{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:33:50Z","timestamp":1781642030227,"version":"3.54.5"},"reference-count":118,"publisher":"MDPI AG","issue":"22","license":[{"start":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T00:00:00Z","timestamp":1636848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Phenolic compounds are particularly dangerous due to their ability to remain in the environment for a long period of time and their toxic effects. They enter in the environment in different ways, such as waste from paper manufacturing, agriculture (pesticides, insecticides, herbicides), pharmaceuticals, the petrochemical industry, and coal processing. Conventional methods for phenolic compounds detection present some disadvantages, such as cumbersome sample preparation, complex and time-consuming procedures, and need of expensive equipment. Therefore, there is a very large interest in developing sensors and new sensing schemes for fast and easy-to-use methods for detecting and monitoring the phenolic compound concentration in the environment, with special attention to water. Good analytical properties, reliability, and adaptability are required for the developed sensors. The present paper aims at revising the most generally used optical methods for designing and fabricating biosensors and sensors for phenolic compounds. Some selected examples of the most interesting applications of these techniques are also proposed.<\/jats:p>","DOI":"10.3390\/s21227563","type":"journal-article","created":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T20:51:53Z","timestamp":1636923113000},"page":"7563","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Advanced Optical Sensing of Phenolic Compounds for Environmental Applications"],"prefix":"10.3390","volume":"21","author":[{"given":"Ines","family":"Delfino","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Ecologiche e Biologiche, Universit\u00e0 della Tuscia, I-01100 Viterbo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Diano","sequence":"additional","affiliation":[{"name":"Dipartimento di Medicina Sperimentale, Universit\u00e0 della Campania \u201cLuigi Vanvitelli\u201d, I-80138 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2743-5904","authenticated-orcid":false,"given":"Maria","family":"Lepore","sequence":"additional","affiliation":[{"name":"Dipartimento di Medicina Sperimentale, Universit\u00e0 della Campania \u201cLuigi Vanvitelli\u201d, I-80138 Napoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,11,14]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"Phenolic compounds contaminants in water: A glance","volume":"4","author":"Mainali","year":"2020","journal-title":"Curr. Trends Civ. Struct. Eng."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.jhazmat.2013.12.006","article-title":"Spectrophotometric analysis of phenols, which involves a hemin\u2013graphene hybrid nanoparticles with peroxidase-like activity","volume":"266","author":"Sun","year":"2014","journal-title":"J. Hazard. Mater."},{"key":"ref_3","unstructured":"(2021, November 02). Appendix A to 40 CFR, Part 423\u2013126 Priority Pollutants. U.S. Environmental Protection Agency, Available online: https:\/\/www3.epa.gov\/region1\/npdes\/permits\/generic\/prioritypollutants.pdf."},{"key":"ref_4","unstructured":"(2021, November 02). Priority Substances and Certain Other Pollutants according to Annex II of Directive 2008\/105\/EC. European Commission. Available online: http:\/\/data.europa.eu\/eli\/dir\/2008\/105\/oj."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2722","DOI":"10.1016\/j.phytochem.2007.06.012","article-title":"Evolution and current status of research in phenolic compounds: Review","volume":"68","author":"Boudet","year":"2007","journal-title":"Phytochem"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.54987\/jemat.v2i1.89","article-title":"Phenol and its toxicity","volume":"2","author":"Gami","year":"2014","journal-title":"J. Environ. Microbiol. Toxicol."},{"key":"ref_7","first-page":"347","article-title":"Phenols-sources and toxicity: Review","volume":"16","author":"Michalowicz","year":"2007","journal-title":"Pol. J. Environ. Stud."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1007\/s10661-012-2732-8","article-title":"Toxicological effect of major environmental pollutants: An overview","volume":"185","author":"Wasi","year":"2013","journal-title":"Environ. Monit. Assess."