{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T16:06:15Z","timestamp":1760889975958,"version":"build-2065373602"},"reference-count":36,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2019,12,25]],"date-time":"2019-12-25T00:00:00Z","timestamp":1577232000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","award":["HDTRA13964"],"award-info":[{"award-number":["HDTRA13964"]}],"id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Vapor sensing via light reflected from photonic crystals has been increasingly studied as a means to rapidly identify analytes, though few studies have characterized vapor mixtures or chemical warfare agent simulants via this technique. In this work, light reflected from the natural photonic crystals found within the wing scales of the Morpho didius butterfly was analyzed after exposure to binary and tertiary mixtures containing dimethyl methylphosphonate, a nerve agent simulant, and dichloropentane, a mustard gas simulant. Distinguishable spectra were generated with concentrations tested as low as 30 ppm and 60 ppm for dimethyl methylphosphonate and dichloropentane, respectively. Individual vapors, as well as mixtures, yielded unique responses over a range of concentrations, though the response of binary and tertiary mixtures was not always found to be additive. Thus, while selective and sensitive to vapor mixtures containing chemical warfare agent simulants, this technique presents challenges to identifying these simulants at a sensitivity level appropriate for their toxicity.<\/jats:p>","DOI":"10.3390\/s20010157","type":"journal-article","created":{"date-parts":[[2019,12,25]],"date-time":"2019-12-25T11:07:48Z","timestamp":1577272068000},"page":"157","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Vapor Selectivity of a Natural Photonic Crystal to Binary and Tertiary Mixtures Containing Chemical Warfare Agent Simulants"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-2814","authenticated-orcid":false,"given":"Joshua","family":"Kittle","sequence":"first","affiliation":[{"name":"Department of Chemistry, United States Air Force Academy, 2355 Fairchild Drive, Colorado Springs, CO 80840, USA"}]},{"given":"Benjamin","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Chemistry, United States Air Force Academy, 2355 Fairchild Drive, Colorado Springs, CO 80840, USA"}]},{"given":"Courtney","family":"Kunselman","sequence":"additional","affiliation":[{"name":"Department of Chemistry, United States Air Force Academy, 2355 Fairchild Drive, Colorado Springs, CO 80840, USA"}]},{"given":"Aimee","family":"Morey","sequence":"additional","affiliation":[{"name":"Department of Chemistry, United States Air Force Academy, 2355 Fairchild Drive, Colorado Springs, CO 80840, USA"}]},{"given":"Andrea","family":"Abel","sequence":"additional","affiliation":[{"name":"Department of Chemistry, United States Air Force Academy, 2355 Fairchild Drive, Colorado Springs, CO 80840, USA"}]}],"member":"1968","published-online":{"date-parts":[[2019,12,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1006\/taap.2002.9449","article-title":"Biomonitoring of exposure to chemical warfare agents: A review","volume":"184","author":"Noort","year":"2002","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/j.jchromb.2009.10.030","article-title":"Use of NMR techniques for toxic organophosphorus compound profiling","volume":"878","author":"Koskela","year":"2010","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"PR1","DOI":"10.1021\/acs.chemrev.5b00402","article-title":"Update 1 of: Destruction and detection of chemical warfare agents","volume":"115","author":"Jang","year":"2015","journal-title":"Chem. Rev."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1364\/JOSAB.10.000283","article-title":"Photonic band-gap structure","volume":"10","author":"Yablonovitch","year":"1993","journal-title":"J. Opt. Soc. Am. B"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"6087","DOI":"10.1039\/c3tc30722k","article-title":"Photonic crystal for gas sensing","volume":"1","author":"Xu","year":"2013","journal-title":"J. Mater. Chem. C"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1002\/anie.201307828","article-title":"Photonic crystals for chemical sensing and biosensing","volume":"53","author":"Fenzl","year":"2014","journal-title":"Angew. Chem. Int. Ed."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"842425","DOI":"10.1117\/12.921784","article-title":"Unexplained high sensitivity of the reflectance of porous natural photonic structures to the presence of gases and vapours in the atmosphere","volume":"8424","author":"Mouchet","year":"2012","journal-title":"Proc. SPIE"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"12267","DOI":"10.1364\/OE.24.012267","article-title":"Vapor sensing with a natural photonic cell","volume":"24","author":"Mouchet","year":"2016","journal-title":"Opt. Express"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"M\u00e1rk, G.I., Kert\u00e9sz, K., Piszter, G., B\u00e1lint, Z., and Bir\u00f3, L.P. (2019). Modeling the reflectance changes induced by vapor condensation in Lycaenid butterfly wing scales colored by photonic nanoarchitectures. Nanomaterials, 9.","DOI":"10.3390\/nano9050759"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/nphoton.2007.2","article-title":"Morpho butterfly wing scales demonstrate highly selective vapour response","volume":"1","author":"Potyrailo","year":"2007","journal-title":"Nat. Photonics"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"15567","DOI":"10.1073\/pnas.1311196110","article-title":"Discovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response","volume":"110","author":"Potyrailo","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"7959","DOI":"10.1038\/ncomms8959","article-title":"Towards outperforming conventional sensor arrays with fabricated individual photonic vapour sensors inspired by Morpho butterflies","volume":"6","author":"Potyrailo","year":"2015","journal-title":"Nat. Commun."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"024006","DOI":"10.1088\/2040-8986\/aa9ecf","article-title":"Multivariable bio-inspired photonic sensors for non-condensable gases","volume":"20","author":"Potyrailo","year":"2018","journal-title":"J. Opt."