{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:29:49Z","timestamp":1767706189813,"version":"build-2065373602"},"reference-count":36,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T00:00:00Z","timestamp":1590624000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"South Korea's Ministry of Trade, Industry and Energy","award":["R0004491"],"award-info":[{"award-number":["R0004491"]}]},{"DOI":"10.13039\/501100002462","name":"Chungnam National University","doi-asserted-by":"publisher","award":["Research fund"],"award-info":[{"award-number":["Research fund"]}],"id":[{"id":"10.13039\/501100002462","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Monitoring cerebral circulation during cardiopulmonary resuscitation (CPR) is essential to improve patients\u2019 prognosis and quality of life. We assessed the feasibility of non-invasive electroencephalography (EEG) parameters as predictive factors of cerebral resuscitation in a ventricular fibrillation (VF) swine model. After 1 min untreated VF, four cycles of basic life support were performed and the first defibrillation was administered. Sustained return of spontaneous circulation (ROSC) was confirmed if a palpable pulse persisted for 20 min. Otherwise, one cycle of advanced cardiovascular life support (ACLS) and defibrillation were administered immediately. Successfully defibrillated animals were continuously monitored. If sustained ROSC was not achieved, another cycle of ACLS was administered. Non-ROSC was confirmed when sustained ROSC did not occur after 10 ACLS cycles. EEG and hemodynamic parameters were measured during experiments. Data measured for approximately 3 s right before the defibrillation attempts were analyzed to investigate the relationship between the recovery of carotid blood flow (CBF) and non-invasive EEG parameters, including time- and frequency-domain parameters and entropy indices. We found that time-domain magnitude and entropy measures of EEG correlated with the change of CBF. Further studies are warranted to evaluate these EEG parameters as potential markers of cerebral circulation during CPR.<\/jats:p>","DOI":"10.3390\/s20113052","type":"journal-article","created":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T12:36:58Z","timestamp":1590669418000},"page":"3052","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Frontal EEG Changes with the Recovery of Carotid Blood Flow in a Cardiac Arrest Swine Model"],"prefix":"10.3390","volume":"20","author":[{"given":"Heejin","family":"Kim","sequence":"first","affiliation":[{"name":"Interdisciplinary Program in Bioengineering, Graduate School, Seoul National University, Seoul 03080, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2115-0078","authenticated-orcid":false,"given":"Ki Hong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Seoul National University Hospital, Seoul 03080, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Jeong","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Seoul National University Hospital, Seoul 03080, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2737-4427","authenticated-orcid":false,"given":"Yunseo","family":"Ku","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Chungnam National University College of Medicine, 266, Munwha-ro, Jung-gu, Deajeon 35015, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Do","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Seoul National University Hospital, Seoul 03080, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2112-426X","authenticated-orcid":false,"given":"Hee Chan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul 03080, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,5,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e146","DOI":"10.1161\/CIR.0000000000000485","article-title":"Heart disease and stroke statistics-2017 update: A report from the American Heart Association","volume":"135","author":"Benjamin","year":"2017","journal-title":"Circulation"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1161\/CIRCULATIONAHA.114.009711","article-title":"Recent trends in survival from out-of-hospital cardiac arrest in the United States","volume":"130","author":"Chan","year":"2014","journal-title":"Circulation"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.resuscitation.2015.02.003","article-title":"Out-of-hospital cardiac arrest survival improving over time: Results from the Resuscitation Outcomes Consortium (ROC)","volume":"91","author":"Daya","year":"2015","journal-title":"Resuscitation"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1161\/01.CIR.83.5.1832","article-title":"Improving survival from sudden cardiac arrest: The \u201cchain of survival\u201d concept. 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