{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:21:49Z","timestamp":1771572109628,"version":"3.50.1"},"reference-count":35,"publisher":"MDPI AG","issue":"10","license":[{"start":{"date-parts":[[2021,5,15]],"date-time":"2021-05-15T00:00:00Z","timestamp":1621036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2218-E-239-002-MY2"],"award-info":[{"award-number":["108-2218-E-239-002-MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>A dual liquid-crystal variable retarder Mueller polarimetry system incorporating a gold-based surface plasmon resonance prism coupler was proposed for extracting the optical properties of serum albumin protein media in the reflectance configuration. The feasibility of the proposed system was demonstrated by measuring the circular dichroism and circular birefringence properties of glucose tissue phantom solutions with different albumin concentrations. The results showed that the circular dichroism increased with albumin concentration, while the optical rotation angle increased with glucose concentration. Both properties reduced over time as a result of the protein glycation effect, which led to a gradual reduction in the glucose content of the sample.<\/jats:p>","DOI":"10.3390\/s21103442","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T02:31:34Z","timestamp":1621218694000},"page":"3442","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Dual-Retarder Mueller Polarimetry System for Extraction of Optical Properties of Serum Albumin Protein Media"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5150-1890","authenticated-orcid":false,"given":"Quoc-Hung","family":"Phan","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, National United University, Miaoli 36063, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Yuan","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Electro-Optical Engineering, National United University, Miaoli 36063, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Hsiang","family":"Lien","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, National United University, Miaoli 36063, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5808-3214","authenticated-orcid":false,"given":"Thi-Thu-Hien","family":"Pham","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, International University, Ho Chi Minh City 700000, Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,5,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.diabres.2011.10.040","article-title":"The international diabetes federation diabetes atlas methodology for estimating global and national prevalence of diabetes in adults","volume":"94","author":"Guariguata","year":"2011","journal-title":"Diab. Res. Clin. Pract."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1109\/10.649993","article-title":"Noninvasive glucose sensing utilizing a digital closed-loop polarimetric approach","volume":"44","author":"Cameron","year":"1997","journal-title":"IEEE Trans. Biomed. Eng."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s11468-012-9415-8","article-title":"A new route to glucose sensing based on surface plasmon resonance using polyindole","volume":"8","author":"Kumar","year":"2013","journal-title":"Plasmonics"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Neilsen, S.M.L., Pors, A., Banke, S.O., Henriksen, J.E., Hepp, D.K., and Weber, A. (2018). Critical depth Raman spectroscopy enables home use noninvasive glucose monitoring. 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Care."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"18828","DOI":"10.3390\/molecules191118828","article-title":"Kinetics of glycoxidation of bovine serum albumin by glucose, fructose and ribose and its prevention by food components","volume":"19","author":"Galiniak","year":"2014","journal-title":"Molecules"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"4880","DOI":"10.3390\/molecules19044880","article-title":"Kinetics of glycoxidation of bovine serum albumin by methylglyoxal and glyoxal and its prevention by various compunds","volume":"19","author":"Bartosz","year":"2014","journal-title":"Molecules"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"6340","DOI":"10.1364\/BOE.10.006340","article-title":"Broadband polarimetric glucose determination in protein containing media using characteristic optical rotatory dispersion","volume":"10","author":"Stark","year":"2019","journal-title":"Biomed. Opt. Express"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0003-2670(98)00318-3","article-title":"Measurement of glucose and other analytes in undiluted human serum with nearinfrared transmission spectroscopy","volume":"371","author":"Hazen","year":"1998","journal-title":"Anal. Chim. Acta"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1364\/OL.39.003149","article-title":"Uniquenes of the differential Mueller matrix of uniform homogenous media","volume":"39","author":"Devlaminck","year":"2019","journal-title":"Opt. Lett."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1250017","DOI":"10.1142\/S1793545812500174","article-title":"Quantitative Mueller matrix polarimetry techniques for biological tissues","volume":"5","author":"He","year":"2012","journal-title":"J. Innov. Opt. Health Sci."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1364\/AO.49.003458","article-title":"Mueller matrix measurement on absorbing turbid media","volume":"49","author":"Swami","year":"2010","journal-title":"Appl. Opt."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.optlaseng.2016.08.017","article-title":"Stokes-Mueller matrix polarimetry system for glucose sensing","volume":"92","author":"Phan","year":"2017","journal-title":"Opt. Laser. Eng."