{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:54:44Z","timestamp":1762005284321,"version":"build-2065373602"},"reference-count":52,"publisher":"MDPI AG","issue":"21","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","award":["313039, 328226, 328214"],"award-info":[{"award-number":["313039, 328226, 328214"]}],"id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Union","doi-asserted-by":"publisher","award":["CZ.02.2.69\/0.0\/0.0\/16_027\/00083710"],"award-info":[{"award-number":["CZ.02.2.69\/0.0\/0.0\/16_027\/00083710"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003406","name":"Finnish Funding Agency for Innovation","doi-asserted-by":"publisher","award":["5G VIIMA"],"award-info":[{"award-number":["5G VIIMA"]}],"id":[{"id":"10.13039\/501100003406","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The integration of millimeter wave (mmWave) and low frequency interfaces brings an unique opportunity to unify the communications and positioning technologies in the future wireless heterogeneous networks (HetNets), which offer great potential for efficient handover using location awareness, hence a location-aware handover (LHO). Targeting a self-organized communication system with autonomous vehicles, we conduct and describe an experimental and analytical study on the LHO using a mmWave-enabled robotic platform in a multi-radio environment. Compared to the conventional received signal strength indicator (RSSI)-based handover, the studied LHO not only improves the achievable throughput, but also enhances the wireless link robustness for the industrial Internet-of-things (IIoT)-oriented applications. In terms of acquiring location awareness, a geometry-based positioning (GBP) algorithm is proposed and implemented in both simulation and experiments, where its achievable accuracy is assessed and tested. Based on the performed experiments, the location-related measurements acquired by the robot are not accurate enough for the standalone-GBP algorithm to provide an accurate location awareness to perform a reliable handover. Nevertheless, we demonstrate that by combining the GBP with the dead reckoning, more accurate location awareness becomes achievable, the LHO can therefore be performed in a more optimized manner compared to the conventional RSSI-based handover scheme, and is therefore able to achieve approximately twice as high average throughput in certain scenarios. Our study confirms that the achieved location awareness, if accurate enough, could enable an efficient handover scheme, further enhancing the autonomous features in the HetNets.<\/jats:p>","DOI":"10.3390\/s20216290","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:37Z","timestamp":1604534437000},"page":"6290","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Feasibility of Location-Aware Handover for Autonomous Vehicles in Industrial Multi-Radio Environments"],"prefix":"10.3390","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8279-8372","authenticated-orcid":false,"given":"Yi","family":"Lu","sequence":"first","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9151-0214","authenticated-orcid":false,"given":"Mikhail","family":"Gerasimenko","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"},{"name":"Department of Telecommunications, Brno University of Technology, 616 00 Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Kovalchukov","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Stusek","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"},{"name":"Department of Telecommunications, Brno University of Technology, 616 00 Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9113-8483","authenticated-orcid":false,"given":"Jani","family":"Urama","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8382-9185","authenticated-orcid":false,"given":"Jiri","family":"Hosek","sequence":"additional","affiliation":[{"name":"Department of Telecommunications, Brno University of Technology, 616 00 Brno, Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikko","family":"Valkama","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1718-6924","authenticated-orcid":false,"given":"Elena Simona","family":"Lohan","sequence":"additional","affiliation":[{"name":"Department of Electrial Engineering, Tampere University, 33720 Tampere, Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2020,11,5]]},"reference":[{"key":"ref_1","unstructured":"(2015, September 01). ITU-R M.1645. Framework and Overall Objectives of the Future Development of IMT-2000 and System Beyond IMT-2000. Available online: https:\/\/www.itu.int\/dms_pubrec\/itu-r\/rec\/m\/R-REC-M2083-0-201509-I!!PDF-E.pdf."},{"key":"ref_2","unstructured":"(2013, September 01). 3GPP, TR 36.819 V11.2.0. Coordinated Multi-Point Operation for LTE Physical Layer Aspects (Release 11). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=2498."},{"key":"ref_3","unstructured":"(2014, January 01). 