{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T01:12:07Z","timestamp":1778029927861,"version":"3.51.4"},"reference-count":55,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2020,12,26]],"date-time":"2020-12-26T00:00:00Z","timestamp":1608940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010198","name":"Ministerio de Econom\u00eda, Industria y Competitividad, Gobierno de Espa\u00f1a","doi-asserted-by":"publisher","award":["Grant No. BIO2016-80417-P (AEI\/FEDER, UE)"],"award-info":[{"award-number":["Grant No. BIO2016-80417-P (AEI\/FEDER, UE)"]}],"id":[{"id":"10.13039\/501100010198","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["(IT1271-19)"],"award-info":[{"award-number":["(IT1271-19)"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003451","name":"Euskal Herriko Unibertsitatea","doi-asserted-by":"publisher","award":["Proyectos Colaborativos from the University of the Basque Country UPV\/EHU, BIOPLASMOF (COLAB19\/05)."],"award-info":[{"award-number":["Proyectos Colaborativos from the University of the Basque Country UPV\/EHU, BIOPLASMOF (COLAB19\/05)."]}],"id":[{"id":"10.13039\/501100003451","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020","doi-asserted-by":"publisher","award":["research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement No 778001."],"award-info":[{"award-number":["research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement No 778001."]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner.<\/jats:p>","DOI":"10.3390\/s21010101","type":"journal-article","created":{"date-parts":[[2020,12,27]],"date-time":"2020-12-27T20:52:21Z","timestamp":1609102341000},"page":"101","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Predicting Dimensions in Microfluidic Paper Based Analytical Devices"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2315-9703","authenticated-orcid":false,"given":"Raquel","family":"Catalan-Carrio","sequence":"first","affiliation":[{"name":"Microfluidics Cluster UPV\/EHU, Analytical Microsystems &amp; Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"},{"name":"Microfluidics Cluster UPV\/EHU, BIOMICs Microfluidics Group, Lascaray Research Center, University of the Basque Country UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"}]},{"given":"Tugce","family":"Akyazi","sequence":"additional","affiliation":[{"name":"Microfluidics Cluster UPV\/EHU, Analytical Microsystems &amp; Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"}]},{"given":"Lourdes","family":"Basabe-Desmonts","sequence":"additional","affiliation":[{"name":"Microfluidics Cluster UPV\/EHU, BIOMICs Microfluidics Group, Lascaray Research Center, University of the Basque Country UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"},{"name":"Basque Foundation for Science, IKERBASQUE, 48013 Bilbao, Spain"},{"name":"Bioaraba Health Research Institute, Microfluidics Cluster UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"},{"name":"BCMaterials, Basque Centre for Materials, Micro and Nanodevices, UPV\/EHU Science Park, 48940 Leioa, Spain"}]},{"given":"Fernando","family":"Benito-Lopez","sequence":"additional","affiliation":[{"name":"Microfluidics Cluster UPV\/EHU, Analytical Microsystems &amp; Materials for Lab-on-a-Chip (AMMa-LOAC) Group, Analytical Chemistry Department, University of the Basque Country UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"},{"name":"Bioaraba Health Research Institute, Microfluidics Cluster UPV\/EHU, 01006 Vitoria-Gasteiz, Spain"},{"name":"BCMaterials, Basque Centre for Materials, Micro and Nanodevices, UPV\/EHU Science Park, 48940 Leioa, Spain"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.trac.2017.06.005","article-title":"Paper-based microfluidic analytical devices for colorimetric detection of toxic ions: A review","volume":"93","author":"Sriram","year":"2017","journal-title":"TrACTrends Anal. 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