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1365-2826.2011.02229.x","article-title":"Endocrine disrupters: A review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems","volume":"24","author":"Frye","year":"2012","journal-title":"J. Neuroendocrinol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jsbmb.2011.08.007","article-title":"Endocrine disrupting chemicals and disease susceptibility","volume":"127","author":"Schug","year":"2011","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.tox.2006.06.009","article-title":"Human exposure to bisphenol A","volume":"226","author":"Kang","year":"2006","journal-title":"Reprod. Toxicol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.reprotox.2007.07.010","article-title":"Human exposure to bisphenol A (BPA)","volume":"24","author":"Vandenberg","year":"2007","journal-title":"Reprod. Toxicol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1289\/ehp.7534","article-title":"Urinary concentrations of bisphenol A and 4-Nonylphenol in a human reference population","volume":"113","author":"Calafat","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1289\/ehp.10753","article-title":"Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003\u20132004","volume":"116","author":"Calafat","year":"2008","journal-title":"Environ. Health Perspect."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.taap.2007.12.008","article-title":"Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures","volume":"228","author":"Dekant","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s11157-012-9268-9","article-title":"Recent advances in the development of biosensor for phenol: A review","volume":"11","author":"Karim","year":"2012","journal-title":"Rev. Environ. Sci. Biotechnol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1134\/S1061934813110130","article-title":"Optical sensors for determining phenolic compounds with different structures","volume":"68","author":"Rodionov","year":"2013","journal-title":"J. Anal. Chem."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Portaccio, M., Menale, C., Diano, N., Serri, C., Mita, D.G., and Lepore, M. (2015). Monitoring production process of Cisplatin-loaded PLGA nanoparticles by FT-IR microspectroscopy and univariate data analysis. J. Appl. Polym. Sci., 132.","DOI":"10.1002\/app.41305"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Camerlingo, C., Portaccio, M., Tat\u00e8, R., Lepore, M., and Delfino, I. (2017). Fructose and pectin detection in fruit-based food products by surface-enhanced Raman spectroscopy. Sensors, 17.","DOI":"10.3390\/s17040839"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Ricciardi, V., Portaccio, M., Piccolella, S., Manti, L., Pacifico, S., and Lepore, M. (2017). Study of SH-SY5Y cancer cell response to treatment with polyphenol extracts using FT-IR spectroscopy. Biosensors, 7.","DOI":"10.3390\/bios7040057"},{"key":"ref_21","doi-asserted-by":"crossref","unstructured":"Camerlingo, C., Verde, A., Manti, L., Meschini, R., Delfino, I., and Lepore, M. (2018). Graphene-based Raman spectroscopy for pH sensing of X-rays exposed and unexposed culture media and cells. Sensors, 18.","DOI":"10.3390\/s18072242"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1515\/nanoph-2020-0103","article-title":"Pixeled metasurface for multiwavelength detection of vitamin D","volume":"9","author":"Crescitelli","year":"2020","journal-title":"Nanophotonics"},{"key":"ref_23","first-page":"6937489","article-title":"Detection of phenols from industrial effluents using streptomyces mediated gold nanoparticles","volume":"2016","author":"Mazhari","year":"2016","journal-title":"Indian J. Mat. Sci."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"5948","DOI":"10.1109\/JSEN.2018.2843794","article-title":"Colorimetric bisphenol-A detection with a portable smartphone-based spectrometer","volume":"18","author":"Bayram","year":"2018","journal-title":"IEEE Sens. J."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.snb.2008.11.011","article-title":"An optical fibre reflectance sensor for p-aminophenol determination based on tetrahydroxycalix[4]arene as sensing reagent","volume":"136","author":"Filik","year":"2009","journal-title":"Sens. Actuat. B"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jcis.2011.07.028","article-title":"Introduction of a planar defect in a molecularly imprinted photonic crystal sensor for the detection of bisphenol A","volume":"364","author":"Griffete","year":"2011","journal-title":"J. Colloid Interface Sci."