{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T10:41:03Z","timestamp":1769078463015,"version":"3.49.0"},"reference-count":41,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["108-2634-F-367-001"],"award-info":[{"award-number":["108-2634-F-367-001"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Education","award":["13001090182-EDU"],"award-info":[{"award-number":["13001090182-EDU"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>As the proportion of elderly people continues to grow, so does the concern about age-related cognitive decline. Serious games have been developed for cognitive training or treatment, but measuring the activity of the autonomic nervous system (ANS) has not been taken to account. However, cognitive functioning has been known to be heavily influenced by the autonomic nervous system (ANS), and ANS activity can be quantified using heart rate variability (HRV). This paper aims to analyze the physiological response in normal elderly people as they play two types of serious games using HRV features from electrocardiography (ECG). A wearable device designed in-house was used to measure ECG, and the data from this device was pre-processed using digital signal processing techniques. Ten HRV features were extracted, including time-domain, nonlinear, and frequency-domain features. The experiment proceeds as follows: rest for three minutes, play a cognitive aptitude game, rest for another three minutes, followed by two reaction time games. Data from thirty older adults (age: 65.9 \u00b1 7.34; male: 15, female: 15) were analyzed. The statistical results show that there was a significant difference in the HRV between the two types of games. From this, it can be concluded that the type of game has a significant effect on the ANS response. This can be further used in designing games for the elderly, either for training or mood management.<\/jats:p>","DOI":"10.3390\/s21196549","type":"journal-article","created":{"date-parts":[[2021,10,8]],"date-time":"2021-10-08T21:26:20Z","timestamp":1633728380000},"page":"6549","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Analysis of Heart Rate Variability in Response to Serious Games in Elderly People"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0268-4392","authenticated-orcid":false,"given":"Chun-Ju","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan City 710301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Ting","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan City 710301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mycel","family":"Capilayan","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan City 710301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Sian","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan City 710301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min-Wei","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi 000600, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6604-8064","authenticated-orcid":false,"given":"Ji-Jer","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan City 710301, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2021,9,30]]},"reference":[{"key":"ref_1","unstructured":"United Nations (2021, July 03). 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