy","volume":"112","author":"Feng","year":"2017","journal-title":"Biophys. J."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"244707","DOI":"10.1063\/1.4972564","article-title":"Spectral assignment and orientational analysis in a vibrational sum frequency generation study of DPPC monolayers at the air\/water interface","volume":"145","author":"Feng","year":"2016","journal-title":"J. Chem. Phys."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"4488","DOI":"10.1039\/C6CP07827C","article-title":"Molecular interactions of organic molecules at the air\/water interface investigated by sum frequency generation vibrational spectroscopy","volume":"19","author":"Wang","year":"2017","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_39","first-page":"E3888","article-title":"Facet-specific interaction between methanol and TiO2 probed by sum-frequency vibrational spectroscopy","volume":"115","author":"Yang","year":"2018","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"12970","DOI":"10.1021\/acs.jpcb.5b06563","article-title":"Differentiation of Rubidiated Methyl-d-Glycoside Stereoisomers by Infrared Multiple-Photon Dissociation Spectroscopy in the O\u2013H and C\u2013H Stretching Regions","volume":"119","author":"Pearson","year":"2015","journal-title":"J. Phys. Chem. B"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3847\/1538-4357\/aa5fa9","article-title":"Polycyclic Aromatic Hydrocarbons with Aliphatic Sidegroups: Intensity Scaling for the C\u2013H Stretching Modes and Astrophysical Implications","volume":"837","author":"Yang","year":"2017","journal-title":"Astrophys. J."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"8236","DOI":"10.1021\/jp5014048","article-title":"A First-Principles Model of Fermi Resonance in the Alkyl CH Stretch Region: Application to Hydronaphthalenes, Indanes, and Cyclohexane","volume":"118","author":"Sibert","year":"2014","journal-title":"J. Phys. Chem. B"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"5305","DOI":"10.1039\/C7SC02027A","article-title":"Identifying the first folded alkylbenzene via ultraviolet, infrared, and Raman spectroscopy of pentylbenzene through decylbenzene","volume":"8","author":"Hewett","year":"2017","journal-title":"Chem. Sci."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"5296","DOI":"10.1021\/acs.jpclett.7b02276","article-title":"Infrared-Enhanced Fluorescence-Gain Spectroscopy: Conformation-Specific Excited-State Infrared Spectra of Alkylbenzenes","volume":"8","author":"Hewett","year":"2017","journal-title":"J. Phys. Chem. Lett."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"6687","DOI":"10.1021\/acs.jpca.7b05320","article-title":"Theoretical Investigation of C\u2013H Vibrational Spectroscopy. 1. Modeling of Methyl and Methylene Groups of Ethanol with Different Conformers","volume":"121","author":"Wang","year":"2017","journal-title":"J. Phys. Chem. A"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1021\/acs.jpcb.5b03323","article-title":"Infrared and Raman Spectroscopy from Ab Initio Molecular Dynamics and Static Normal Mode Analysis: The C\u2013H Region of DMSO as a Case Study","volume":"120","author":"Fischer","year":"2016","journal-title":"J. Phys. Chem. B"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"7442","DOI":"10.1021\/jp4014674","article-title":"Spectroscopy of the C\u2013H Stretching Vibrational Band in Selected Organic Molecules","volume":"117","author":"Sebek","year":"2013","journal-title":"J. Phys. Chem. A"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"154306","DOI":"10.1063\/1.2357953","article-title":"Infrared plus vacuum ultraviolet spectroscopy of neutral and ionic methanol monomers and clusters: New experimental results","volume":"125","author":"Hu","year":"2006","journal-title":"J. Chem. Phys."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.cplett.2006.03.084","article-title":"Identification of overlapping features in the sum frequency generation vibrational spectra of air\/ethanol interface","volume":"423","author":"Gan","year":"2006","journal-title":"Chem. Phys. Lett."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"8971","DOI":"10.1021\/jp0675781","article-title":"New C\u2013H stretching vibrational spectral features in the Raman spectra of gaseous and liquid ethanol","volume":"111","author":"Yu","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/jrs.4446","article-title":"Overlapping spectral features and new assignment of 2-propanol in the C\u2013H stretching region","volume":"45","author":"Yu","year":"2014","journal-title":"J. Raman Spectrosc."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1021\/jp400886y","article-title":"Complete Raman Spectral Assignment of Methanol in the C\u2013H Stretching Region","volume":"117","author":"Yu","year":"2013","journal-title":"J. Phys. Chem. A"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1002\/jrs.5000","article-title":"New spectral assignment of n-propanol in the C\u2013H stretching region","volume":"47","author":"Yu","year":"2016","journal-title":"J. Raman Spectrosc."