{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T07:12:29Z","timestamp":1769152349003,"version":"3.49.0"},"reference-count":44,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fondazione G.B. Baroni","award":["ReSTART project"],"award-info":[{"award-number":["ReSTART project"]}]},{"name":"H2020 CONBOTS","award":["ICT-871803"],"award-info":[{"award-number":["ICT-871803"]}]},{"name":"INFANTPATTERNS","award":["H2020-MSCA-IF-846679"],"award-info":[{"award-number":["H2020-MSCA-IF-846679"]}]},{"name":"MRC Clinician Scientist Fellowship","award":["MR\/P008712\/1"],"award-info":[{"award-number":["MR\/P008712\/1"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Grasping is one of the first dominant motor behaviors that enable interaction of a newborn infant with its surroundings. Although atypical grasping patterns are considered predictive of neuromotor disorders and injuries, their clinical assessment suffers from examiner subjectivity, and the neuropathophysiology is poorly understood. Therefore, the combination of technology with functional magnetic resonance imaging (fMRI) may help to precisely map the brain activity associated with grasping and thus provide important insights into how functional outcomes can be improved following cerebral injury. This work introduces an MR-compatible device (i.e., smart graspable device (SGD)) for detecting grasping actions in newborn infants. Electromagnetic interference immunity (EMI) is achieved using a fiber Bragg grating sensor. Its biocompatibility and absence of electrical signals propagating through the fiber make the safety profile of the SGD particularly favorable for use with fragile infants. Firstly, the SGD design, fabrication, and metrological characterization are described, followed by preliminary assessments on a preterm newborn infant and an adult during an fMRI experiment. The results demonstrate that the combination of the SGD and fMRI can safely and precisely identify the brain activity associated with grasping behavior, which may enable early diagnosis of motor impairment and help guide tailored rehabilitation programs.<\/jats:p>","DOI":"10.3390\/s20216040","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T03:51:47Z","timestamp":1603684307000},"page":"6040","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["An fMRI Compatible Smart Device for Measuring Palmar Grasping Actions in Newborns"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1507-231X","authenticated-orcid":false,"given":"Daniela","family":"Lo Presti","sequence":"first","affiliation":[{"name":"Unit of Measurements and Biomedical Instrumentation, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0840-140X","authenticated-orcid":false,"given":"Sofia","family":"Dall\u2019Orso","sequence":"additional","affiliation":[{"name":"Division of Signal Processing and Biomedical Engineering, Department of Electrical Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden"},{"name":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London WC2R 2LS, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0310-1021","authenticated-orcid":false,"given":"Silvia","family":"Muceli","sequence":"additional","affiliation":[{"name":"Division of Signal Processing and Biomedical Engineering, Department of Electrical Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden"},{"name":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London WC2R 2LS, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3550-1644","authenticated-orcid":false,"given":"Tomoki","family":"Arichi","sequence":"additional","affiliation":[{"name":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London WC2R 2LS, UK"},{"name":"Paediatric Neurosciences, Evelina London Children\u2019s Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London SE1 7EH, UK"}]},{"given":"Sara","family":"Neumane","sequence":"additional","affiliation":[{"name":"Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King\u2019s College London, London WC2R 2LS, UK"},{"name":"NeuroDiderot Unit UMR1141, Universit\u00e9 de Paris, INSERM, F-75019 Paris, France"},{"name":"UNIACT, Universit\u00e9 Paris-Saclay, CEA, NeuroSpin, F-91191 Gif-sur-Yvette, France"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4508-3439","authenticated-orcid":false,"given":"Anna","family":"Lukens","sequence":"additional","affiliation":[{"name":"Paediatric Neurosciences, Evelina London Children\u2019s Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London SE1 7EH, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3574-9842","authenticated-orcid":false,"given":"Riccardo","family":"Sabbadini","sequence":"additional","affiliation":[{"name":"Unit of Measurements and Biomedical Instrumentation, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3090-5623","authenticated-orcid":false,"given":"Carlo","family":"Massaroni","sequence":"additional","affiliation":[{"name":"Unit of Measurements and Biomedical Instrumentation, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5728-3123","authenticated-orcid":false,"given":"Michele Arturo","family":"Caponero","sequence":"additional","affiliation":[{"name":"Photonics Micro- and Nanostructures Laboratory, ENEA Research Center of Frascati, 00044 Frascati (RM), Italy"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0240-1265","authenticated-orcid":false,"given":"Domenico","family":"Formica","sequence":"additional","affiliation":[{"name":"Unit of Neurophysiology and Neuroengineering of Human-Technology Interaction (NeXt Lab), Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy"}]},{"given":"Etienne","family":"Burdet","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Imperial College London, London SW7 2AZ, UK"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9696-1265","authenticated-orcid":false,"given":"Emiliano","family":"Schena","sequence":"additional","affiliation":[{"name":"Unit of Measurements and Biomedical Instrumentation, Universit\u00e0 Campus Bio-Medico di Roma, Via Alvaro del Portillo, 00128 Rome, Italy"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Lejeune, F., Audeoud, F., Marcus, L., Streri, A., Debillon, T., and Gentaz, E. 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