{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T11:56:59Z","timestamp":1763035019359,"version":"build-2065373602"},"reference-count":33,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T00:00:00Z","timestamp":1534809600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["PD\/BD\/135023\/2017"],"award-info":[{"award-number":["PD\/BD\/135023\/2017"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"name":"North Portugal Regional Operational Program","award":["NanoSTIMA"],"award-info":[{"award-number":["NanoSTIMA"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Optical fiber tweezers have been gaining prominence in several applications in Biology and Medicine. Due to their outstanding focusing abilities, they are able to trap and manipulate microparticles, including cells, needing any physical contact and with a low degree of invasiveness to the trapped cell. Recently, we proposed a fiber tweezer configuration based on a polymeric micro-lens on the top of a single mode fiber, obtained by a self-guided photopolymerization process. This configuration is able to both trap and identify the target through the analysis of short-term portions of the back-scattered signal. In this paper, we propose a variant of this fabrication method, capable of producing more robust fiber tips, which produce stronger trapping effects on targets by as much as two to ten fold. These novel lenses maintain the capability of distinguish the different classes of trapped particles based on the back-scattered signal. This novel fabrication method consists in the introduction of a multi mode fiber section on the tip of a single mode (SM) fiber. A detailed description of how relevant fabrication parameters such as the length of the multi mode section and the photopolymerization laser power can be tuned for different purposes (e.g., microparticles trapping only, simultaneous trapping and sensing) is also provided, based on both experimental and theoretical evidences.<\/jats:p>","DOI":"10.3390\/s18092746","type":"journal-article","created":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T11:12:42Z","timestamp":1534849962000},"page":"2746","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Fabrication of Multimode-Single Mode Polymer Fiber Tweezers for Single Cell Trapping and Identification with Improved Performance"],"prefix":"10.3390","volume":"18","author":[{"given":"Sandra M.","family":"Rodrigues","sequence":"first","affiliation":[{"name":"INESC TEC-INESC Technology and Science, 4200-465 Porto, Portugal"},{"name":"Physics and Astronomy Department, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0413-587X","authenticated-orcid":false,"given":"Joana S.","family":"Paiva","sequence":"additional","affiliation":[{"name":"INESC TEC-INESC Technology and Science, 4200-465 Porto, Portugal"},{"name":"Physics and Astronomy Department, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"},{"name":"Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4139-7679","authenticated-orcid":false,"given":"Rita S. R.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"4Dcell and Elvesys, 75011 Paris, France"}]},{"given":"Olivier","family":"Soppera","sequence":"additional","affiliation":[{"name":"Institute of Material Science of Mulhouse, 68057 Mulhouse, France"}]},{"given":"Jo\u00e3o P. S.","family":"Cunha","sequence":"additional","affiliation":[{"name":"INESC TEC-INESC Technology and Science, 4200-465 Porto, Portugal"},{"name":"Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1484-2068","authenticated-orcid":false,"given":"Pedro A. S.","family":"Jorge","sequence":"additional","affiliation":[{"name":"INESC TEC-INESC Technology and Science, 4200-465 Porto, Portugal"},{"name":"Physics and Astronomy Department, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal"}]}],"member":"1968","published-online":{"date-parts":[[2018,8,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1103\/PhysRevLett.24.156","article-title":"Acceleration and trapping of particles by radiation pressure","volume":"24","author":"Ashkin","year":"1970","journal-title":"Phys. Rev. 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