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Santos, J.L., and Farahi, F. (2014). Optical Waveguide Sensors. Handbook of Optical Sensors, CRC Press.","DOI":"10.1201\/b17641"},{"key":"ref_28","doi-asserted-by":"crossref","unstructured":"Krohn, D.A., MacDougall, T., and Mendez, A. (2014). Fiber Optic Sensors: Fundamentals and Applications, SPIE Press.","DOI":"10.1117\/3.1002910"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"19885","DOI":"10.1364\/OE.26.019885","article-title":"Surface sensing with integrated optical waveguides: A design guideline","volume":"26","author":"Milvich","year":"2018","journal-title":"Opt. Express"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Del Villar, I., and Matias, I.R. (2020). Optical Fibre Sensors: Fundamentals for Development of Optimized Devices, Wiley-IEEE Press.","DOI":"10.1002\/9781119534730"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"106508","DOI":"10.1016\/j.optlaseng.2020.106508","article-title":"Fiber optic shape sensors: A comprehensive review","volume":"139","author":"Floris","year":"2021","journal-title":"Opt. Lasers Eng."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"25208","DOI":"10.3390\/s151025208","article-title":"Fiber-optic chemical sensors and fiber-optic biosensors","volume":"15","year":"2015","journal-title":"Sensors"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1021\/acs.analchem.9b04708","article-title":"Fiber-optic chemical sensors and biosensors (2015\u20132019)","volume":"92","author":"Wang","year":"2020","journal-title":"Anal. Chem."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1109\/JLT.2017.2756095","article-title":"Exploring the use of native spider silk as an optical fiber for chemical sensing","volume":"36","author":"Tow","year":"2018","journal-title":"J. Lightwave Technol."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Campanella, C.E., Cuccovillo, A., Campanella, C., Yurt, A., and Passaro, V.M.N. (2018). Fibre bragg grating based strain sensors: Review of Technology and Applications. Sensors, 18.","DOI":"10.3390\/s18093115"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"156863","DOI":"10.1109\/ACCESS.2020.3019138","article-title":"Fiber Bragg gratings for medical applications and future challenges: A Review","volume":"8","year":"2020","journal-title":"IEEE Access"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1016\/j.snb.2018.07.092","article-title":"Optic fiber with Er3+: YAlO3\/SiO2\/TiO2 coating and polymer membrane for selective detection of phenol in water","volume":"273","author":"Zhong","year":"2018","journal-title":"Sens. Actuators B Chem."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1039\/C8LC00317C","article-title":"Photochemical device for selective detection of phenol in aqueous solutions","volume":"18","author":"Zhong","year":"2018","journal-title":"Lab Chip"},{"key":"ref_39","first-page":"4191","article-title":"Recent advances in surface plasmon resonance optical sensors for potential application in environmental monitoring","volume":"32","author":"Daniyal","year":"2020","journal-title":"Sens. Mater."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"e06321","DOI":"10.1016\/j.heliyon.2021.e06321","article-title":"Recent progress in surface plasmon resonance-based sensors: A comprehensive review","volume":"7","author":"Yesudasu","year":"2021","journal-title":"Heliyon"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/1-4020-4611-1_7","article-title":"Vibrational spectroscopic sensors fundamentals, instrumentation and applications","volume":"224","author":"Baldini","year":"2006","journal-title":"Optical Chemical Sensor"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1038\/nprot.2014.110","article-title":"Using fourier transform IR spectroscopy to analyze biological materials","volume":"9","author":"Baker","year":"2014","journal-title":"Nat. Protoc."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/nprot.2016.036","article-title":"Using raman spectroscopy to characterize biological materials","volume":"11","author":"Butler","year":"2016","journal-title":"Nat. Protoc."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"5110","DOI":"10.1021\/acs.chemrev.6b00743","article-title":"Surface-Enhanced infrared spectroscopy using resonant nanoantennas","volume":"117","author":"Neubrech","year":"2017","journal-title":"Chem. Rev."