3GPP, TR 36.842 V12.0.0. Study on Small Cell Enhancements for E-UTRA and E-UTRAN; Higher Layer aspects (Release 12). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=2543."},{"key":"ref_4","unstructured":"(2020, October 01). 3GPP, TR 37.340 V15.5.0. NR; Multi-Connecitivty; Overall Description; Stage 2 (Release 15). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=3198."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Giordani, M., Mezzavilla, M., Rangan, S., and Zorzi, M. (2016, January 20\u201322). Multi-connectivity in 5G mmWave cellular networks. Proceedings of the 2016 Mediterranean Ad Hoc Networking Workshop (Med-Hoc-Net), Vilanova i la Geltru, Spain.","DOI":"10.1109\/MedHocNet.2016.7528494"},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Bi, T., and Muntean, G. (2017, January 1\u20134). Location-aware network selection mechanism in heterogeneous wireless networks. Proceedings of the 2017 IEEE Conference on Computer Communications Workshops (INFOCOM WKSHPS), Atlanta, GA, USA.","DOI":"10.1109\/INFCOMW.2017.8116442"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"5327","DOI":"10.1109\/TVT.2014.2379953","article-title":"A Fast Cloud-Based Network Selection Scheme Using Coalition Formation Games in Vehicular Networks","volume":"64","author":"Xu","year":"2015","journal-title":"IEEE Trans. Veh. Technol."},{"key":"ref_8","unstructured":"Liu, C., Xia, W., Chen, G., and Shen, L. (2013, January 24\u201326). Location-aware handover decision algorithm in multi-cell networks. Proceedings of the 2013 International Conference on Wireless Communications and Signal Processing, Hangzhou, China."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Kuboniwa, J., Miyake, Y., Kameda, S., Taira, A., Oguma, H., Suematsu, N., Takagi, T., and Tsubouchi, K. (2015, January 9\u201312). High efficient network selection scheme using location information for heterogeneous wireless system. Proceedings of the 2015 IEEE Wireless Communications and Networking Conference Workshops (WCNCW), New Orleans, LA, USA.","DOI":"10.1109\/WCNCW.2015.7122587"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"9456","DOI":"10.1109\/JSEN.2019.2925637","article-title":"A Location Aware Fast PMIPv6 for Low Latency Wireless Sensor Networks","volume":"19","author":"Kang","year":"2019","journal-title":"IEEE Sens. J."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.1109\/TVT.2017.2778065","article-title":"Dual-Connectivity Prevenient Handover Scheme in Control\/User-Plane Split Networks","volume":"67","author":"Hsieh","year":"2018","journal-title":"IEEE Trans. Veh. Technol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"164256","DOI":"10.1109\/ACCESS.2019.2952737","article-title":"A Seamless Handover Scheme With Assisted eNB for 5G C\/U Plane Split Heterogeneous Network","volume":"7","author":"Zhang","year":"2019","journal-title":"IEEE Access"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1109\/TCOMM.2018.2877326","article-title":"Managing Vertical Handovers in Millimeter Wave Heterogeneous Networks","volume":"67","author":"Zang","year":"2019","journal-title":"IEEE Trans. Commun."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"4873","DOI":"10.1109\/TWC.2019.2930193","article-title":"Machine Learning-Based Handovers for Sub-6 GHz and mmWave Integrated Vehicular Networks","volume":"18","author":"Yan","year":"2019","journal-title":"IEEE Trans. Wirel. Commun."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1109\/JPROC.2019.2897155","article-title":"Scaling Millimeter-Wave Networks to Dense Deployments and Dynamic Environments","volume":"107","author":"Fiandrino","year":"2019","journal-title":"Proc. IEEE"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"38285","DOI":"10.1109\/ACCESS.2018.2853730","article-title":"QoE-Aware Intelligent Vertical Handoff Scheme Over Heterogeneous Wireless Access Networks","volume":"6","author":"Chen","year":"2018","journal-title":"IEEE Access"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"96719","DOI":"10.1109\/ACCESS.2019.2929525","article-title":"Theoretical Analysis of REM-Based Handover Algorithm for Heterogeneous Networks","volume":"7","author":"He","year":"2019","journal-title":"IEEE Access"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Lembo, S., Horsmanheimo, S., and Laukkanen, M. (2019, January 28\u201330). Positioning Based Intra-Frequency Handover in Indoor Cellular Network for Ultra Reliable Communications Assisted by Radio Maps. Proceedings of the 2019 11th International Congress on Ultra Modern Telecommunications and Control Systems and Workshops (ICUMT), Dublin, Ireland.","DOI":"10.1109\/ICUMT48472.2019.8970774"},{"key":"ref_19","unstructured":"Erisson (2019). Cellular IoT Evolution for Industry Digitalization, Erisson. White Paper."