{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T19:03:42Z","timestamp":1770145422132,"version":"3.49.0"},"reference-count":45,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T00:00:00Z","timestamp":1554768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Seventh Framework Programme","award":["607510"],"award-info":[{"award-number":["607510"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Knee osteoarthritis is a major cause of pain and disability in the elderly population with many daily living activities being difficult to perform as a result of this disease. The present study aimed to estimate the knee adduction moment and tibiofemoral joint contact force during daily living activities using a musculoskeletal model with inertial motion capture derived kinematics in an elderly population. Eight elderly participants were instrumented with 17 inertial measurement units, as well as 53 opto-reflective markers affixed to anatomical landmarks. Participants performed stair ascent, stair descent, and sit-to-stand movements while both motion capture methods were synchronously recorded. A musculoskeletal model containing 39 degrees-of-freedom was used to estimate the knee adduction moment and tibiofemoral joint contact force. Strong to excellent Pearson correlation coefficients were found for the IMC-derived kinematics across the daily living tasks with root mean square errors (RMSE) between 3\u00b0 and 7\u00b0. Furthermore, moderate to strong Pearson correlation coefficients were found in the knee adduction moment and tibiofemoral joint contact forces with RMSE between 0.006\u20130.014 body weight \u00d7 body height and 0.4 to 1 body weights, respectively. These findings demonstrate that inertial motion capture may be used to estimate knee adduction moments and tibiofemoral contact forces with comparable accuracy to optical motion capture.<\/jats:p>","DOI":"10.3390\/s19071681","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T05:58:07Z","timestamp":1554789487000},"page":"1681","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["Estimation of the Knee Adduction Moment and Joint Contact Force during Daily Living Activities Using Inertial Motion Capture"],"prefix":"10.3390","volume":"19","author":[{"given":"Jason M.","family":"Konrath","sequence":"first","affiliation":[{"name":"Department of Technology, Xsens Technologies B.V., Enschede 7521 PR, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6474-9377","authenticated-orcid":false,"given":"Angelos","family":"Karatsidis","sequence":"additional","affiliation":[{"name":"Department of Technology, Xsens Technologies B.V., Enschede 7521 PR, The Netherlands"},{"name":"Department of Biomedical Signals and Systems, Technical Medical Centre, University of Twente, Enschede 7500 AE, The Netherlands"}]},{"given":"H. Martin","family":"Schepers","sequence":"additional","affiliation":[{"name":"Department of Technology, Xsens Technologies B.V., Enschede 7521 PR, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5514-2503","authenticated-orcid":false,"given":"Giovanni","family":"Bellusci","sequence":"additional","affiliation":[{"name":"Department of Technology, Xsens Technologies B.V., Enschede 7521 PR, The Netherlands"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0584-271X","authenticated-orcid":false,"given":"Mark","family":"de Zee","sequence":"additional","affiliation":[{"name":"Department of Health Science and Technology, Aalborg University, Aalborg 9220, Denmark"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8275-9472","authenticated-orcid":false,"given":"Michael S.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Materials and Production, Aalborg University, Aalborg 9220, Denmark"}]}],"member":"1968","published-online":{"date-parts":[[2019,4,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1136\/ard.56.11.641","article-title":"Sensorimotor Changes and Functional Performance in Patients with Knee Osteoarthritis","volume":"56","author":"Hurley","year":"1997","journal-title":"Ann. 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