{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:42:53Z","timestamp":1778550173321,"version":"3.51.4"},"reference-count":78,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A new cellulose nanocrystal\u2013reduced graphene oxide (CNC\u2013rGO) nanocomposite was successfully used for mediatorless electrochemical sensing of methyl paraben (MP). Fourier-transform infrared spectroscopy (FTIR) and field-emission scanning electron microscopy (FESEM) studies confirmed the formation of the CNC\u2013rGO nanocomposite. Cyclic voltammetry (CV) studies of the nanocomposite showed quasi-reversible redox behavior. Differential pulse voltammetry (DPV) was employed for the sensor optimization. Under optimized conditions, the sensor demonstrated a linear calibration curve in the range of 2 \u00d7 10\u22124\u20139 \u00d7 10\u22124 M with a limit of detection (LOD) of 1 \u00d7 10\u22124 M. The MP sensor showed good reproducibility with a relative standard deviation (RSD) of about 8.20%. The sensor also exhibited good stability and repeatability toward MP determinations. Analysis of MP in cream samples showed recovery percentages between 83% and 106%. Advantages of this sensor are the possibility for the determination of higher concentrations of MP when compared with most other reported sensors for MP. The CNC\u2013rGO nanocomposite-based sensor also depicted good reproducibility and reusability compared to the rGO-based sensor. Furthermore, the CNC\u2013rGO nanocomposite sensor showed good selectivity toward MP with little interference from easily oxidizable species such as ascorbic acid.<\/jats:p>","DOI":"10.3390\/s19122726","type":"journal-article","created":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T02:42:46Z","timestamp":1560912166000},"page":"2726","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["A New Sensor for Methyl Paraben Using an Electrode Made of a Cellulose Nanocrystal\u2013Reduced Graphene Oxide Nanocomposite"],"prefix":"10.3390","volume":"19","author":[{"given":"Wan Elina Faradilla","family":"Wan Khalid","sequence":"first","affiliation":[{"name":"School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia"},{"name":"Faculty of Applied Sciences, Universiti Teknologi MARA Negeri Sembilan, Kuala Pilah Campus, Pekan Parit Tinggi, Kuala Pilah 72000, Negeri Sembilan, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad Nasir","family":"Mat Arip","sequence":"additional","affiliation":[{"name":"Forest Products Division, Forest Research Institute Malaysia, Selangor 52109, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latifah","family":"Jasmani","sequence":"additional","affiliation":[{"name":"Forest Products Division, Forest Research Institute Malaysia, Selangor 52109, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yook Heng","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.chroma.2014.10.063","article-title":"Simplified matrix solid phase dispersion procedure for the determination of parabens and benzophenone-ultraviolet filters in human placental tissue samples","volume":"1371","author":"Ballesteros","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.jchromb.2015.07.020","article-title":"Application of microwave-assisted micro-solid-phase extraction for determination of parabens in human ovarian cancer tissues","volume":"1000","author":"Sajid","year":"2015","journal-title":"J. Chromatogr. B"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/jat.958","article-title":"Concentrations of parabens in human breast tumours","volume":"24","author":"Darbre","year":"2004","journal-title":"J. Appl. Toxicol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.talanta.2015.04.055","article-title":"Parabens determination in cosmetic and personal care products exploiting a multi-syringe chromatographic (MSC) system and chemiluminescent detection","volume":"143","author":"Rodas","year":"2015","journal-title":"Talanta"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.talanta.2010.02.035","article-title":"Use of a capillary tube for collecting an extraction solvent lighter than water after dispersive liquid-liquid microextraction and its application in the determination of parabens in different samples by gas chromatography-Flame ionization detection","volume":"81","author":"Farajzadeh","year":"2010","journal-title":"Talanta"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.aca.2008.05.068","article-title":"Automated on-line column-switching HPLC-MS\/MS method with peak focusing for measuring parabens, triclosan, and other environmental phenols in human milk","volume":"622","author":"Ye","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"7333","DOI":"10.1007\/s00216-015-8895-8","article-title":"Fast and sensitive method to determine parabens by capillary electrophoresis using automatic reverse electrode polarity stacking mode: Application to hair samples","volume":"407","author":"Sako","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.msec.2013.11.021","article-title":"Development