{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T23:24:45Z","timestamp":1781825085871,"version":"3.54.5"},"reference-count":40,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["RTC2019-007194-4"],"award-info":[{"award-number":["RTC2019-007194-4"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["RTI2018-094669-B-C31"],"award-info":[{"award-number":["RTI2018-094669-B-C31"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","doi-asserted-by":"publisher","award":["MAT2014-5742 R"],"award-info":[{"award-number":["MAT2014-5742 R"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["IT933-16"],"award-info":[{"award-number":["IT933-16"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["KK-2019\/00101"],"award-info":[{"award-number":["KK-2019\/00101"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003086","name":"Eusko Jaurlaritza","doi-asserted-by":"publisher","award":["KK-2019\/00051"],"award-info":[{"award-number":["KK-2019\/00051"]}],"id":[{"id":"10.13039\/501100003086","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A new approach of Fiber Enhanced Raman Spectroscopy (FERS) is described within this article based on the use of Hydrogel-Core microstructured Polymer Optical Fibers (HyC-mPOF). The incorporation of the hydrogel only on the core of the Hollow-Core microstructured Polymer Optical Fiber (HC-mPOF) enables to perform FERS measurements in a functionalized matrix, enabling high selectivity Raman measurements. The hydrogel formation was continuously monitored and quantified using a Principal Component Analysis verifying the coherence between the components and the Raman spectrum of the hydrogel. The performed measurements with high and low affinity target molecules prove the feasibility of the presented HyC-mPOF platform.<\/jats:p>","DOI":"10.3390\/s21051845","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T21:52:15Z","timestamp":1615153935000},"page":"1845","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Hydrogel-Core Microstructured Polymer Optical Fibers for Selective Fiber Enhanced Raman Spectroscopy"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7222-0043","authenticated-orcid":false,"given":"Mikel","family":"Azkune","sequence":"first","affiliation":[{"name":"Department of Electronic Technology, Engineering School of Bilbao, University of the Basque Country (UPV\/EHU), Torres Quevedo 1, 48013 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1520-7640","authenticated-orcid":false,"given":"Igor","family":"Ayesta","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics, Engineering School of Bilbao, University of the Basque Country (UPV\/EHU), Torres Quevedo 1, 48013 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2045-008X","authenticated-orcid":false,"given":"Leire","family":"Ruiz-Rubio","sequence":"additional","affiliation":[{"name":"Macromolecular Chemistry Research Group (LQM), Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV\/EHU), Barrio Sarriena s\/n, 48940 Leioa, Spain"},{"name":"BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV\/EHU Science Park, 48940 Leioa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7409-6760","authenticated-orcid":false,"given":"Eneko","family":"Arrospide","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics, Engineering School of Bilbao, University of the Basque Country (UPV\/EHU), Torres Quevedo 1, 48013 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0188-4579","authenticated-orcid":false,"given":"Jose Luis","family":"Vilas-Vilela","sequence":"additional","affiliation":[{"name":"Macromolecular Chemistry Research Group (LQM), Department of Physical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV\/EHU), Barrio Sarriena s\/n, 48940 Leioa, Spain"},{"name":"BCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV\/EHU Science Park, 48940 Leioa, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9137-1733","authenticated-orcid":false,"given":"Joseba","family":"Zubia","sequence":"additional","affiliation":[{"name":"Department of Communications Engineering, Engineering School of Bilbao, University of the Basque Country (UPV\/EHU), Plaza Ingeniero Torres Quevedo, 1, 48013 Bilbao, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jobcr.2015.12.002","article-title":"Biosensors and their applications\u2014A review","volume":"6","author":"Mehrotra","year":"2016","journal-title":"J. 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