{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:11:08Z","timestamp":1769843468209,"version":"3.49.0"},"reference-count":55,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T00:00:00Z","timestamp":1572480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","award":["CB-2015-251201"],"award-info":[{"award-number":["CB-2015-251201"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Secretar\u00eda de Energ\u00eda","award":["SENER-2013-04-211704"],"award-info":[{"award-number":["SENER-2013-04-211704"]}]},{"DOI":"10.13039\/501100007161","name":"Secretar\u00eda de Investigaci\u00f3n y Posgrado, Instituto Polit\u00e9cnico Nacional","doi-asserted-by":"publisher","award":["SIP-2019"],"award-info":[{"award-number":["SIP-2019"]}],"id":[{"id":"10.13039\/501100007161","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007177","name":"Comisi\u00f3n de Operaci\u00f3n y Fomento de Actividades Acad\u00e9micas, Instituto Polit\u00e9cnico Nacional","doi-asserted-by":"publisher","award":["2019"],"award-info":[{"award-number":["2019"]}],"id":[{"id":"10.13039\/501100007177","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The evolution of the optical absorptive effects exhibited by plasmonic nanoparticles was systematically analyzed by electronic signals modulated by a R\u00f6ssler attractor system. A sol-gel approach was employed for the preparation of the studied Au nanoparticles embedded in a TiO2 thin solid film. The inclusion of the nanoparticles in an inhomogeneous biological sample integrated by human cells deposited in an ITO glass substrate was evaluated with a high level of sensitivity using an opto-electronic chaotic circuit. The optical response of the nanoparticles was determined using nanosecond laser pulses in order to guarantee the sensing performance of the system. It was shown that high-intensity irradiances at a wavelength of 532 nm could promote a change in the absorption band of the localized surface plasmon resonance associated with an increase in the nanoparticle density of the film. Moreover, it was revealed that interferometrically-controlled energy transfer mechanisms can be useful for thermo-plasmonic functions and sharp selective optical damage induced by the vectorial nature of light. Immediate applications of two-wave mixing techniques, together with chaotic effects, can be contemplated in the development of nanostructured sensors and laser-induced controlled explosions, with potential applications for biomedical photo-thermal processes.<\/jats:p>","DOI":"10.3390\/s19214728","type":"journal-article","created":{"date-parts":[[2019,10,31]],"date-time":"2019-10-31T06:33:29Z","timestamp":1572503609000},"page":"4728","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Chaotic Signatures Exhibited by Plasmonic Effects in Au Nanoparticles with Cells"],"prefix":"10.3390","volume":"19","author":[{"given":"Hilario","family":"Martines-Arano","sequence":"first","affiliation":[{"name":"Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07738, Mexico"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6610-5559","authenticated-orcid":false,"given":"Blanca Estela","family":"Garc\u00eda-P\u00e9rez","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda, Escuela Nacional de Ciencias Biol\u00f3gicas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 11340, Mexico"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5021-4192","authenticated-orcid":false,"given":"M\u00f3nica Araceli","family":"Vidales-Hurtado","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Ciencia Aplicada y Tecnolog\u00eda Avanzada Unidad Quer\u00e9taro, Instituto Polit\u00e9cnico Nacional, Santiago de Quer\u00e9taro, Quer\u00e9taro 76090, Mexico"}]},{"given":"Mart\u00edn","family":"Trejo-Valdez","sequence":"additional","affiliation":[{"name":"Escuela Superior de Ingenier\u00eda Qu\u00edmica e Industrias Extractivas, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07738, Mexico"}]},{"given":"Luis H\u00e9ctor","family":"Hern\u00e1ndez-G\u00f3mez","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07738, Mexico"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9255-2416","authenticated-orcid":false,"given":"Carlos","family":"Torres-Torres","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Estudios de Posgrado e Investigaci\u00f3n, Escuela Superior de Ingenier\u00eda Mec\u00e1nica y El\u00e9ctrica Unidad Zacatenco, Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico 07738, Mexico"}]}],"member":"1968","published-online":{"date-parts":[[2019,10,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"315101","DOI":"10.1088\/1751-8113\/49\/31\/315101","article-title":"Templates and subtemplates of R\u00f6ssler attractors from a bifurcation diagram","volume":"49","author":"Rosalie","year":"2016","journal-title":"J. Phys. A Math. Theor."