{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T02:55:21Z","timestamp":1760237721520,"version":"build-2065373602"},"reference-count":39,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2020,6,10]],"date-time":"2020-06-10T00:00:00Z","timestamp":1591747200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013349","name":"Lungenliga Schweiz","doi-asserted-by":"publisher","award":["OxySmart project"],"award-info":[{"award-number":["OxySmart project"]}],"id":[{"id":"10.13039\/501100013349","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Current oxygen delivery modes lack monitoring and can be cumbersome for patients with chronic respiratory diseases. Integrating a pulse oximeter and nasal oxygen cannulas into eyeglasses would reduce the burden of current solutions. An ear pulse oximeter (OxyFrame) was evaluated on 16 healthy volunteers and 20 hypoxemic patients with chronic respiratory diseases undergoing a prespecified protocol simulating daily activities. Correlation, error, and accuracy root mean square error (ARMS) were calculated to compare SpO2 measured by OxyFrame, a standard pulse oximeter (MASIMO), and arterial blood gas analysis (aBGA). SpO2 measured by OxyFrame and MASIMO correlated strongly in volunteers, with low error and high accuracy (r = 0.85, error = 0.2 \u00b1 2.9%, ARMS = 2.88%). Performances were similar in patients (r = 0.87, error 0 \u00b1 2.5%, ARMS = 2.49% compared with MASIMO; and r = 0.93, error = 0.4 \u00b1 1.9%, ARMS = 1.94% compared with aBGA). However, the percentage of rejected measurements was high (volunteers 77.2%, patients 46.9%). The OxyFrame cavum conchae pulse oximeter was successfully evaluated, and demonstrated accurate SpO2 measurements, compliant with ISO 80601-2-61:2017. Several reasons for the high rejection rate were identified, and potential solutions were proposed, which might be valuable for optimization of the sensor hardware.<\/jats:p>","DOI":"10.3390\/s20113301","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T05:56:27Z","timestamp":1592200587000},"page":"3301","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of a Novel Ear Pulse Oximeter: Towards Automated Oxygen Titration in Eyeglass Frames"],"prefix":"10.3390","volume":"20","author":[{"given":"Fabian","family":"Braun","sequence":"first","affiliation":[{"name":"Centre Suisse d\u2032Electronique et de Microtechnique (CSEM), CH-2000 Neuch\u00e2tel, Switzerland"}]},{"given":"Christophe","family":"Verjus","sequence":"additional","affiliation":[{"name":"Centre Suisse d\u2032Electronique et de Microtechnique (CSEM), CH-2000 Neuch\u00e2tel, Switzerland"}]},{"given":"Josep","family":"Sol\u00e0","sequence":"additional","affiliation":[{"name":"Centre Suisse d\u2032Electronique et de Microtechnique (CSEM), CH-2000 Neuch\u00e2tel, Switzerland"}]},{"given":"Marcus","family":"Marienfeld","sequence":"additional","affiliation":[{"name":"Marcus Marienfeld AG, CH-3911 Ried-Brig, Switzerland"}]},{"given":"Manuela","family":"Funke-Chambour","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland"}]},{"given":"Jens","family":"Krauss","sequence":"additional","affiliation":[{"name":"Centre Suisse d\u2032Electronique et de Microtechnique (CSEM), CH-2000 Neuch\u00e2tel, Switzerland"}]},{"given":"Thomas","family":"Geiser","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9833-5911","authenticated-orcid":false,"given":"Sabina A.","family":"Guler","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland"}]}],"member":"1968","published-online":{"date-parts":[[2020,6,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1900164","DOI":"10.1183\/13993003.00164-2019","article-title":"Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The GOLD science committee report 2019","volume":"53","author":"Singh","year":"2019","journal-title":"Eur. 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