{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T14:51:04Z","timestamp":1780498264225,"version":"3.54.1"},"reference-count":19,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Rational drug design is an approach based on detailed knowledge of molecular interactions and dynamic of bio-molecules. This approach involves designing new digital and interactive tools including classical desktop interaction devices as well as advanced ones such as haptic arms or virtual reality devices. These approaches however struggle to deal with flexibility of bio-molecules by simultaneously steering the numerous degrees of freedom. We propose a new method that follows a direct interaction approach by implementing an innovative methodology benefiting from a physical, modular and articulated molecular interface augmented by wireless embedded sensors. The goal is to create, design and steer its in silico twin virtual model and better interact with dynamic molecular models.<\/jats:p>","DOI":"10.3390\/s20185415","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T21:01:21Z","timestamp":1600722081000},"page":"5415","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Physical, Modular and Articulated Interface for Interactive Molecular Manipulation"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4770-4238","authenticated-orcid":false,"given":"Bastien","family":"Vincke","sequence":"first","affiliation":[{"name":"SATIE\u2014CNRS UMR 8029, Univ. Paris-Saclay, Digiteo Labs, BAT 660, 91405 Orsay CEDEX, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Anis","family":"Ghaoui","sequence":"additional","affiliation":[{"name":"SATIE\u2014CNRS UMR 8029, Univ. 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