{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T23:02:51Z","timestamp":1785884571814,"version":"3.56.0"},"reference-count":29,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2019,11,9]],"date-time":"2019-11-09T00:00:00Z","timestamp":1573257600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In several application fields, plasmonic sensor platforms combined with bio-receptors are intensively used to obtain biosensors. Most of these commercial devices are based on a disposable chip. Usually a gold chip, functionalized with a specific bio-receptor, inside a costly sensor system, is used. In this work, we propose a low-cost and small-size sensor system, used for monitoring a disposable plasmonic chip, based on an innovative optical waveguide made of bacterial cellulose (BC). In particular, we have sputtered gold on the green slab waveguide that is able to excite localized surface plasmon resonance (LSPR). Experimental results are presented on the capabilities of using the BC-based composite as an eco-friendly plasmonic sensor platform, which could be exploited for realizing disposable biosensors. The sensor has been used with optical fibers and simple equipment. More specifically, the fibers connect the green disposable LSPR sensor with a light source and with a spectrometer. The novel plasmonic sensing approach has been tested using two different optical waveguide configurations of BC, with and without ions inside BC.<\/jats:p>","DOI":"10.3390\/s19224894","type":"journal-article","created":{"date-parts":[[2019,11,12]],"date-time":"2019-11-12T04:07:07Z","timestamp":1573531627000},"page":"4894","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["An Eco-Friendly Disposable Plasmonic Sensor Based on Bacterial Cellulose and Gold"],"prefix":"10.3390","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7769-0984","authenticated-orcid":false,"given":"Nunzio","family":"Cennamo","sequence":"first","affiliation":[{"name":"Department of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Trigona","sequence":"additional","affiliation":[{"name":"Department of Electrical, Electronics and Computer Engineering (DIEEI), University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Graziani","sequence":"additional","affiliation":[{"name":"Department of Electrical, Electronics and Computer Engineering (DIEEI), University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Zeni","sequence":"additional","affiliation":[{"name":"Department of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Arcadio","sequence":"additional","affiliation":[{"name":"Department of Engineering, University of Campania Luigi Vanvitelli, Via Roma 29, 81031 Aversa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Di Pasquale","sequence":"additional","affiliation":[{"name":"Dipartimento di Scienze Chimiche, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6814-9977","authenticated-orcid":false,"given":"Antonino","family":"Pollicino","sequence":"additional","affiliation":[{"name":"Department of Civil Engineering and Architecture, University of Catania, Viale Andrea Doria 6, 95125 Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,11,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1021\/acs.analchem.5b04298","article-title":"Fiber-Optic Chemical Sensors and Biosensors (2013\u20132015)","volume":"88","author":"Wang","year":"2016","journal-title":"Anal. Chem."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1109\/JSEN.2007.897946","article-title":"Fiber-optic sensors based on surface Plasmon resonance: A comprehensive review","volume":"7","author":"Anuj","year":"2007","journal-title":"IEEE Sens. J."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2009\/979761","article-title":"Surface plasmon resonance-based fiber optic sensors: Principle, probe designs, and some applications","volume":"2009","author":"Gupta","year":"2009","journal-title":"J. Sens."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1088\/0963-9659\/5\/2\/006","article-title":"Chemical sensing by surface plasmon resonance in a multimode optical fibre","volume":"5","author":"Trouillet","year":"1996","journal-title":"Pure Appl. Opt."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.snb.2007.03.010","article-title":"A review of fiber-optic biosensors","volume":"125","author":"Leung","year":"2007","journal-title":"Sens. Actuators B Chem."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11468-008-9055-1","article-title":"Sensitivity of optical fiber sensor based on surface plasmon resonance: Modeling and experiments","volume":"3","author":"Kanso","year":"2008","journal-title":"Plasmonics"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s11468-008-9057-z","article-title":"Influence of design parameters on the performance of a surface plasmon sensor based fiber optic sensor","volume":"3","author":"Dwivedi","year":"2008","journal-title":"Plasmonics"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.snb.2004.08.017","article-title":"Gold thickness dependence of SPR-based hetero-core structured optical fiber sensor","volume":"106","author":"Iga","year":"2005","journal-title":"Sens. Actuators B Chem."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.optcom.2004.10.013","article-title":"On the sensitivity and signal to noise ratio of a step-index fiber optic surface plasmon resonance sensor with bimetallic layers","volume":"245","author":"Sharma","year":"2005","journal-title":"Opt. Commun."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/2155-6210.1000194","article-title":"Polymer Fiber Optic Sensors-A Mini Review of their Synthesis and Applications","volume":"7","author":"Jin","year":"2016","journal-title":"J. Biosens. Bioelectron."