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1021\/jp0356463","article-title":"Surface characterization of nanoscale TiO2 film by sum frequency generation using methanol as a molecular probe","volume":"108","author":"Wang","year":"2004","journal-title":"J. Phys. Chem. B"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0022-2860(01)00762-1","article-title":"Anharmonic Interactions and Fermi Resonance in the Vibrational Spectra of Alcohols","volume":"605","author":"Atamas","year":"2002","journal-title":"J. Mol. Struct."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"6343","DOI":"10.1021\/jp027364t","article-title":"Surface studies of aqueous methanol solutions by vibrational broad bandwidth sum frequency generation spectroscopy","volume":"107","author":"Ma","year":"2003","journal-title":"J. Phys. Chem. B"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1063\/1.90707","article-title":"Photoacoustic Raman-Spectroscopy (PARS) Using cw Laser Sources","volume":"34","author":"Barrett","year":"1979","journal-title":"Appl. Phys. Lett."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/jrs.1754","article-title":"Precise measurement of the depolarization ratio from photoacoustic Raman spectroscopy","volume":"38","author":"Yu","year":"2007","journal-title":"J. Raman Spectrosc."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"10660","DOI":"10.1021\/acs.jpcb.6b07900","article-title":"Multistate Mechanism of Lysozyme Denaturation through Synchronous Analysis of Raman Spectra","volume":"120","author":"Xing","year":"2016","journal-title":"J. Phys. Chem. B"},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1002\/jrs.4940","article-title":"Ratiometric detection of Raman hydration shell spectra","volume":"47","author":"Wang","year":"2016","journal-title":"J. Raman Spectrosc."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/jrs.2997","article-title":"Reorientation dynamics in liquid alcohols from Raman spectroscopy","volume":"43","author":"Lin","year":"2012","journal-title":"J. Raman Spectrosc."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1063\/1.443996","article-title":"The Motional Collapse of the Methyl C\u2013H Stretching Vibration Bands","volume":"77","author":"Macphail","year":"1982","journal-title":"J. Chem. Phys."},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1021\/jp983629l","article-title":"C\u2013H stretch modes as a probe of H-bonding in methanol-containing clusters","volume":"103","author":"Gruenloh","year":"1999","journal-title":"J. Phys. Chem. A"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.1021\/jp8092034","article-title":"Improper Hydrogen-Bonding CH\u00b7Y Interactions in Binary Methanol Systems as Studied by FTIR and Raman Spectroscopy","volume":"113","author":"Keefe","year":"2009","journal-title":"J. Phys. Chem. A"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"214502","DOI":"10.1063\/1.2128671","article-title":"Pressure tuning of the Fermi resonance in liquid methanol: Implications for the analysis of high-pressure vibrational spectroscopy experiments","volume":"123","author":"Arencibia","year":"2005","journal-title":"J. Chem. Phys."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"20051","DOI":"10.1073\/pnas.1310414110","article-title":"Both the cis-trans equilibrium and isomerization dynamics of a single proline amide modulate \u03b22-microglobulin amyloid assembly","volume":"110","author":"Torbeev","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"10563","DOI":"10.1039\/C6CP00244G","article-title":"C\u03b2-H stretching vibration as a new probe for conformation of n-propanol in gaseous and liquid states","volume":"18","author":"Yu","year":"2016","journal-title":"Phys. Chem. Chem. Phys."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1021\/jp013702z","article-title":"Red- versus blue-shifting hydrogen bonds: Are there fundamental distinctions?","volume":"106","author":"Scheiner","year":"2002","journal-title":"J. Phys. Chem. A"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1021\/acs.jctc.6b01133","article-title":"A Unified Theory for the Blue- and Red-Shifting Phenomena in Hydrogen and Halogen Bonds","volume":"13","author":"Wang","year":"2017","journal-title":"J. Chem. Theory Comput."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"12290","DOI":"10.1021\/ja010915t","article-title":"The nature of improper, blue-shifting hydrogen bonding verified experimentally","volume":"123","author":"Herrebout","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"8179","DOI":"10.1021\/acs.jpcb.7b06036","article-title":"C\u2013H\u00b7\u00b7\u00b7O Interaction in Methanol-Water Solution Revealed from Raman Spectroscopy and Theoretical Calculations","volume":"121","author":"Yu","year":"2017","journal-title":"J. Phys. Chem. B"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/18\/7\/2061\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T15:10:31Z","timestamp":1760195431000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/18\/7\/2061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,28]]},"references-count":71,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2018,7]]}},"alternative-id":["s18072061"],"URL":"https:\/\/doi.org\/10.3390\/s18072061","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2018,6,28]]}}}