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1364\/JOSAA.13.001106","article-title":"Interpretation of Mueller matrices based on polar decomposition","volume":"13","author":"Lu","year":"1996","journal-title":"J. Opt. Soc. Am. A"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"4048","DOI":"10.1364\/OL.42.004048","article-title":"Extended polar decomposition method of Mueller matrices for turbid media in reflection geometry","volume":"42","author":"Qi","year":"2017","journal-title":"Opt. Lett."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1364\/AO.57.004353","article-title":"Optical parameters of human blood plasma, collagen, and calfskin based on the Stokes Mueller technique","volume":"57","author":"Pham","year":"2018","journal-title":"Appl. Opt."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1364\/JOSA.68.001756","article-title":"Propagation of partially polarized light through anisotropic media with or without depolarization: A differential 4 \u00d7 4 matrix calculus","volume":"68","author":"Azzam","year":"1978","journal-title":"J. Opt. Soc. Am."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1364\/OL.36.001942","article-title":"Mueller matrix differential decomposition","volume":"36","author":"Quijano","year":"2011","journal-title":"Opt. Lett."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"14348","DOI":"10.1364\/OE.19.014348","article-title":"Mueller matrix differential decomposition for direction reversal: Application to samples measures in reflection and backscattering","volume":"19","author":"Quijano","year":"2011","journal-title":"Opt. Express"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"16831","DOI":"10.1364\/OE.21.016831","article-title":"Extraction of anisotropic parameters of turbid media using hybrid model comprising differential and decomposition-based Mueller matrices","volume":"21","author":"Liao","year":"2013","journal-title":"Opt. Express"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1364\/JOSAA.33.001396","article-title":"Stokes vector and Muller matrix polarimetry","volume":"33","author":"Azzam","year":"2016","journal-title":"J. Opt. Soc. Am. A"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"6805","DOI":"10.1364\/AO.51.006805","article-title":"Mueller matrix polarimetry with four photoelastic modulators: Theory and calibration","volume":"51","author":"Arteaga","year":"2012","journal-title":"Appl. Opt."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"15179","DOI":"10.1364\/OE.25.015179","article-title":"Differential Mueller matrix polarimetry technique for noninvasive measurement of glucose concentration on human fingertip","volume":"25","author":"Phan","year":"2017","journal-title":"Opt. Express"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"15851","DOI":"10.1364\/OE.26.015851","article-title":"Evaluation of structural and molecular variation of starch granules during the gelatinization process by using the rapid Mueller matrix imaging polarimetry system","volume":"26","author":"Han","year":"2018","journal-title":"Opt. Express"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"014009","DOI":"10.1116\/1.5122749","article-title":"Nonideal optical response of liquid crystal variable retarder and its impact on their performance as polarization modulators","volume":"38","author":"Parejo","year":"2020","journal-title":"J. Vac. Sci. Technol. B"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1364\/OL.28.000616","article-title":"Optimized Mueller polarimeter with liquid crystal","volume":"28","author":"Martino","year":"2003","journal-title":"Opt. Lett."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1364\/AO.43.002824","article-title":"Mueller polarimetric imaging system with liquid crystal","volume":"43","author":"Boulesteix","year":"2004","journal-title":"Appl. Opt."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.optcom.2016.08.026","article-title":"Rapid full Mueller matrix imaging polarimetry based on the hybrid phase modulation technique","volume":"382","author":"Han","year":"2017","journal-title":"Opt. Commun."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"24889","DOI":"10.1364\/OE.400721","article-title":"Surface plasmon resonance prism coupler for enhanced circular birefringence sensing and application to noninvasive glucose detection","volume":"28","author":"Phan","year":"2020","journal-title":"Opt. Express"},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"106268","DOI":"10.1016\/j.optlaseng.2020.106268","article-title":"Combination of surface plasmon esonance and differential Mueller matrix formalism for noninvasive glucose sensing","volume":"134","author":"Phan","year":"2020","journal-title":"Opt. Laser. Eng."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"061507","DOI":"10.1117\/1.JNP.6.061507","article-title":"Use of Ta2O5 biaxial thin films as a high efficiency polarization converter","volume":"6","author":"Lin","year":"2012","journal-title":"J. Nanophotonics"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1364\/OL.36.002330","article-title":"Differential matrix formalism for depolarizing anisotropic media","volume":"36","author":"Ossikovski","year":"2011","journal-title":"Opt. Lett."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1117\/1.1626664","article-title":"New optical scheme for a polarimetric based glucose sensor","volume":"9","author":"Ansari","year":"2004","journal-title":"J. Biomed. 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