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.snb.2019.02.014","article-title":"Metasurface based on cross-shaped plasmonic nanoantennas as chemical sensor for surface-enhanced infrared absorption spectroscopy","volume":"286","author":"Caporale","year":"2019","journal-title":"Sens. Actuators B Chem."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Deepak, F. (2018). Surface-enhanced raman spectroscopy: Principles, substrates, and applications. Metal Nanoparticles and Clusters, Springer.","DOI":"10.1007\/978-3-319-68053-8"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1021\/cr068105t","article-title":"Optical biosensors","volume":"108","author":"Borisov","year":"2008","journal-title":"Chem. Rev."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"631","DOI":"10.13005\/ojc\/340204","article-title":"Laccase biosensor: Green technique for quantification of phenols in wastewater (A review)","volume":"34","author":"Yashas","year":"2018","journal-title":"Orient. J. Chem."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.micron.2003.10.029","article-title":"Laccases: Structure, reactions, distribution","volume":"35","author":"Claus","year":"2004","journal-title":"Micron"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1016\/j.ccr.2005.04.021","article-title":"Investigating the structure and function of cupredoxins","volume":"249","author":"Dennison","year":"2005","journal-title":"Coord. Chem. Rev."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s12934-019-1248-0","article-title":"Laccases: Structure, function, and potential application in water bioremediation","volume":"8","author":"Arregui","year":"2019","journal-title":"Microb. Cell. Fact."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.trac.2015.05.008","article-title":"Laccase-based biosensors for detection of phenolic compounds","volume":"74","author":"Parra","year":"2015","journal-title":"Trends Anal. Chem."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.3390\/s7102238","article-title":"An optical biosensor based on immobilization of laccase and MBTH in stacked films for the detection of catechol","volume":"7","author":"Abdullah","year":"2007","journal-title":"Sensors"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00216-012-6061-0","article-title":"Autoindicating optical properties of laccase as the base of an optical biosensor film for phenol determination","volume":"404","author":"Sanz","year":"2012","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.aca.2011.11.049","article-title":"Determination of polyphenolic content in beverages using laccase, gold nanoparticles and long wavelength fluorimetry","volume":"713","year":"2012","journal-title":"Anal. Chim. Acta"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1002\/bit.10576","article-title":"Determination of laccase activity in mixed solvents: Comparison between two chromogens in a spectrophotometric assay","volume":"82","author":"Cantarella","year":"2003","journal-title":"Biotechnol. Bioeng."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"7608","DOI":"10.1021\/bi952971a","article-title":"Oxidation of phenols, anilines, and benzenethiols by fungal laccases:\u2009 Correlation between activity and redox potentials as well as halide inhibition","volume":"35","author":"Xu","year":"1996","journal-title":"Biochemistry"},{"key":"ref_58","doi-asserted-by":"crossref","unstructured":"Delfino, I., Portaccio, M., Della Ventura, B., Manzo, G., Mita, D.G., and Lepore, M. (2012). Optical properties of sol-gel immobilized Laccase: A first step for its use in optical biosensing. Optical Sensing and Detection II, International Society for Optics and Photonics.","DOI":"10.1117\/12.921396"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1002\/bab.1551","article-title":"Optical detection of different phenolic compounds by means of a novel biosensor based on sol-gel immobilized laccase","volume":"64","author":"Lepore","year":"2017","journal-title":"Biotechnol. Appl. Biochem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.electacta.2015.03.044","article-title":"Laccase biosensor based on low temperature co-fired ceramics for the permanent monitoring of water solutions","volume":"165","author":"Malecha","year":"2015","journal-title":"Electrochim. Acta"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"167","DOI":"10.4071\/1551-4897-4.4.167","article-title":"LTCC-based fluidic components for chemical applications","volume":"4","author":"Thelemann","year":"2007","journal-title":"J. Microelectron. Electron. Pack."