{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:56:35Z","timestamp":1760784995610,"version":"build-2065373602"},"reference-count":23,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T00:00:00Z","timestamp":1631145600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Micro-cantilever sensors are a known reliable tool for gas sensing in industrial applications. We have demonstrated the application of cantilever sensors on the detection of a meat freshness volatile biomarker (cadaverine), for determination of meat and fish precise expiration dates. For achieving correct target selectivity, the cantilevers need to be functionalized with a cadaverine-selective binder, based on a cyclam-derivative. Cantilever surface properties such as surface energy strongly influence the binder morphology and material clustering and, therefore, target binding. In this paper, we explore how chemical and physical surface treatments influence cantilever surface, binder morphology\/clustering and binding capabilities. Sensor measurements with non-controlled surface properties are presented, followed by investigations on the binder morphology versus surface energy and cadaverine capture. We demonstrated a method for hindering binder crystallization on functionalized surfaces, leading to reproducible target capture. The results show that cantilever surface treatment is a promising method for achieving a high degree of functionalization reproducibility for industrial cantilever sensors, by controlling binder morphology and uniformity.<\/jats:p>","DOI":"10.3390\/s21186041","type":"journal-article","created":{"date-parts":[[2021,9,9]],"date-time":"2021-09-09T21:36:58Z","timestamp":1631223418000},"page":"6041","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Surface Modification Enabling Reproducible Cantilever Functionalization for Industrial Gas Sensors"],"prefix":"10.3390","volume":"21","author":[{"given":"Daniel","family":"Mamou","sequence":"first","affiliation":[{"name":"NanoSYD Center, Mads Clausen Institute, University of Southern Denmark, 6400 S\u00f8nderborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5939-9528","authenticated-orcid":false,"given":"Lawrence","family":"Nsubuga","sequence":"additional","affiliation":[{"name":"NanoSYD Center, Mads Clausen Institute, University of Southern Denmark, 6400 S\u00f8nderborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Lisboa Marcondes","sequence":"additional","affiliation":[{"name":"NanoSYD Center, Mads Clausen Institute, University of Southern Denmark, 6400 S\u00f8nderborg, Denmark"},{"name":"AmiNIC ApS, 5500 Middelfart, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2421-1550","authenticated-orcid":false,"given":"Simon Overgaard","family":"H\u00f8egh","sequence":"additional","affiliation":[{"name":"AmiNIC ApS, 5500 Middelfart, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette","family":"Hvam","sequence":"additional","affiliation":[{"name":"AmiNIC ApS, 5500 Middelfart, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Niekiel","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Silicon Technology, 25524 Itzehoe, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Lofink","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Silicon Technology, 25524 Itzehoe, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3606-5653","authenticated-orcid":false,"given":"Horst-G\u00fcnter","family":"Rubahn","sequence":"additional","affiliation":[{"name":"NanoSYD Center, Mads Clausen Institute, University of Southern Denmark, 6400 S\u00f8nderborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5694-2820","authenticated-orcid":false,"given":"Roana","family":"de Oliveira Hansen","sequence":"additional","affiliation":[{"name":"NanoSYD Center, Mads Clausen Institute, University of Southern Denmark, 6400 S\u00f8nderborg, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,9]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"036101","DOI":"10.1088\/0034-4885\/74\/3\/036101","article-title":"Cantilever-like micromechanical sensors","volume":"74","author":"Boisen","year":"2011","journal-title":"Rep. 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