of a selective and sensitive voltammetric sensor for propylparaben based on a nanosized molecularly imprinted polymer-carbon paste electrode","volume":"36","author":"Gholivand","year":"2014","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.aca.2010.05.039","article-title":"Electrochemical sensor for parabens based on molecular imprinting polymers with dual-templates","volume":"673","author":"Wang","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"5690","DOI":"10.1039\/C6AY01489E","article-title":"An electrochemical sensor based on fullerene nanorods for the detection of paraben, an endocrine disruptor","volume":"8","author":"Rather","year":"2016","journal-title":"Anal. Methods"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.snb.2015.06.026","article-title":"Swift electrochemical detection of paraben an endocrine disruptor by In2O3 nanobricks","volume":"221","author":"Qurashi","year":"2015","journal-title":"Sens. Actuators B Chem."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.msec.2016.06.061","article-title":"Nanomolar detection of methylparaben by a cost-effective hemoglobin-based biosensor","volume":"69","author":"Hajian","year":"2016","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.talanta.2015.05.044","article-title":"Graphene\/polyvinylpyrrolidone\/polyaniline nanocomposite-modified electrode for simultaneous determination of parabens by high performance liquid chromatography","volume":"148","author":"Kajornkavinkul","year":"2016","journal-title":"Talanta"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jelechem.2018.02.025","article-title":"Reduced graphene oxide\/gold nanoparticles nanocomposite-modified glassy carbon electrode for determination of endocrine disruptor methylparaben","volume":"813","author":"Piovesan","year":"2018","journal-title":"J. Electroanal. Chem."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/DER.0000000000000147","article-title":"\u201cParabenoia\u201d debunked, or \u201cWho\u2019s afraid of parabens?\u201d","volume":"26","author":"Sasseville","year":"2015","journal-title":"Dermatitis"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1002\/smll.201402109","article-title":"Supporting\u2014Transparent and Flexible Cellulose Nanocrystal\/Reduced Graphene Oxide Film for Proximity Sensing","volume":"11","author":"Sadasivuni","year":"2014","journal-title":"Small"},{"key":"ref_17","unstructured":"Kafy, A., Akther, A., Shishir, M.I.R., Kim, H.C., Yun, Y., and Kim, J. (2016). Cellulose nanocrystalgraphene oxide composite film as humidity sensor. Sens. Actuators A Phys."},{"key":"ref_18","first-page":"1","article-title":"Novel synthesis of ZnO\/PMMA nanocomposites for photocatalytic applications","volume":"7","author":"Cantarella","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1126\/sciadv.aat7392","article-title":"Programmable wettability on photocontrolled graphene film","volume":"4","author":"Wang","year":"2018","journal-title":"Sci. Adv."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.carbpol.2017.01.036","article-title":"Hydrophobic kenaf nanocrystalline cellulose for the binding of curcumin","volume":"163","author":"Zainuddin","year":"2017","journal-title":"Carbohydr. Polym."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.carbpol.2012.02.066","article-title":"Synthesis and characterization of cationically modified nanocrystalline cellulose","volume":"89","author":"Zaman","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jcis.2015.03.002","article-title":"Synthesis and characterization of pH-responsive and fluorescent poly (amidoamine) dendrimer-grafted cellulose nanocrystals","volume":"450","author":"Chen","year":"2015","journal-title":"J. Colloid Interface Sci."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1088\/0957-4484\/22\/5\/055705","article-title":"Temperature dependence of graphene oxide reduced by hydrazine hydrate","volume":"22","author":"Ren","year":"2011","journal-title":"Nanotechnology"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.bios.2015.11.035","article-title":"Reduced graphene oxide-Hemin-Au nanohybrids: Facile one-pot synthesis and enhanced electrocatalytic activity towards the reduction of hydrogen peroxide","volume":"78","author":"Gu","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.talanta.2013.01.012","article-title":"Electrochemical sensor for bisphenol A based on magnetic nanoparticles decorated reduced graphene oxide","volume":"107","author":"Zhang","year":"2013","journal-title":"Talanta"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.jes.2017.08.022","article-title":"Adsorption of VOCs on reduced graphene oxide","volume":"67","author":"Yu","year":"2018","journal-title":"J. Environ. Sci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1007\/s10570-018-1723-5","article-title":"Advances in cellulose nanomaterials","volume":"25","author":"Kargarzadeh","year":"2018","journal-title":"Cellulose"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.snb.2014.11.072","article-title":"Electrodeposition of copper oxide\/polypyrrole\/reduced graphene oxide as a nonenzymatic glucose biosensor","volume":"209","author":"Nia","year":"2015","journal-title":"Sens. Actuators B Chem."