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1021\/ac902267f","article-title":"Ceramic microsystem incorporating a microreactor with immobilized biocatalyst for enzymatic spectrophotometric assays","volume":"82","author":"Baeza","year":"2010","journal-title":"Anal. Chem."},{"key":"ref_63","doi-asserted-by":"crossref","unstructured":"Cano-Raya, C., Dencheva, N.V., Braz, J.F., Malfois, M., and Denchev, Z.Z. (2020). Optical biosensor for catechol determination based on laccase-immobilized anionic polyamide 6 microparticles. J. Appl. Polym. Sci., 137.","DOI":"10.1002\/app.49131"},{"key":"ref_64","first-page":"72","article-title":"Polyphenol oxidase (PPO) based biosensors for detection of phenolic compounds: A Review","volume":"5","author":"Gul","year":"2017","journal-title":"J. App. Biol. Biotechnol."},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.syapm.2005.07.012","article-title":"Bacterial tyrosinases","volume":"29","author":"Claus","year":"2006","journal-title":"Syst. Appl. Microbiol."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0003-2670(99)00143-9","article-title":"The development of an immobilized enzyme bioprobe for the detection of phenolic pollutants in water","volume":"389","author":"Russell","year":"1999","journal-title":"Anal. Chim. Acta"},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.snb.2005.06.019","article-title":"Immobilization of tyrosinase in chitosan film for an optical detection of phenol","volume":"114","author":"Abdullah","year":"2005","journal-title":"Sens. Actuators B Chem."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1016\/j.bios.2010.01.033","article-title":"Mushroom tyrosinase in polyelectrolyte multilayers as an optical biosensor for o-diphenols","volume":"25","author":"Fiorentino","year":"2010","journal-title":"Biosens. Bioelectron."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"9729","DOI":"10.1021\/ac301110d","article-title":"Colorimetric paper bioassay for the detection of phenolic compounds","volume":"84","author":"Alkasir","year":"2012","journal-title":"Anal. Chem."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1039\/c0an00353k","article-title":"Phenol biosensor based on hydrogel microarrays entrapping tyrosinase and quantum dots","volume":"135","author":"Jang","year":"2010","journal-title":"Analyst"},{"key":"ref_71","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.snb.2013.06.034","article-title":"SPR based fibre optic biosensor for phenolic compounds using immobilization of tyrosinase in polyacrylamide gel","volume":"186","author":"Singh","year":"2013","journal-title":"Sens. Actuators B Chem."},{"key":"ref_72","doi-asserted-by":"crossref","first-page":"164786","DOI":"10.1016\/j.ijleo.2020.164786","article-title":"Structural, optical and potential sensing properties of tyrosinase immobilized graphene oxide thin film on gold surface","volume":"212","author":"Hashim","year":"2020","journal-title":"Optik"},{"key":"ref_73","doi-asserted-by":"crossref","first-page":"9738","DOI":"10.1364\/OE.387027","article-title":"Detection of phenol by incorporation of gold modified-enzyme based graphene oxide thin film with surface plasmon resonance technique","volume":"28","author":"Hashim","year":"2020","journal-title":"Opt. Express"},{"key":"ref_74","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3390\/electrochem2010012","article-title":"Falc\u00e3o, I.R.; da S. Souza, J.E.; Rocha, T.G.; de Sousa, I.G.; Cavalcante, A.L.G.; de Oliveira, A.L.B.; de Sousa, M.C.M.; dos Santos, J.C.S. Designing of nanomaterials-based enzymatic biosensors: Synthesis, properties, and applications","volume":"2","author":"Cavalcante","year":"2021","journal-title":"Electrochem"},{"key":"ref_75","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.snb.2006.09.014","article-title":"Recent advancements in surface plasmon resonance immunosensors for detection of small molecules of biomedical, food and environmental interest","volume":"121","author":"Shankaran","year":"2007","journal-title":"Sens. Actuators B Chem."