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Abari, O., Bharadia, D., Duffield, A., and Katabi, D. (2016, January 9). Cutting the cord in virtual reality. Proceedings of the 15th ACM Workshop on Hot Topics in Networks, Atlanta, GA, USA.","DOI":"10.1145\/3005745.3005770"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1109\/SURV.2013.082713.00141","article-title":"Enabling Vertical Handover Decisions in Heterogeneous Wireless Networks: A State-of-the-Art and A Classification","volume":"16","author":"Ahmed","year":"2014","journal-title":"IEEE Commun. Surv. Tutor."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"118907","DOI":"10.1109\/ACCESS.2019.2937405","article-title":"A Survey on Handover Management: From LTE to NR","volume":"7","author":"Tayyab","year":"2019","journal-title":"IEEE Access"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1007\/s11277-015-2904-2","article-title":"A Survey of Context Aware Vertical Handover Management Schemes in Heterogeneous Wireless Networks","volume":"85","author":"Khan","year":"2015","journal-title":"Wirel. Pers. Commun."},{"key":"ref_24","unstructured":"Prasad, R.V., Niemieeger, I., and Nguyen, T.V.H. (2010, January 11\u201313). A study on handoff issues in radio over fiber network at 60 GHz. Proceedings of the International Conference on Communications and Electronics 2010, Nha Trang, Vietnam."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Al-Ammar, M.A., Alhadhrami, S., Al-Salman, A., Alarifi, A., Al-Khalifa, H., Alnafessah, A., and Alsaleh, M. (2014, January 6\u20138). Comparative Survey of Indoor Positioning Technologies, Techniques, and Algorithms. Proceedings of the 2014 International Conference on Cyberworlds (CW), Santander, Spain.","DOI":"10.1109\/CW.2014.41"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Brena, R.F., Garc\u00eda-V\u00e1zquez, J.P., Galv\u00e1n-Tejada, C.E., Mu\u00f1oz-Rodriguez, D., Vargas-Rosales, C., and Fangmeyer, J. (2017). Evolution of indoor positioning technologies: A survey. J. Sens., 2017.","DOI":"10.1155\/2017\/2630413"},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Zekavat, R., and Buehrer, R.M. (2019). Handbook of Position Location: Theory, Practice and Advances, Wiley-IEEE Press. [2nd ed.].","DOI":"10.1002\/9781119434610"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2906","DOI":"10.1109\/JSEN.2014.2382568","article-title":"SmartPDR: Smartphone-Based Pedestrian Dead Reckoning for Indoor Localization","volume":"15","author":"Kang","year":"2015","journal-title":"IEEE Sens. J."},{"key":"ref_29","unstructured":"(2018, September 01). 3GPP, TR 22.872 V16.0.0. Study on Positioning Use Cases (Release 16). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=3280."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Lu, Y., Richter, P., and Lohan, E.S. (2018, January 26\u201328). Opportunities and Challenges in the Industrial Internet of Things based on 5G Positioning. Proceedings of the 2018 8th International Conference on Localization and GNSS (ICL-GNSS), Guimaraes, Portugal.","DOI":"10.1109\/ICL-GNSS.2018.8440903"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Koivisto, M., Talvitie, J., Costa, M., Lepp\u00e4nen, K., and Valkama, M. (2018, January 15\u201318). Joint cmWave-based multiuser positioning and network synchronization in dense 5G networks. Proceedings of the 2018 IEEE Wireless Communications and Networking Conference (WCNC), Barcelona, Spain.","DOI":"10.1109\/WCNC.2018.8377435"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2837","DOI":"10.1109\/TSP.2014.2313531","article-title":"Cooperative Synchronization in Wireless Networks","volume":"62","author":"Etzlinger","year":"2014","journal-title":"IEEE Trans. Signal Process."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Sand, S., Dammann, A., and Mensing, C. (2014). Positioning in Wireless Communication Systems, John Wiley & Sons Ltd.","DOI":"10.1002\/9781118694114"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Talvitie, J., Levanen, T., Koivisto, M., Pajukoski, K., Renfors, M., and Valkama, M. (2018, January 15\u201318). Positioning of high-speed trains using 5G new radio synchronization signals. Proceedings of the 2018 IEEE Wireless Communications and Networking Conference (WCNC), Barcelona, Spain.","DOI":"10.1109\/WCNC.2018.8377225"},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Lu, Y., Koivisto, M., Talvitie, J., Valkama, M., and Lohan, E.S. (October, January 30). EKF-based and Geometry-based Positioning under Location Uncertainty of Access Nodes in Indoor Environment. Proceedings of the 2019 International Conference on Indoor Positioning and Indoor Navigation (IPIN), Pisa, Italy.","DOI":"10.1109\/IPIN.2019.8911785"},{"key":"ref_36","unstructured":"(2016, June 01). 3GPP, TR 23.714 V14.0.0. Study on Control and User Plane Separation of EPC Nodes (Release 14). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=2963."