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"705706","DOI":"10.1117\/12.794910","article-title":"Photonic nanoarchitectures occurring in butterfly scales as selective gas\/vapor sensors","volume":"7057","year":"2008","journal-title":"Proc. SPIE"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"103701","DOI":"10.1063\/1.3486115","article-title":"Biologically inspired humidity sensor based on three-dimensional photonic crystals","volume":"97","author":"Kim","year":"2010","journal-title":"Appl. Phys. Lett."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"3784","DOI":"10.1002\/adfm.201001195","article-title":"Bioinspired water-vapor-responsive organic\/inorganic hybrid one-dimensional photonic crystals with tunable full-color stop band","volume":"20","author":"Wang","year":"2010","journal-title":"Adv. Funct. Mater."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1002\/adfm.201203672","article-title":"Multiple structural coloring of silk-fibroin photonic crystals and humidity-responsive color sensing","volume":"23","author":"Diao","year":"2013","journal-title":"Adv. Funct. Mater."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"11094","DOI":"10.1021\/nn504659p","article-title":"Bio-inspired vapor-responsive colloidal photonic crystal patterns by inkjet printing","volume":"8","author":"Bai","year":"2014","journal-title":"ACS Nano"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"036011","DOI":"10.1088\/1748-3190\/11\/3\/036011","article-title":"Vapour sensitivity of an ALD hierarchical photonic structure inspired by Morpho","volume":"11","author":"Poncelet","year":"2016","journal-title":"Bioinspir. Biomim."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"5006","DOI":"10.1016\/j.matpr.2017.04.107","article-title":"Vapor sensing using a bio-inspired porous silicon photonic crystal","volume":"4","author":"Rasson","year":"2017","journal-title":"Mater. Today Proc."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.msec.2014.03.014","article-title":"Temperature and saturation dependence in the vapor sensing of butterfly wing scales","volume":"39","author":"Piszter","year":"2014","journal-title":"Mater. Sci. Eng. C"},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Kert\u00e9sz, K., Piszter, G., B\u00e1lint, Z., and Bir\u00f3, L.P. (2018). Optical vapor sensing on single wing scales and on whole wings of the Albulina metallica butterfly. Sensors, 18.","DOI":"10.3390\/s18124282"},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Piszter, G., Kert\u00e9sz, K., B\u00e1lint, Z., and Bir\u00f3, L.P. (2019). Optical detection of vapor mixtures using structurally colored butterfly and moth wings. Sensors, 19.","DOI":"10.3390\/s19143058"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"5399","DOI":"10.1021\/ja0006200","article-title":"Detection of fluorophosphonate chemical warfare agents by catalytic hydrolysis with a porous silicon interferometer","volume":"122","author":"Sohn","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1021\/ac048562e","article-title":"Acetylcholinesterase-based organophosphate nerve agent sensing photonic crystal","volume":"77","author":"Walker","year":"2005","journal-title":"Anal. Chem."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1007\/s00216-007-1599-y","article-title":"Photonic crystal sensor for organophosphate nerve agents utilizing the organophosphorus hydrolase enzyme","volume":"389","author":"Walker","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1002\/adfm.200701494","article-title":"Humidity-compensating sensor for volatile organic compounds using stacked porous silicon photonic crystals","volume":"18","author":"Ruminski","year":"2008","journal-title":"Adv. Funct. Mater."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.matlet.2007.06.009","article-title":"Detection of organophosphates based on surface-modified DBR porous silicon using LED light","volume":"62","author":"Jang","year":"2008","journal-title":"Mater. Lett."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1186\/1556-276X-7-527","article-title":"Detection of nerve agent stimulants based on photoluminescent porous silicon interferometer","volume":"7","author":"Kim","year":"2012","journal-title":"Nanoscale Res. Lett."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.talanta.2016.06.045","article-title":"Functionalized photonic crystal for the sensing of Sarin agents","volume":"159","author":"Yan","year":"2016","journal-title":"Talanta"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"8301","DOI":"10.1021\/acsomega.7b01680","article-title":"Sensing chemical warfare agent simulants via photonic crystals of the Morpho didius butterfly","volume":"2","author":"Kittle","year":"2017","journal-title":"ACS Omega"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"29385","DOI":"10.1039\/C8RA04953J","article-title":"Acetylcholinestrerase-functionalized two-dimensional crystals for the detection of organophosphates","volume":"8","author":"Qi","year":"2018","journal-title":"RSC Adv."},{"key":"ref_33","unstructured":"Berthier, S. (2003). Iridescences, les Couleurs Physiques des Insectes, Springer."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"6133","DOI":"10.1039\/C4NR00477A","article-title":"Spectral selectivity of 3D magnetophotonic crystal film fabricated from single butterfly wing scales","volume":"6","author":"Peng","year":"2014","journal-title":"Nanoscale"},{"key":"ref_35","unstructured":"Joannopoulos, J.D., Meade, R.D., and Winn, J.N. (1995). Photonic Crystals, Princeton University Press."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev-matsci-071312-121710","article-title":"Bionanomaterials and Bioinspired Nanostructures for Selective Vapor Sensing","volume":"43","author":"Potyrailo","year":"2013","journal-title":"Annu. Rev. Mater. Res."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/1\/157\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:45:43Z","timestamp":1760190343000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/1\/157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,25]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1]]}},"alternative-id":["s20010157"],"URL":"https:\/\/doi.org\/10.3390\/s20010157","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2019,12,25]]}}}