},{"key":"ref_76","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00216-007-1536-0","article-title":"Multichannel SPR biosensor for detection of endocrine-disrupting compounds","volume":"389","author":"Homola","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_77","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.bios.2013.11.069","article-title":"Highly sensitive and selective optofluidics-based immunosensor for rapid assessment of Bisphenol A leaching risk","volume":"55","author":"Long","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"ref_78","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.envint.2010.04.009","article-title":"Simultaneous determination and assessment of 4-nonylphenol, bisphenol A and triclosan in tap water, bottled water and baby bottles","volume":"36","author":"Li","year":"2010","journal-title":"Environ. Int."},{"key":"ref_79","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0925-4005(98)00176-2","article-title":"The detection of phenols in water using a surface Plasmon resonance system with specific receptors","volume":"51","author":"Wright","year":"1998","journal-title":"Sens. Actuators B Chem."},{"key":"ref_80","doi-asserted-by":"crossref","unstructured":"Conti, L., Mummolo, L., Romano, G.M., Giorgi, C., Giacomazzo, G.E., Prodi, L., and Bencini, A. (2021). Exploring the ability of luminescent metal assemblies to bind and sense anionic or ionizable analytes a Ru(phen)2bipy-based dizinc complex for bisphenol A (BPA) recognition. Molecules, 26.","DOI":"10.3390\/molecules26030527"},{"key":"ref_81","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1039\/C4EM00046C","article-title":"A portable optic fiber aptasensor for sensitive, specific and rapid detection of bisphenol-A in water samples","volume":"16","author":"Yildirim","year":"2014","journal-title":"Environ. Sci. Process Impacts"},{"key":"ref_82","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bios.2017.02.029","article-title":"Detection of bisphenol A using palm-size NanoAptamer analyzer","volume":"94","author":"Lim","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"ref_83","doi-asserted-by":"crossref","first-page":"8873","DOI":"10.1021\/es2013402","article-title":"Gene quantification by the NanoGene assay is resistant to inhibition by humic acids","volume":"45","author":"Kim","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"ref_84","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.bios.2019.02.043","article-title":"An ultra-sensitive aptasensor on optical fibre for the direct detection of bisphenol A","volume":"135","author":"Allsop","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"ref_85","doi-asserted-by":"crossref","unstructured":"Mazhari, B.B.Z., Agsar, D., and Prasad, M.V.N.A. (2017). Development of paper biosensor for the detection of phenol from industrial effluents using bioconjugate of Tyr-AuNps mediated by novel isolate Streptomyces tuirus DBZ39. J. Nanomat., 2017.","DOI":"10.1155\/2017\/1352134"},{"key":"ref_86","doi-asserted-by":"crossref","first-page":"7083","DOI":"10.1021\/la300018t","article-title":"SPR sensing of bisphenol A using molecularly imprinted nanoparticles immobilized on slab optical waveguide with consecutive parallel Au and Ag deposition bands coexistent with bisphenol A-immobilized Au nanoparticles","volume":"28","author":"Taguchi","year":"2012","journal-title":"Langmuir"},{"key":"ref_87","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1007\/s00216-014-7664-4","article-title":"A microvolume molecularly imprinted polymer modified fiber-optic evanescent wave sensor for bisphenol A determination","volume":"406","author":"Xiong","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"ref_88","doi-asserted-by":"crossref","first-page":"111821","DOI":"10.1016\/j.bios.2019.111821","article-title":"Integration of black phosphorus and hollow-core anti-resonant fiber enables two-order magnitude enhancement of sensitivity for bisphenol A detection","volume":"149","author":"Qiao","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"ref_89","doi-asserted-by":"crossref","first-page":"112913","DOI":"10.1016\/j.jpba.2019.112913","article-title":"Advanced sensing technologies of phenolic compounds for pharmaceutical and biomedical analysis","volume":"179","author":"Ge","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref_90","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1021\/cr068102g","article-title":"Optical chemical sensors","volume":"108","author":"McDonagh","year":"2008","journal-title":"Chem. Rev."