{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T06:55:00Z","timestamp":1764053700922,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T00:00:00Z","timestamp":1612396800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2020R1A2C2007376","2020M2A8A4023713","2020R1A2C4001606"],"award-info":[{"award-number":["2020R1A2C2007376","2020M2A8A4023713","2020R1A2C4001606"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","award":["HI17C0654"],"award-info":[{"award-number":["HI17C0654"]}],"id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>We propose an integrated front-end data acquisition circuit for a hybrid ultrasound (US)-gamma probe. The proposed circuit consists of three main parts: (1) a preamplifier for the gamma probe, (2) a preprocessing analog circuit for the US, and (3) a digitally controlled analog switch. By exploiting the long idle time of the US system, an analog switch can be used to acquire data of both systems using a single output channel simultaneously. On the nuclear medicine (NM) gamma probe side, energy resolutions of 18.4% and 17.5% were acquired with the standalone system and with the proposed switching circuit, respectively, when irradiated with a Co-57 radiation source. Similarly, signal-to-noise ratios of 14.89 and 13.12 dB were achieved when US echo signals were acquired with the standalone system and with the proposed switching circuit, respectively. Lastly, a combined US-gamma probe was used to scan a glass target and a sealed radiation source placed in a water tank. The results confirmed that, by using a hybrid US-gamma probe system, it is possible to distinguish between the two objects and acquire structural information (ultrasound) alongside molecular information (gamma radiation source).<\/jats:p>","DOI":"10.3390\/s21041048","type":"journal-article","created":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T21:29:27Z","timestamp":1612474167000},"page":"1048","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Simultaneous Acquisition of Ultrasound and Gamma Signals with a Single-Channel Readout"],"prefix":"10.3390","volume":"21","author":[{"given":"Muhammad Nasir","family":"Ullah","sequence":"first","affiliation":[{"name":"Global Health-Tech Research Center, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology, 350-27 Gumi-daero, Gumi 39253, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5015-8357","authenticated-orcid":false,"given":"Yuseung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Interdisciplinary Program in Precision Public Health, Korea University, 145 Anam-ro, Seoul 02841, Korea"}]},{"given":"Gyeong Beom","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Interdisciplinary Program in Precision Public Health, Korea University, 145 Anam-ro, Seoul 02841, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0146-1960","authenticated-orcid":false,"given":"Chanho","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4021-4383","authenticated-orcid":false,"given":"Chansun","family":"Park","sequence":"additional","affiliation":[{"name":"Global Health-Tech Research Center, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"}]},{"given":"Hojong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology, 350-27 Gumi-daero, Gumi 39253, Korea"}]},{"given":"Jung-Yeol","family":"Yeom","sequence":"additional","affiliation":[{"name":"Global Health-Tech Research Center, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Department of Bioengineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"Interdisciplinary Program in Precision Public Health, Korea University, 145 Anam-ro, Seoul 02841, Korea"},{"name":"School of Biomedical Engineering, Korea University, 145 Anam-ro, Seoul 02841, Korea"}]}],"member":"1968","published-online":{"date-parts":[[2021,2,4]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"S26","DOI":"10.1007\/PL00014792","article-title":"Clinical applications of gamma-detection probes\u2014Radioguided surgery","volume":"26","author":"Schneebaum","year":"1999","journal-title":"Eur. 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