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Cennamo, N., Zeni, L., Catalano, E., Arcadio, F., and Minardo, A. (2018). Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers. Appl. Sci., 8.","DOI":"10.3390\/app8071172"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Cennamo, N., Mattiello, F., and Zeni, L. (2017). Slab Waveguide and Optical Fibers for Novel Plasmonic Sensor Configurations. Sensors, 17.","DOI":"10.3390\/s17071488"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1109\/TIM.2018.2879170","article-title":"A novel sensing methodology to detect furfural in water, exploiting MIPs and InkJet-Printed optical waveguides","volume":"68","author":"Cennamo","year":"2019","journal-title":"IEEE Trans. Instrum. Meas."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"4822","DOI":"10.1109\/JSEN.2016.2549271","article-title":"SPR Sensor Platform Based on a Novel Metal Bilayer Applied on D-Shaped Plastic Optical Fibers for Refractive Index Measurements in the Range 1.38\u20131.42","volume":"16","author":"Cennamo","year":"2016","journal-title":"IEEE Sens. J."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Cennamo, N., Trigona, C., Graziani, S., Zeni, L., Arcadio, F., Di Pasquale, G., and Pollicino, A. (2019, January 9\u201311). A Green slab waveguide for plasmonic sensors based on Bacterial Cellulose. Proceedings of the 7th International Symposium on Sensor Science (I3S 2019), Naples, Italy.","DOI":"10.3390\/proceedings2019015036"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.bios.2015.06.041","article-title":"Green in-situ synthesized silver nanoparticles embedded in bacterial cellulose nanopaper as a bionanocomposite plasmonic sensor","volume":"74","author":"Pourreza","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.snb.2016.09.172","article-title":"Low cost, flexible and biodegradable touch sensor fabricated by solvent-free processing of graphite on cellulose paper","volume":"242","author":"Kanaparthi","year":"2017","journal-title":"Sens. Actuators B Chem."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"19048","DOI":"10.1021\/acsami.7b04927","article-title":"Engineering and Characterization of Bacterial Nanocellulose Films as Low Cost and Flexible Sensor Material","volume":"9","author":"Mangayil","year":"2017","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.snb.2010.02.046","article-title":"Bacterial Cellulose actuator with electrically driven bending deformation in hydrated condition","volume":"146","author":"Jeon","year":"2010","journal-title":"Sens. Actuators B Chem."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Di Pasquale, G., Graziani, S., Pollicino, A., and Trigona, C. (2019, January 20\u201323). \u201cPaper\u201d Based Sensor for Deformation Measurements. Proceedings of the IEEE I2MTC 2019, Auckland, New Zealand.","DOI":"10.1109\/I2MTC.2019.8826962"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Di Pasquale, G., Graziani, S., Pollicino, A., and Trigona, C. (2019, January 11\u201313). Green Inertial Sensors based on Bacterial Cellulose. Proceedings of the 2019 IEEE Sensors Applications Symposium (SAS), Sophia Antipolis, France.","DOI":"10.1109\/SAS.2019.8706112"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.optlastec.2018.06.028","article-title":"Slab plasmonic platforms combined with Plastic Optical Fibers and Molecularly Imprinted Polymers for chemical sensing","volume":"107","author":"Zeni","year":"2018","journal-title":"Opt. Laser Technol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"7663","DOI":"10.1109\/JSEN.2016.2603168","article-title":"Markers detection in transformer oil by plasmonic chemical sensor system based on POF and MIPs","volume":"16","author":"Cennamo","year":"2016","journal-title":"IEEE Sens. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s13320-017-0418-0","article-title":"A Study on Refractive Index Sensors Based on Optical Micro-Ring Resonators","volume":"7","author":"Tsigaridas","year":"2017","journal-title":"Photonic Sens."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1364\/OE.16.001020","article-title":"On the performance quantification of resonant refractive index sensors","volume":"16","author":"White","year":"2008","journal-title":"Opt. Express"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"12011","DOI":"10.1364\/OE.15.012011","article-title":"Refractometric sensor based on whispering-gallery modes of thin capillaries","volume":"15","author":"Zamora","year":"2007","journal-title":"Opt. Express"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.snb.2016.02.074","article-title":"Development of LSPR based U-bent plastic optical fiber sensors","volume":"230","author":"Gowri","year":"2016","journal-title":"Sens. Actuators B Chem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.optcom.2012.11.087","article-title":"Localized surface plasmon resonance based fiber optic sensor with nanoparticles","volume":"292","author":"Rani","year":"2013","journal-title":"Opt. Commun."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.snb.2013.09.094","article-title":"LSPR optical fibre sensors based on hollow gold nanostructures","volume":"191","author":"Tu","year":"2014","journal-title":"Sens. Actuators B Chem."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/22\/4894\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:33:14Z","timestamp":1760189594000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/19\/22\/4894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,9]]},"references-count":29,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2019,11]]}},"alternative-id":["s19224894"],"URL":"https:\/\/doi.org\/10.3390\/s19224894","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,9]]}}}