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jelechem.2016.12.009","article-title":"Electrochemical sensing of nicotine using screen-printed carbon electrodes modified with nitrogen-doped graphene sheets","volume":"784","author":"Li","year":"2017","journal-title":"J. Electroanal. Chem."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bios.2014.06.043","article-title":"NADH dehydrogenase-like behavior of nitrogen-doped graphene and its application in NAD+-dependent dehydrogenase biosensing","volume":"62","author":"Gai","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.carbpol.2015.10.072","article-title":"Synergistic effect of cellulose nanocrystals\/graphene oxide nanosheets as functional hybrid nanofiller for enhancing properties of PVA nanocomposites","volume":"137","author":"Fihri","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1002\/polb.23490","article-title":"Cellulose nanocrystals and related nanocomposites: Review of some properties and challenges","volume":"52","author":"Mariano","year":"2014","journal-title":"J. Polym. Sci. Part B Polym. Phys."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.bios.2014.03.028","article-title":"Caffeine electrochemical sensor using imprinted film as recognition element based on polypyrrole, sol-gel, and gold nanoparticles hybrid nanocomposite modified pencil graphite electrode","volume":"60","author":"Rezaei","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"6436","DOI":"10.1039\/C5RA23935D","article-title":"Poly(diallyldimethylammonium chloride)\u2013cellulose nanocrystals supported Au nanoparticles for nonenzymatic glucose sensing","volume":"6","author":"Dong","year":"2016","journal-title":"RSC Adv."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bios.2015.04.007","article-title":"Multiplexed enzyme-free electrochemical immunosensor based on ZnO nanorods modified reduced graphene oxide-paper electrode and silver deposition-induced signal amplification strategy","volume":"71","author":"Sun","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.bios.2013.08.020","article-title":"Glad assisted synthesis of NiO nanorods for realization of enzymatic reagentless urea biosensor","volume":"52","author":"Tyagi","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.bios.2015.03.012","article-title":"A novel amperometric biosensor based on gold nanoparticles anchored on reduced graphene oxide for sensitive detection of L-lactate tumor biomarker","volume":"69","author":"Azzouzi","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.jelechem.2015.10.001","article-title":"Development and application of an electrochemical sensor modified with multi-walled carbon nanotubes and graphene oxide for the sensitive and selective detection of tetracycline","volume":"757","author":"Wong","year":"2015","journal-title":"J. Electroanal. Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.microc.2015.05.001","article-title":"Modified multiwalled carbon nanotube\/epoxy amperometric nanocomposite sensors with CuO nanoparticles for electrocatalytic detection of free chlorine","volume":"122","author":"Baeza","year":"2015","journal-title":"Microchem. J."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bios.2016.10.091","article-title":"Fully integrated ready-to-use paper-based electrochemical biosensor to detect nerve agents","volume":"93","author":"Cinti","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jelechem.2016.03.016","article-title":"Electrochemical degradation of butyl paraben on platinum and glassy carbon electrodes","volume":"769","author":"Gomes","year":"2016","journal-title":"J. Electroanal. Chem."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.snb.2012.12.015","article-title":"Characterization of an ultrasensitive biosensor based on a nano-Au\/DNA\/nano-Au\/poly(SFR) composite and its application in the simultaneous determination of dopamine, uric acid, guanine, and adenine","volume":"178","author":"Niu","year":"2013","journal-title":"Sens. Actuators B Chem."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.aca.2014.11.004","article-title":"Functional graphene-gold nano-composite fabricated electrochemical biosensor for direct and rapid detection of bisphenol A","volume":"853","author":"Pan","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/j.bios.2014.12.012","article-title":"Au nanoparticle\/graphene nanocomposite as a platform for the sensitive detection of NADH in human urine","volume":"66","author":"Govindhan","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jelechem.2016.12.001","article-title":"Ultra-sensitive phenol sensor based on overcoming surface fouling of reduced graphene oxide-zinc oxide composite electrode","volume":"785","author":"Sha","year":"2017","journal-title":"J. Electroanal. Chem."