{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:39:29Z","timestamp":1760402369058,"version":"build-2065373602"},"reference-count":19,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006509","name":"VSB Fonds","doi-asserted-by":"publisher","award":["SV450994\/2101"],"award-info":[{"award-number":["SV450994\/2101"]}],"id":[{"id":"10.13039\/501100006509","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014809","name":"Technology Agency of the Czech Republic","doi-asserted-by":"publisher","award":["TL01000302"],"award-info":[{"award-number":["TL01000302"]}],"id":[{"id":"10.13039\/100014809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This paper presents a newly-designed and realized Invasive Blood Pressure (IBP) device for the simulation on patient\u2019s monitors. This device shows improvements and presents extended features with respect to a first prototype presented by the authors and similar systems available in the state-of-the-art. A peculiarity of the presented device is that all implemented features can be customized from the developer and from the point of view of the end user. The realized device has been tested, and its performances in terms of accuracy and of the back-loop measurement of the output for the blood pressure regulation utilization have been described. In particular, an accuracy of \u00b11 mmHg at 25 \u00b0C, on a range from \u221230 to 300 mmHg, was evaluated under different test conditions. The designed device is an ideal tool for testing IBP modules, for zero setting, and for calibrations. The implemented extended features, like the generation of custom waveforms and the Universal Serial Bus (USB) connectivity, allow use of this device in a wide range of applications, from research to equipment maintenance in clinical environments to educational purposes. Moreover, the presented device represents an innovation, both in terms of technology and methodologies: It allows quick and efficient tests to verify the proper functioning of IBP module of patients\u2019 monitors. With this innovative device, tests can be performed directly in the field and faster procedures can be implemented by the clinical maintenance personnel. This device is an open source project and all materials, hardware, and software are fully available for interested developers or researchers.<\/jats:p>","DOI":"10.3390\/s20010259","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T04:43:03Z","timestamp":1578026583000},"page":"259","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Design and Development of a Novel Invasive Blood Pressure Simulator for Patient\u2019s Monitor Testing"],"prefix":"10.3390","volume":"20","author":[{"given":"Daniele","family":"Bibbo","sequence":"first","affiliation":[{"name":"Department of Engineering, University of Roma Tre, Via Vito Volterra, 62, 00146 Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Kijonka","sequence":"additional","affiliation":[{"name":"Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava, 17. listopadu 2172\/15, 708 00 Ostrava\u2013Poruba, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4872-9362","authenticated-orcid":false,"given":"Petr","family":"Kudrna","sequence":"additional","affiliation":[{"name":"Department of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, nam. Sitna 3105, 272 01 Kladno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Penhaker","sequence":"additional","affiliation":[{"name":"Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava, 17. listopadu 2172\/15, 708 00 Ostrava\u2013Poruba, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petr","family":"Vavra","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital in Ostrava, 17. Listopadu 1790, 70852 Ostrava, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pavel","family":"Zonca","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University Hospital in Ostrava, 17. Listopadu 1790, 70852 Ostrava, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1177\/108925320500900404","article-title":"Simulation devices in cardiothoracic and vascular anesthesia","volume":"9","author":"Eason","year":"2005","journal-title":"Semin. Cardiothorac. Vasc. Anesth."},{"key":"ref_2","first-page":"12","article-title":"Improving patient safety through simulation training in anesthesiology: Where are we?","volume":"2016","author":"Green","year":"2016","journal-title":"Anesthesiol. Res. Pract."},{"key":"ref_3","first-page":"16","article-title":"Biomedical engineering education under european union support","volume":"35","author":"AbuOsman","year":"2011","journal-title":"5th Kuala Lumpur International Conference on Biomedical Engineering"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1152\/advan.00109.2018","article-title":"Making the clinical connection from textbook to bedside during MDY1: An integrative approach for medical physiology education employing human simulation","volume":"43","author":"Johnson","year":"2019","journal-title":"Adv. Physiol. Educ."