},{"key":"ref_91","doi-asserted-by":"crossref","first-page":"5003","DOI":"10.1039\/C5CS00103J","article-title":"Development of fluorescent probes based on protection-deprotection of the key functional groups for biological imaging","volume":"44","author":"Tang","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"ref_92","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1021\/acs.analchem.5b04029","article-title":"A highly sensitive and selective fluorescent probe for thiophenol designed via a twist-blockage strategy","volume":"88","author":"Sun","year":"2016","journal-title":"Anal. Chem."},{"key":"ref_93","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.talanta.2019.02.022","article-title":"A dual-response near-infrared fluorescent probe for rapid detecting thiophenol and its application in water samples and bio-imaging","volume":"199","author":"Li","year":"2019","journal-title":"Talanta"},{"key":"ref_94","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1364\/AO.58.002091","article-title":"Photochemical reflective optical fiber sensor for selective detection of phenol in aqueous solutions","volume":"58","author":"Wang","year":"2019","journal-title":"Appl. Opt."},{"key":"ref_95","doi-asserted-by":"crossref","first-page":"4254","DOI":"10.1039\/D0AY01293A","article-title":"Quantum dots as nanosensors for detection of toxics: A literature review","volume":"12","author":"Ganesan","year":"2020","journal-title":"Anal. Methods"},{"key":"ref_96","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.saa.2007.12.003","article-title":"Optical detection of phenolic compounds based on the surface plasmon resonance band of Au nanoparticles","volume":"71","author":"Nezhad","year":"2008","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"ref_97","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.snb.2017.01.165","article-title":"Ultrasensitive bisphenol A sensing based on responsive plasmonic nanoparticles","volume":"245","author":"Ma","year":"2017","journal-title":"Sens. Actuators B Chem."},{"key":"ref_98","doi-asserted-by":"crossref","first-page":"7266","DOI":"10.3390\/s90907266","article-title":"Semiconductor quantum dots in chemical sensors and biosensors","volume":"9","author":"Frasco","year":"2009","journal-title":"Sensors"},{"key":"ref_99","doi-asserted-by":"crossref","unstructured":"Lesiak, A., Drzozga, K., Cabaj, J., Ba\u0144ski, M., Malecha, K., and Podhorodecki, A. (2019). Optical sensors based on II-VI quantum dots. Nanomaterials, 9.","DOI":"10.3390\/nano9020192"},{"key":"ref_100","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1016\/j.bios.2016.01.001","article-title":"Near-infrared fluorescence nanoprobe for enzyme-substrate system sensing and in vitro imaging","volume":"79","author":"Yan","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"ref_101","doi-asserted-by":"crossref","first-page":"11045","DOI":"10.1016\/j.jmrt.2020.07.100","article-title":"Fabrication of CuO nanoparticle: An efficient catalyst utilized for sensing and degradation of Phenol","volume":"9","author":"Nayak","year":"2020","journal-title":"J. Mater. Res. Technol."},{"key":"ref_102","doi-asserted-by":"crossref","first-page":"119019","DOI":"10.1016\/j.saa.2020.119019","article-title":"Facile synthesis of doped CxNy QDs as photoluminescent matrix for direct detection of hydroquinone","volume":"246","author":"Jaiswal","year":"2021","journal-title":"Spectrochim. Acta Part A Mol. Biomol. Spectrosc."},{"key":"ref_103","doi-asserted-by":"crossref","first-page":"6201","DOI":"10.1016\/j.ceramint.2020.10.198","article-title":"ZnO\u2013SnO2 nanocubes for fluorescence sensing and dye degradation applications","volume":"47","author":"Kumar","year":"2021","journal-title":"Ceram. Int."},{"key":"ref_104","doi-asserted-by":"crossref","unstructured":"Ponnusamy, R., Venkatesan, R., Samal, R., Kandasamy, M., Gandhiraj, V., Chakraborty, B., and Rout, C.S. (2021). Bifunctional WO3 microrods decorated RGO composite as catechol sensor and optical limiter. Appl. Surf. Sci., 536.","DOI":"10.1016\/j.apsusc.2020.147669"},{"key":"ref_105","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/lpor.200810034","article-title":"Optical sensing with photonic crystal fibers","volume":"2","author":"Santos","year":"2008","journal-title":"Laser Photon. Rev."