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.1016\/S1452-3981(23)19509-5","article-title":"Electrochemical behavior and voltammetric determination of sulfaguanidine at a glassy carbon electrode modified with a multi-walled carbon nanotube","volume":"7","author":"Fotouhi","year":"2012","journal-title":"Int. J. Electrochem. Sci."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jelechem.2014.02.006","article-title":"Nonenzymatic nitrite sensor based on a titanium dioxide nanoparticles\/ionic liquid composite electrode","volume":"719","author":"Li","year":"2014","journal-title":"J. Electroanal. Chem."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.foodchem.2015.04.009","article-title":"An electrochemical fungicide pyrimethanil sensor based on carbon nanotubes\/ionic-liquid construction modified electrode","volume":"187","author":"Yang","year":"2015","journal-title":"Food Chem."},{"key":"ref_49","unstructured":"Ghanbari, K., and Hajian, A. (2017). Electrochemical characterization of Au\/ZnO\/PPy\/RGO nanocomposite and its application for simultaneous determination of ascorbic acid (AA), epinephrine (EP) and uric acid (UA). J. Electroanal. Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3036","DOI":"10.1149\/2.0031705jes","article-title":"Electrochemical sensor based upon ruthenium doped TiO2 nanoparticles for the determination of flufenamic acid","volume":"164","author":"Shetti","year":"2017","journal-title":"J. Electrochem. Soc."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.snb.2015.01.056","article-title":"A new strategy for enhancing electrochemical sensing from MWCNTs modified electrode with Langmuir-Blodgett film and used in determination of methylparaben","volume":"211","author":"Wang","year":"2015","journal-title":"Sens. Actuators B Chem."},{"key":"ref_52","doi-asserted-by":"crossref","unstructured":"Muhammad, A., Yusof, N.A., Hajian, R., and Abdullah, J. (2016). Construction of an electrochemical sensor based on carbon nanotubes\/gold nanoparticles for trace determination of amoxicillin in bovine milk. Sensors, 16.","DOI":"10.3390\/s16010056"},{"key":"ref_53","doi-asserted-by":"crossref","unstructured":"Feier, B., Blidar, A., Pusta, A., Carciuc, P., and Cristea, C. (2019). Electrochemical sensor based on molecularly imprinted polymer for the detection of Cefalexin. Biosensors, 9.","DOI":"10.3390\/bios9010031"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep35419","article-title":"Selective detection of dopamine with an all PEDOT:PSS organic electrochemical transistor","volume":"6","author":"Gualandi","year":"2016","journal-title":"Sci. Rep."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.microc.2016.03.016","article-title":"Electrocatalytic oxidation of glucose onto carbon paste electrode modified with nickel hydroxide decorated NaA nanozeolite","volume":"128","author":"Rahimnejad","year":"2016","journal-title":"Microchem. J."},{"key":"ref_56","doi-asserted-by":"crossref","unstructured":"Tang, J., Song, Y., Berry, R.M., and Tam, K.C. (2014). Polyrhodanine coated cellulose nanocrystals as optical pH indicators. RSC Adv., 60249\u201360252.","DOI":"10.1039\/C4RA09043H"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.compositesb.2015.04.031","article-title":"Multifunctional graphene nanoplatelets\/cellulose nanocrystals composite paper","volume":"79","author":"Wang","year":"2015","journal-title":"Compos. Part B"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.snb.2013.09.040","article-title":"A regenerable screen-printed DNA biosensor based on acrylic microsphere-gold nanoparticle composite for genetically modified soybean determination","volume":"190","author":"Ulianas","year":"2014","journal-title":"Sens. Actuators B Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.snb.2015.03.003","article-title":"A novel method based on electrochemical approaches and multivariate calibrations for study and determination of methylparaben in the presence of unexpected interference in cosmetics","volume":"214","author":"Behpour","year":"2015","journal-title":"Sens. Actuators B Chem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s11743-014-1574-5","article-title":"Extraction of parabens from water samples using cloud point extraction with a non-ionic surfactant with \u03b2-cyclodextrin as modifier","volume":"17","author":"Noorashikin","year":"2014","journal-title":"J. Surfactants Deterg."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1039\/C3AY41413B","article-title":"Extraction and determination of parabens in water samples using an aqueous two-phase system of ionic liquid and salts with beta-cyclodextrin as the modifier coupled with high performance liquid chromatography","volume":"6","author":"Noorashikin","year":"2014","journal-title":"Anal. Methods"},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.electacta.2012.07.032","article-title":"Electrochemical detection of triclosan at a glassy carbon electrode modifies with carbon nanodots and chitosan","volume":"80","author":"Dai","year":"2012","journal-title":"Electrochim. Acta"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.snb.2015.12.032","article-title":"An enzyme-free electrochemical sensor based on reduced graphene oxide\/Co3O4 nanospindle composite for sensitive detection of nitrite","volume":"227","author":"Haldorai","year":"2016","journal-title":"Sens. Actuators B Chem."