{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T01:23:27Z","timestamp":1781141007468,"version":"3.54.1"},"reference-count":59,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T00:00:00Z","timestamp":1581379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2221-E-224 -020"],"award-info":[{"award-number":["108-2221-E-224 -020"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["107-2221-E-224 -030"],"award-info":[{"award-number":["107-2221-E-224 -030"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>In this study, the potentiometric arrayed glucose biosensors, which were based on zinc oxide (ZnO) or aluminum-doped zinc oxide (AZO) sensing membranes, were fabricated by using screen-printing technology and a sputtering system, and graphene oxide (GO) and Nafion-glucose oxidase (GOx) were used to modify sensing membranes by using the drop-coating method. Next, the material properties were characterized by using a Raman spectrometer, a field-emission scanning electron microscope (FE-SEM), and a scanning probe microscope (SPM). The sensing characteristics of the glucose biosensors were measured by using the voltage\u2013time (V-T) measurement system. Finally, electrochemical impedance spectroscopy (EIS) was conducted to analyze their charge transfer abilities. The results indicated that the average sensitivity of the glucose biosensor based on Nafion-GOx\/GO\/AZO was apparently higher than that of the glucose biosensor based on Nafion-GOx\/GO\/ZnO. In addition, the glucose biosensor based on Nafion-GOx\/GO\/AZO exhibited an excellent average sensitivity of 15.44 mV\/mM and linearity of 0.997 over a narrow range of glucose concentration range, a response time of 26 s, a limit of detection (LOD) of 1.89 mM, and good reproducibility. In terms of the reversibility and stability, the hysteresis voltages (VH) were 3.96 mV and 2.42 mV. Additionally, the glucose biosensor also showed good anti-inference ability and reproducibility. According to these results, it is demonstrated that AZO is a promising material, which could be used to develop a reliable, simple, and low-cost potentiometric glucose biosensor.<\/jats:p>","DOI":"10.3390\/s20040964","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T11:45:30Z","timestamp":1581421530000},"page":"964","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["A Facile Fabrication of a Potentiometric Arrayed Glucose Biosensor Based on Nafion-GOx\/GO\/AZO"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8829-3404","authenticated-orcid":false,"given":"Jung-Chuan","family":"Chou","sequence":"first","affiliation":[{"name":"Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Hong","family":"Lin","sequence":"additional","affiliation":[{"name":"Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsu-Yang","family":"Lai","sequence":"additional","affiliation":[{"name":"Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2791-9642","authenticated-orcid":false,"given":"Po-Yu","family":"Kuo","sequence":"additional","affiliation":[{"name":"Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Hsien","family":"Lai","sequence":"additional","affiliation":[{"name":"Graduate School of Electronic Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hsun","family":"Nien","sequence":"additional","affiliation":[{"name":"Graduate School of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzu-Yu","family":"Su","sequence":"additional","affiliation":[{"name":"Graduate School of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Douliu 64002, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.aca.2011.07.024","article-title":"Technology behind commercial devices for blood glucose monitoring in diabetes management: A review","volume":"703","author":"Vashist","year":"2011","journal-title":"Anal. 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