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1450045","DOI":"10.1142\/S021812741450045X","article-title":"Toward a general procedure for extracting templates from chaotic attractors bounded by high genus torus","volume":"24","author":"Rosalie","year":"2014","journal-title":"Int. J. Bifurc. Chaos"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1109\/TPAMI.2016.2533388","article-title":"Shape distributions of nonlinear dynamical systems for video-based inference","volume":"38","author":"Vinay","year":"2016","journal-title":"IEEE Trans. Pattern Anal. Mach. Intell."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1109\/TCSI.2015.2415172","article-title":"Synchronization in on-off stochastic networks: Windows of opportunity","volume":"62","author":"Jeter","year":"2015","journal-title":"IEEE Trans. Circuits Syst."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s11071-011-0006-6","article-title":"A new image encryption method: Parallel sub-image encryption with hyper chaos","volume":"67","author":"Mirzaei","year":"2012","journal-title":"Nonlinear Dynam."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"6079","DOI":"10.1109\/TIP.2018.2864918","article-title":"Chaotic Sensing","volume":"27","author":"Shekhar","year":"2018","journal-title":"IEEE Trans. Image Process."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3788","DOI":"10.1177\/0142331217731617","article-title":"Finite-time chaos synchronization and its application in wireless sensor networks","volume":"40","author":"Behrouz","year":"2018","journal-title":"Trans. Inst. Meas. Control."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"5588","DOI":"10.1039\/C6CS00738D","article-title":"Materials learning from life: Concepts for active, adaptive and autonomous molecular systems. Chem","volume":"46","author":"Andreas","year":"2017","journal-title":"Soc. Rev."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.neunet.2015.09.012","article-title":"Finite-time synchronization of fractional-order memristor-based neural networks with time delays","volume":"73","author":"Velmurugan","year":"2016","journal-title":"Neural Netw."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.physd.2009.03.010","article-title":"Bounds for the chaotic region in the Lorenz model","volume":"238","author":"Barrio","year":"2009","journal-title":"Physica D"},{"key":"ref_11","unstructured":"Botha, A.E., and Dednam, W. (2014, January 7\u201311). Computer assisted \u2018proof\u2019 of the global existence of periodic orbits in the R\u00f6ssler system. Proceedings of the 59th Annual Conference of the SAIP, Johannesburg, South Africa."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"8772","DOI":"10.1038\/s41598-017-08585-8","article-title":"Ultrafast photonic reinforcement learning based on laser chaos","volume":"7","author":"Makoto","year":"2017","journal-title":"Sci. Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"11433","DOI":"10.1007\/s11042-015-2861-5","article-title":"A novel block chaotic encryption scheme for remote sensing image","volume":"75","author":"Ye","year":"2016","journal-title":"Multimed. Tools Appl."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11042-012-1331-6","article-title":"An image encryption algorithm based on hyper-chaos and DNA sequence","volume":"72","author":"Huang","year":"2014","journal-title":"Multimed. Tools Appl."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"191109","DOI":"10.1063\/1.4948761","article-title":"A multi-GHz chaotic optoelectronic oscillator based on laser terminal voltage","volume":"108","author":"Chang","year":"2016","journal-title":"Appl. Phys. Lett."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.optlastec.2014.01.015","article-title":"Cryptanalyzing a RGB image encryption algorithm based on DNA encoding and chaos map","volume":"60","author":"Liu","year":"2014","journal-title":"Opt. Laser Technol."},{"key":"ref_17","first-page":"2865195","article-title":"Analyzing Chaos Systems and Fine Spectrum Sensing Using Detrended Fluctuation Analysis Algorithm","volume":"2016","author":"Shbat","year":"2016","journal-title":"Math. Probl. Eng."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"33130","DOI":"10.1364\/OE.23.033130","article-title":"Tbits\/s physical random bit generation based on mutually coupled semiconductor laser chaotic entropy source","volume":"23","author":"Xi","year":"2015","journal-title":"Opt. Express"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1364\/OPTICA.5.000756","article-title":"Reinforcement learning in a large-scale photonic recurrent neural network","volume":"5","author":"Bueno","year":"2018","journal-title":"Optica"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"121006","DOI":"10.1115\/1.4041179","article-title":"Uncertainty Propagation Analysis of Computational Models in Laser Powder Bed Fusion Additive Manufacturing Using Polynomial Chaos Expansions","volume":"140","author":"Gustavo","year":"2018","journal-title":"J. Manuf. Sci. Eng."