},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.bios.2013.08.018","article-title":"Novel paper-based cholesterol biosensor using graphene\/polyvinylpyrrolidone\/polyaniline nanocomposite","volume":"52","author":"Ruecha","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"6690","DOI":"10.1021\/acsami.5b00053","article-title":"Influence of the surface structure of graphene oxide on the adsorption of aromatic organic compounds from water","volume":"7","author":"Yan","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.snb.2014.09.026","article-title":"Fabrication of highly sensitive uric acid biosensor based on directly grown ZnO nanosheets on electrode surface","volume":"206","author":"Ahmad","year":"2015","journal-title":"Sens. Actuators B Chem."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1080\/00032719.2012.682238","article-title":"Determination of 19 preservatives in various matrices by high-performance liquid chromatography","volume":"45","author":"Cha","year":"2012","journal-title":"Anal. Lett."},{"key":"ref_68","doi-asserted-by":"crossref","unstructured":"Marengo, E., Gennaro, M.C., and Gianotti, V. (2001). A simplex-optimized chromatographic separation of fourteen cosmetic preservatives: Analysis of commercial products. J. Chromatogr. Sci., 339\u2013344.","DOI":"10.1093\/chromsci\/39.8.339"},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.talanta.2003.07.005","article-title":"Voltammetric determination of salicylic acid in pharmaceuticals formulations of acetylsalicylic acid","volume":"62","author":"Torriero","year":"2004","journal-title":"Talanta"},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.sna.2014.03.033","article-title":"Electroanalytical method for the determination of methylparaben","volume":"212","author":"Naik","year":"2014","journal-title":"Sens. Actuators A Phys."},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1080\/02786820152546798","article-title":"Hygroscopic study of glucose, citric acid, and sorbitol using an electrodynamic balance: Comparison with UNIFAC predictions","volume":"35","author":"Peng","year":"2001","journal-title":"Aerosol Sci. Technol."},{"key":"ref_72","doi-asserted-by":"crossref","unstructured":"He, B.S., and Zhang, J.X. (2017). Rapid detection of ascorbic acid based on a dual-electrode sensor system using a powder microelectrode embedded with carboxyl multi-walled carbon nanotubes. Sensors, 17.","DOI":"10.3390\/s17071549"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.snb.2016.08.029","article-title":"Voltammetric determination of methylparaben and its DNA interaction using a novel platform based on carbon nanofibers and cobalt-nickel-palladium nanoparticles","volume":"239","author":"Baytak","year":"2017","journal-title":"Sens. Actuators B Chem."},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.snb.2017.05.083","article-title":"Methylparaben quantification via electrochemical sensor based on reduced graphene oxide decorated with ruthenium nanoparticles","volume":"251","author":"Prado","year":"2017","journal-title":"Sens. Actuators B Chem."},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.msec.2016.11.080","article-title":"A novel electrochemical platform based on carbon nanofibers and tri-metallic nanoparticles of gold, nickel and cobalt for the quantification of ethyl paraben","volume":"72","author":"Baytak","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_76","unstructured":"Indrasti, D., Lioe, H.N., and Adawiyah, D.R. (2013, January 9\u201311). Evaluation of methyl paraben content in sweet soy-sauce in commercial instant fried noodle. Proceedings of the 13th ASEAN Food Conference, Singapore."},{"key":"ref_77","first-page":"199","article-title":"HPLC method for simultaneous determination of ketoprofen and preservatives in gel formulation","volume":"6","author":"Tsvetkova","year":"2014","journal-title":"Int. J. Pharm. Pharm. Sci."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/S0278-6915(02)00107-2","article-title":"Evaluation of the health aspects of methyl paraben: A review of the published literature","volume":"40","author":"Soni","year":"2002","journal-title":"Food Chem. Toxicol."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/12\/2726\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T12:59:11Z","timestamp":1760187551000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/12\/2726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,18]]},"references-count":78,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,6]]}},"alternative-id":["s19122726"],"URL":"https:\/\/doi.org\/10.3390\/s19122726","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,18]]}}}