{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T07:13:35Z","timestamp":1780557215955,"version":"3.54.1"},"reference-count":46,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2020,2,29]],"date-time":"2020-02-29T00:00:00Z","timestamp":1582934400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006360","name":"Bundesministerium f\u00fcr Wirtschaft und Energie","doi-asserted-by":"publisher","award":["VP2146336CS4"],"award-info":[{"award-number":["VP2146336CS4"]}],"id":[{"id":"10.13039\/501100006360","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002723","name":"Allianz Industrie Forschung","doi-asserted-by":"publisher","award":["19364 N"],"award-info":[{"award-number":["19364 N"]}],"id":[{"id":"10.13039\/501100002723","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Inkjet technology as a maskless, direct-writing technology offers the potential for structured deposition of functional materials for the realization of electrodes for, e.g., sensing applications. In this work, electrodes were realized by inkjet-printing of commercial nanoparticle gold ink on planar substrates and, for the first time, onto the 2.5D surfaces of a 0.5 mm-deep microfluidic chamber produced in cyclic olefin copolymer (COC). The challenges of a poor wetting behavior and a low process temperature of the COC used were solved by a pretreatment with oxygen plasma and the combination of thermal (130 \u00b0C for 1 h) and photonic (955 mJ\/cm\u00b2) steps for sintering. By performing the photonic curing, the resistance could be reduced by about 50% to 22.7 \u00b5\u2126 cm. The printed gold structures were mechanically stable (optimal cross-cut value) and porous (roughness factors between 8.6 and 24.4 for 3 and 9 inkjet-printed layers, respectively). Thiolated DNA probes were immobilized throughout the porous structure without the necessity of a surface activation step. Hybridization of labeled DNA probes resulted in specific signals comparable to signals on commercial screen-printed electrodes and could be reproduced after regeneration. The process described may facilitate the integration of electrodes in 2.5D lab-on-a-chip systems.<\/jats:p>","DOI":"10.3390\/s20051333","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T03:13:28Z","timestamp":1583205208000},"page":"1333","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Inkjet-Printing of Nanoparticle Gold and Silver Ink on Cyclic Olefin Copolymer for DNA-Sensing Applications"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7495-1939","authenticated-orcid":false,"given":"Martin","family":"Trotter","sequence":"first","affiliation":[{"name":"Hahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0549-5407","authenticated-orcid":false,"given":"Daniel","family":"Juric","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Allmandring 9b, 70569 Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Bagherian","sequence":"additional","affiliation":[{"name":"Laboratory for MEMS Applications, IMTEK\u2014Department of Microsystems Engineering, University of Freiburg, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Borst","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"},{"name":"Laboratory for MEMS Applications, IMTEK\u2014Department of Microsystems Engineering, University of Freiburg, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Gl\u00e4ser","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Allmandring 9b, 70569 Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Meissner","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Allmandring 9b, 70569 Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"von Stetten","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"},{"name":"Laboratory for MEMS Applications, IMTEK\u2014Department of Microsystems Engineering, University of Freiburg, Georges-Koehler-Allee 103, 79110 Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1824-9376","authenticated-orcid":false,"given":"Andr\u00e9","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Hahn-Schickard, Allmandring 9b, 70569 Stuttgart, Germany"},{"name":"Institute for Micro Integration IFM, University of Stuttgart, Allmandring 9b, 70569 Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,2,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Kaka\u00e7, S., Kosoy, B., Li, D., and Pramuanjaroenkij, A. 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