},{"key":"ref_5","unstructured":"Fox, F. (1982). Method and Apparatus for Zeroing and Calibrating an Invasive Blood Pressure Monitoring System. (No. 4,342,218), U.S. Patent."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"44","DOI":"10.5369\/JSST.2007.16.1.044","article-title":"Blood pressure simulator using hybrid controller","volume":"16","author":"Kim","year":"2007","journal-title":"J. Sens. Sci. Technol."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Krejcar, O., Slanina, Z., Stambachr, J., Silber, P., and Frischer, R. (2009, January 20\u201323). Noninvasive continuous blood pressure measurement and GPS position monitoring of patients. Proceedings of the 2009 IEEE 70th Vehicular Technology Conference Fall, Anchorage, AK, USA.","DOI":"10.1109\/VETECF.2009.5378905"},{"key":"ref_8","first-page":"49","article-title":"Electronic invasive blood pressure simulator device for patient monitor testing","volume":"122","author":"Kijonka","year":"2012","journal-title":"Elektron. Elektrotechnika"},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Penhaker, M., and Kijonka, J. (2011). Invasive blood pressure simulator electronics device bed side monitor testing. Electrical Power Systems and Computers, Springer.","DOI":"10.1007\/978-3-642-21747-0_106"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Kijonka, J., Penhaker, M., and Cernohorsky, J. (2011). Invasive blood pressure curves simulation device. 2011 1st Middle East Conference on Biomedical Engineering, IEEE.","DOI":"10.1109\/MECBME.2011.5752098"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Kijonka, J., and Penhaker, M. (2010). Embedded programmable invasive blood pressure simulator. XII Mediterranean Conference on Medical and Biological Engineering and Computing, Springer.","DOI":"10.1007\/978-3-642-13039-7_224"},{"key":"ref_12","unstructured":"Kijonka, J., and Penhaker, M. (2010). Invasive Blood Pressure Simulator, Testing, Adjusting and Calibration of the Device. [Master\u2019s Thesis, Department of Cybernetics and Biomedical Engineering, Faculty of Electrical Engineering and Computer Science, VSB-Technical University of Ostrava]."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"23095","DOI":"10.3390\/s150923095","article-title":"Pre-processing effect on the accuracy of event-based activity segmentation and classification through inertial sensors","volume":"15","author":"Fida","year":"2015","journal-title":"Sensors"},{"key":"ref_14","unstructured":"(2019, December 31). NovaSensor Disposable Medical Pressure Sensor NPC-100 and NPC-120 Series. Available online: http:\/\/www.amphenol-sensors.com\/en\/products\/pressure-mems\/mems-sensors\/3150-npc-100-and-120-series#features."},{"key":"ref_15","first-page":"325","article-title":"Qualitative modeling at the design of concrete manufacturing machinery","volume":"30","author":"Garani","year":"2008","journal-title":"Int. J. Comput. Appl."},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Proto, A., Bibbo, D., Conforto, S., and Schmid, M. (2014, January 22\u201324). A new microcontroller-based system to optimize the digital conversion of signals originating from load cells built-in into pedals. Proceedings of the IEEE 2014 Biomedical Circuits and Systems Conference (BioCAS), Lausanne, Switzerland.","DOI":"10.1109\/BioCAS.2014.6981722"},{"key":"ref_17","first-page":"249","article-title":"Bio-amplifier with programmable gain and adjustable leads for basic measurement of bioelectric signals","volume":"4","author":"Pietka","year":"2014","journal-title":"Information Technologies in Biomedicine"},{"key":"ref_18","first-page":"65","article-title":"Bluetooth communication for battery powered medical devices","volume":"67","author":"Babusiak","year":"2016","journal-title":"J. Electr. Eng. Elektrotech. Cas."},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Babusiak, B., and Borik, S. (2015, January 9\u201311). Low energy wireless communication for medical devices. Proceedings of the 38th International Conference on Telecommunications and Signal Processing (TSP), Prague, Czech.","DOI":"10.1109\/TSP.2015.7296301"}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/1\/259\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:42:05Z","timestamp":1760362925000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/1\/259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,1]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1]]}},"alternative-id":["s20010259"],"URL":"https:\/\/doi.org\/10.3390\/s20010259","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2020,1,1]]}}}