{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T04:52:59Z","timestamp":1768452779935,"version":"3.49.0"},"reference-count":45,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T00:00:00Z","timestamp":1609200000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>The electromagnetic properties of scroll microcoils are investigated with finite element modelling (FEM) and the design of experiment (DOE) approach. The design of scroll microcoils was optimized for nuclear magnetic resonance (NMR) spectroscopy of nanoliter and subnanoliter sample volumes. The unusual proximity effect favours optimised scroll microcoils with a large number of turns rolled up in close proximity. Scroll microcoils have many advantages over microsolenoids: such as ease of fabrication and better B1-homogeneity for comparable intrinsic signal-to-noise ratio (SNR). Scroll coils are suitable for broadband multinuclei NMR spectroscopy of subnanoliter sample.<\/jats:p>","DOI":"10.3390\/s21010170","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T19:55:25Z","timestamp":1609271725000},"page":"170","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Design of High Performance Scroll Microcoils for Nuclear Magnetic Resonance Spectroscopy of Nanoliter and Subnanoliter Samples"],"prefix":"10.3390","volume":"21","author":[{"given":"Meriam","family":"Khelifa","sequence":"first","affiliation":[{"name":"Environnement M\u00e9diterran\u00e9en et Mod\u00e9lisation des Agro-Hydrosyst\u00e8mes (EMMAH) UMR 1114, Universit\u00e9 d\u2019Avignon et des Pays de Vaucluse, 84018 Avignon, France"},{"name":"Laboratoire d\u2019Acoustique de l\u2019Universit\u00e9 du Mans (LAUM) UMR 6613, Le Mans Universit\u00e9, Avenue Olivier Messiaen, 72085 Le Mans, France"}]},{"given":"Denis","family":"Mounier","sequence":"additional","affiliation":[{"name":"Institut des Mol\u00e9cules et Mat\u00e9riaux du Mans (IMMM) UMR 6283, Le Mans Universit\u00e9, Avenue Olivier Messiaen, 72085 Le Mans, France"}]},{"given":"Nourdin","family":"Yaakoubi","sequence":"additional","affiliation":[{"name":"Laboratoire d\u2019Acoustique de l\u2019Universit\u00e9 du Mans (LAUM) UMR 6613, Le Mans Universit\u00e9, Avenue Olivier Messiaen, 72085 Le Mans, France"}]}],"member":"1968","published-online":{"date-parts":[[2020,12,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1126\/science.270.5244.1967","article-title":"High-Resolution Microcoil 1H-NMR for Mass-Limited, nanoliter Volume samples","volume":"270","author":"Olson","year":"1995","journal-title":"Science"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"3133","DOI":"10.1021\/cr980140f","article-title":"High-Resolution NMR Spectroscopy of Sample Volumes from 1 nL to 10 \u00b5L","volume":"99","author":"Lacey","year":"1999","journal-title":"Chem. 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