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Designing a side-polish D-shaped plane over the PCF\u2019s defect of the periodic air holes can effectively enhance the evanescent field. Graphene on gold can enhance the sensor\u2019s sensitivity because it can stably adsorb biomolecules and increase the propagation constant of the surface plasmon polariton (SPP). Using the finite element method (FEM), we demonstrated that the sensing performance is greatly improved by optimizing the PCF\u2019s geometric structural parameter. The proposed PCF sensor exhibited high performance with a maximum wavelength sensitivity of 4200 nm\/RIU, maximum amplitude sensitivity of 450 RIU\u22121, and refractive index resolution of 2.3 \u00d7 10\u22125 RIU in the sensing range 1.32\u20131.41. This research provides a potential application for the design a new generation of highly sensitive biosensors.<\/jats:p>","DOI":"10.3390\/s21030818","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T08:29:16Z","timestamp":1611649756000},"page":"818","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Highly Sensitive Graphene-Au Coated Plasmon Resonance PCF Sensor"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9272-4329","authenticated-orcid":false,"given":"Hongyan","family":"Yang","sequence":"first","affiliation":[{"name":"School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China"},{"name":"Guangxi Key Laboratory of Automatic Detecting Technology and Instruments, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyin","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1498-2442","authenticated-orcid":false,"given":"Ling","family":"Guo","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Automatic Detecting Technology and Instruments, Guilin University of Electronic Technology, Guilin 541004, China"},{"name":"Guangxi Key Laboratory of Opto-Electronic Information Processing, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gongli","family":"Xiao","sequence":"additional","affiliation":[{"name":"Guangxi Key Laboratory of Precision Navigation Technology and Application, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houquan","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6768-1483","authenticated-orcid":false,"given":"Jianqing","family":"Li","sequence":"additional","affiliation":[{"name":"Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology, Foshan University, Foshan 528225, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libo","family":"Yuan","sequence":"additional","affiliation":[{"name":"School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,1,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/JPHOT.2015.2510632","article-title":"Copper-Graphene-Based Photonic Crystal Fiber Plasmonic Biosensor","volume":"8","author":"Rifat","year":"2015","journal-title":"IEEE Photonics J."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nature01940","article-title":"Photonic Crystal Fibres","volume":"424","author":"Knight","year":"2003","journal-title":"Nature"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5430","DOI":"10.1364\/OL.41.005430","article-title":"Resonant Nanopillars Arrays for Label-Free Biosensing","volume":"41","author":"Casquel","year":"2016","journal-title":"Opt. 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