},{"key":"ref_37","doi-asserted-by":"crossref","unstructured":"Zhao, F., Tian, H., Nie, G., and Wu, H. (2018, January 12\u201314). Received Signal Strength Prediction Based Multi-Connectivity Handover Scheme for Ultra-Dense Networks. Proceedings of the 2018 24th Asia-Pacific Conference on Communications (APCC), Ningbo, China.","DOI":"10.1109\/APCC.2018.8633514"},{"key":"ref_38","unstructured":"(2018, January 01). 3GPP, TR 28.801 V15.0.0. Study on Management and Orchestration of Network Slicing for Next Generation Network (Release 15). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=3091."},{"key":"ref_39","unstructured":"Dahlman, E., Parkvall, S., and Skold, J. (2018). 5G NR: The Next Generation Wireless Access Technology, Elsevier Science."},{"key":"ref_40","doi-asserted-by":"crossref","unstructured":"Dong, X., Zhao, L., Zhao, H., and Pan, C. (2018, January 19\u201321). RAN Slicing-based Handover Scheme in HetNetss. Proceedings of the 2018 IEEE 23rd International Conference on Digital Signal Processing (DSP), Shanghai, China.","DOI":"10.1109\/ICDSP.2018.8631578"},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Feirer, S., and Sauter, T. (2017, January 19\u201321). Seamless handover in industrial WLAN using IEEE 802.11k. Proceedings of the 2017 IEEE 26th International Symposium on Industrial Electronics (ISIE), Edinburgh, UK.","DOI":"10.1109\/ISIE.2017.8001421"},{"key":"ref_42","doi-asserted-by":"crossref","unstructured":"Li, Y., Li, C., Chen, W., Yeh, C., and Wang, K. (2017, January 10\u201313). Enabling seamless WiGig\/WiFi handovers in tri-band wireless systems. Proceedings of the 2017 IEEE 25th International Conference on Network Protocols (ICNP), Toronto, ON, Canada.","DOI":"10.1109\/ICNP.2017.8117571"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Ma, J., Yang, D., Zhang, H., and Gidlund, M. (2017). A Reliable Handoff Mechniasm for Mobile Industrial Wireless Sensor Networks. Sensors, 17.","DOI":"10.3390\/s17081797"},{"key":"ref_44","unstructured":"(2019, June 01). 3GPP, TS 23.402 V16.0.0. Architecture Enhancements for Non-3GPP Accesses (Release 16). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=850."},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Sammour, I., and Chalhoub, G. (2020). Evaluation of Rate Adaptation Algorithms in IEEE 802.11 Networks. Electronics, 9.","DOI":"10.3390\/electronics9091436"},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Khan, M.W., Salman, N., Kemp, A.H., and Mihaylova, L. (2016). Localisation of Sensor Nodes with Hybrid Measurements in Wireless Sensor Networks. Sensors, 16.","DOI":"10.3390\/s16071143"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1109\/MWC.2018.1700320","article-title":"Caching-aided collaborative D2D operation for predictive data dissemination in industrial IoT","volume":"25","author":"Orsino","year":"2018","journal-title":"IEEE Wirel. Commun."},{"key":"ref_48","doi-asserted-by":"crossref","unstructured":"Rastorgueva-Foi, E., Koivisto, M., Valkama, M., Costa, M., and Lepp\u00e4nen, K. (2018, January 26\u201328). Localization and Tracking in mmWave Radio Networks using Beam-Based DoD Measurements. Proceedings of the 2018 8th International Conference on Localization and GNSS (ICL-GNSS), Guimaraes, Portugal.","DOI":"10.1109\/ICL-GNSS.2018.8440914"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"55513","DOI":"10.1109\/ACCESS.2020.2981815","article-title":"Positioning-Aided 3D Beamforming for Enhanced Communications in mmWave Mobile Networks","volume":"8","author":"Lu","year":"2020","journal-title":"IEEE Access"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0925-7721(01)00012-8","article-title":"The point in polygon problem for arbitrary polygons","volume":"20","author":"Hormann","year":"2001","journal-title":"Comput. Geom."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"Zhou, A., Wu, L., Xu, S., Ma, H., Wei, T., and Zhang, X. (2018, January 16\u201319). Following the Shadow: Agile 3-D Beam-Steering for 60 GHz Wireless Networks. Proceedings of the IEEE INFOCOM 2018-IEEE Conference on Computer Communications, Honolulu, HI, USA.","DOI":"10.1109\/INFOCOM.2018.8486399"},{"key":"ref_52","unstructured":"(2018, June 01). 3GPP, TR 38.900 V15.0.0. Study on Channel Model for Frequency Spectrum above 6 GHz (Release 15). Available online: https:\/\/portal.3gpp.org\/desktopmodules\/Specifications\/SpecificationDetails.aspx?specificationId=2991."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/21\/6290\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T10:29:27Z","timestamp":1760178567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/20\/21\/6290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,5]]},"references-count":52,"journal-issue":{"issue":"21","published-online":{"date-parts":[[2020,11]]}},"alternative-id":["s20216290"],"URL":"https:\/\/doi.org\/10.3390\/s20216290","relation":{},"ISSN":["1424-8220"],"issn-type":[{"type":"electronic","value":"1424-8220"}],"subject":[],"published":{"date-parts":[[2020,11,5]]}}}