},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Dumeige, Y., and Raineri, F. (2006). Nonlinear optics in nano-and microstructures. Nanophotonics, ISTE Ltd.","DOI":"10.1002\/9780470612460.ch5"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1126\/science.1114849","article-title":"Plasmonics: Merging photonics and electronics at nanoscale dimensions","volume":"311","author":"Ozba","year":"2006","journal-title":"Science"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"075123","DOI":"10.1103\/PhysRevB.95.075123","article-title":"Interaction effects in a chaotic graphene quantum billiard","volume":"95","year":"2017","journal-title":"Phys. Rev. B"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1007\/s11538-017-0310-5","article-title":"Sensitivity of Chaos Measures in Detecting Stress in the Focusing Control Mechanism of the Short-Sighted Eye","volume":"79","author":"Hampson","year":"2017","journal-title":"Bull. Math. Biol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"295701","DOI":"10.1088\/0957-4484\/26\/29\/295701","article-title":"Collective optical Kerr effect exhibited by an integrated configuration of silicon quantum dots and gold nanoparticles embedded in ion-implanted silica","volume":"26","author":"Oliver","year":"2015","journal-title":"Nanotechnology"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.snb.2018.07.165","article-title":"Gold nanoparticle-embedded DNA thin films for ultraviolet photodetectors","volume":"275","author":"Mitta","year":"2018","journal-title":"Sens. Actuators B Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molliq.2019.02.073","article-title":"Dynamic and plasmonic response exhibited by Au nanoparticles suspended in blood plasma and cerebrospinal fluids","volume":"281","year":"2019","journal-title":"J. Mol. Liq."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/s41524-019-0184-1","article-title":"Plasmon-enhanced light\u2013matter interactions and applications","volume":"5","author":"Huakang","year":"2019","journal-title":"npj Comput. Mater."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1021\/cr2001178","article-title":"Gold nanoparticles in chemical and biological sensing","volume":"112","author":"Saha","year":"2012","journal-title":"Chem. Rev."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.solener.2013.09.026","article-title":"Plasmonic effect of gold nanoparticles in organic solar cells","volume":"106","author":"Notariannia","year":"2014","journal-title":"Sol. Energy"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S1748-0132(07)70116-0","article-title":"Using gold nanoparticles for catalysis","volume":"2","author":"Thompson","year":"2007","journal-title":"Nano Today"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.3390\/nano1010031","article-title":"Functionalized gold nanoparticles and their biomedical applications","volume":"1","author":"Tiwari","year":"2011","journal-title":"Nanomaterials"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"10108","DOI":"10.1021\/jp101050p","article-title":"Contribution of the two-photon absorption to the third order nonlinearity of Au nanoparticles embedded in TiO2 films and in ethanol suspension","volume":"114","year":"2010","journal-title":"J. Phys. Chem. C"},{"key":"ref_34","unstructured":"Bell, J.G. (2017). Nonlinear Instabilities in Chemical and Electrochemical Systems. [Ph.D. Thesis, University of Windsor]."},{"key":"ref_35","first-page":"11","article-title":"Halimatussadiyah. Design and Analysis Bidirectional Chaotic Synchronization of Rossler Circuit and Its Application for Secure Communication","volume":"1","author":"Sambas","year":"2013","journal-title":"Appl. Math. Sci."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"012099","DOI":"10.1088\/1742-6596\/1003\/1\/012099","article-title":"Chaotic behaviour of the Rossler model and its analysis by using bifurcations of limit cycles and chaotic attractors","volume":"1003","author":"Ibrahim","year":"2018","journal-title":"J. Phys. Conf. Ser."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1016\/j.optcom.2008.02.037","article-title":"Measurements of nonlinear optical refraction and absorption in an amino-triazole push-pull derivative by a vectorial self-diffraction method","volume":"281","author":"Khomenko","year":"2008","journal-title":"Opt. Commun."},{"key":"ref_38","unstructured":"Hecht, E. (2002). Optics, Addison Wesley. [4th ed.]."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"5278","DOI":"10.1016\/j.apsusc.2010.10.146","article-title":"Characterization of Ag and Au nanoparticles created by nanosecond pulsed laser ablation in double distilled water","volume":"257","author":"Nikolov","year":"2011","journal-title":"Appl. Surf. Sci."