},{"key":"ref_106","doi-asserted-by":"crossref","unstructured":"Niger, M., and Hasin, T.F. (2019, January 28\u201330). Detection of harmful chemical compounds in plastics with highly sensitive photonic crystal fiber with higher nonlinear coefficient. Proceedings of the 2019 IEEE International Conference on Signal Processing, Information, Communication & Systems (SPICSCON), Dhaka, Bangladesh.","DOI":"10.1109\/SPICSCON48833.2019.9065165"},{"key":"ref_107","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1366\/0003702844555304","article-title":"Determination of phenols in water using Raman spectroscopy","volume":"380","author":"Marley","year":"1984","journal-title":"Appl. Spectrosc."},{"key":"ref_108","doi-asserted-by":"crossref","first-page":"11614","DOI":"10.1021\/ac502541v","article-title":"Rational design of a bisphenol a aptamer selective surface-enhanced Raman scattering nanoprobe","volume":"86","author":"Marks","year":"2014","journal-title":"Anal. Chem."},{"key":"ref_109","doi-asserted-by":"crossref","first-page":"025008","DOI":"10.1088\/2043-6254\/aa5e22","article-title":"Design and measurement technique of surface-enhanced Raman scattering for detection of bisphenol A","volume":"8","author":"Bakar","year":"2017","journal-title":"Adv. Nat. Sci. Nanosci. Nanotechnol."},{"key":"ref_110","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.talanta.2018.05.001","article-title":"Sensitive detection of bisphenol A by coupling solid phase microextraction based on monolayer graphene-coated Ag nanoparticles on Si fibers to surface enhanced Raman spectroscopy","volume":"187","author":"Qiu","year":"2018","journal-title":"Talanta"},{"key":"ref_111","doi-asserted-by":"crossref","first-page":"5622","DOI":"10.1039\/C8AY01966E","article-title":"A highly sensitive SERS probe for bisphenol A detection based on functionalized Au@Ag nanoparticles","volume":"10","author":"Wang","year":"2018","journal-title":"Anal. Methods"},{"key":"ref_112","doi-asserted-by":"crossref","unstructured":"Roschi, E., Gellini, C., Ricci, M., Sanchez-Cortes, S., Focardi, C., Neri, B., Otero, J.C., L\u00f3pez-Toc\u00f3n, I., Smulevich, G., and Becucci, M. (2021). Surface-enhanced Raman spectroscopy for bisphenols detection: Toward a better understanding of the analyte\u2013nanosystem interactions. Nanomaterials, 11.","DOI":"10.3390\/nano11040881"},{"key":"ref_113","doi-asserted-by":"crossref","first-page":"9299","DOI":"10.1021\/ac101812x","article-title":"Portable surface-enhanced Raman scattering sensor for rapid detection of aniline and phenol derivatives by on-site electrostatic preconcentration","volume":"82","author":"Li","year":"2010","journal-title":"Anal. Chem."},{"key":"ref_114","doi-asserted-by":"crossref","first-page":"8582","DOI":"10.1021\/ac2019766","article-title":"Coupling reaction-based ultrasensitive detection of phenolic estrogens using surface-enhanced resonance Raman scattering","volume":"83","author":"Han","year":"2011","journal-title":"Anal. Chem."},{"key":"ref_115","doi-asserted-by":"crossref","first-page":"455301","DOI":"10.1088\/0957-4484\/27\/45\/455301","article-title":"Highly reproducible surface-enhanced Raman scattering substrate for detection of phenolic pollutants","volume":"27","author":"Zeng","year":"2016","journal-title":"Nanotechnology"},{"key":"ref_116","doi-asserted-by":"crossref","first-page":"13","DOI":"10.25518\/1780-4507.16270","article-title":"Characterization and discrimination of phenolic compounds using Fourier transform Raman spectroscopy and chemometric tools","volume":"22","author":"Pompeu","year":"2018","journal-title":"Biotechnol. Agron. Soc. Environ."},{"key":"ref_117","doi-asserted-by":"crossref","unstructured":"Carreira-Casais, A., Montes-Garc\u00eda, V., Pastoriza-Santos, I., Prieto, M.\u00c1., Simal-Gandara, J., and P\u00e9rez-Juste, J. (2021). Multiple SERS detection of phenol derivatives in tap water. Proceedings, 70.","DOI":"10.3390\/foods_2020-07755"},{"key":"ref_118","doi-asserted-by":"crossref","first-page":"5929","DOI":"10.1021\/acs.analchem.0c00047","article-title":"Surface-enhanced Raman scattering of phenols and catechols by a molecular analogue of titanium dioxide","volume":"92","author":"Liu","year":"2020","journal-title":"Anal. Chem."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/21\/22\/7563\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T07:30:01Z","timestamp":1760167801000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/21\/22\/7563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,14]]},"references-count":118,"journal-issue":{"issue":"22","published-online":{"date-parts":[[2021,11]]}},"alternative-id":["s21227563"],"URL":"https:\/\/doi.org\/10.3390\/s21227563","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,14]]}}}