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"1600327","DOI":"10.1002\/advs.201600327","article-title":"Laser-Triggered Small Interfering RNA Releasing Gold Nanoshells against Heat Shock Protein for Sensitized Photothermal Therapy","volume":"4","author":"Zhaohui","year":"2017","journal-title":"Adv. Sci."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.expthermflusci.2016.01.004","article-title":"Electrical Conductivity, Viscosity, and Density of Different Nanofluids: An Experimental Study","volume":"74","author":"Sina","year":"2016","journal-title":"Exp. Therm. Fluid Sci."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"5699","DOI":"10.1038\/s41598-019-42174-1","article-title":"Superlinear photoluminescence by ultrafast laser pulses in dielectric matrices with metal nanoclusters","volume":"9","author":"Bornacelli","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"4228","DOI":"10.1039\/C7NR07304F","article-title":"Plasmonic nanoparticles embedded in single crystals synthesized by gold ion implantation for enhanced optical nonlinearity and efficient Q-switched lasing","volume":"10","author":"Nie","year":"2018","journal-title":"Nanoscale"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.jnoncrysol.2017.12.036","article-title":"Linear and nonlinear optical properties of gold nanoparticles doped borate glasses","volume":"482","author":"Jagannath","year":"2018","journal-title":"J. Non-Cryst. Solids"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Zhang, Y., Huang, T., Jorgens, D.M., Nickerson, A., Lin, L.-J., and Pelz, J. (2017). Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative superresolution microscopy. PLoS ONE, 12.","DOI":"10.1371\/journal.pone.0176839"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1021\/nl070345g","article-title":"Immuno Gold Nanocages with Tailored Optical Properties for Targeted Photothermal Destruction of Cancer Cells","volume":"7","author":"Chen","year":"2007","journal-title":"Nano Lett."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"G\u00f3mez, F.R., Rubira, R.J.G., Camacho, S.A., Martin, C.S., da Silva, R.R., Constantino, C.J.L., Alessio, P., Oliveira, O.N., and Mej\u00eda-Salazar, J.R. (2018). Surface Plasmon Resonances in Silver Nanostars. Sensors, 18.","DOI":"10.3390\/s18113821"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.envpol.2015.04.018","article-title":"Chloride-induced shape transformation of silver nanoparticles in a water environment","volume":"204","author":"Zhang","year":"2015","journal-title":"Environ. Pollut."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00901284","article-title":"Pulsed laser heating calculations incorporating vapourization","volume":"25","author":"Jain","year":"1981","journal-title":"Appl. Phys."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.optlastec.2015.06.027","article-title":"Structured strengthening by two-wave optical ablation in silica with gold nanoparticles","volume":"75","author":"Oliver","year":"2015","journal-title":"Opt. Laser Technol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/nphoton.2011.287","article-title":"A photon-driven micromotor can direct nerve fibre growth","volume":"6","author":"Wu","year":"2011","journal-title":"Nat. Photonics"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"015004","DOI":"10.1088\/2040-8986\/19\/1\/015004","article-title":"Instabilities in the optical response of a semiconductor quantum dot\u2014Metal nanoparticle heterodimer: Self-oscillations and chaos","volume":"19","author":"Bintoro","year":"2017","journal-title":"J. Opt."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"043819","DOI":"10.1103\/PhysRevA.91.043819","article-title":"Self-pulsing in Tm-doped YAlO3 lasers: Excited-state absorption and chaos","volume":"91","author":"Ka","year":"2015","journal-title":"Phys. Rev. A"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1364\/OE.25.002031","article-title":"Optical sensors using chaotic correlation fiber loop ring down","volume":"25","author":"Lingzhen","year":"2017","journal-title":"Opt. Express"},{"key":"ref_55","unstructured":"Lei, Z., Fengchun, T., and David, Z. (2018). Chaotic Time Series-Based Sensor Drift Prediction. Electronic Nose: Algorithmic Challenges, Springer."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/21\/4728\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:30:43Z","timestamp":1760189443000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/21\/4728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,31]]},"references-count":55,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2019,11]]}},"alternative-id":["s19214728"],"URL":"https:\/\/doi.org\/10.3390\/s19214728","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,31]]}}}