{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T16:46:36Z","timestamp":1765039596881,"version":"build-2065373602"},"reference-count":25,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T00:00:00Z","timestamp":1639353600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002969","name":"Technology Agency of the Czech Republic","doi-asserted-by":"publisher","award":["TJ02000243"],"award-info":[{"award-number":["TJ02000243"]}],"id":[{"id":"10.13039\/501100002969","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>With the development of light microscopy, it is becoming increasingly easy to obtain detailed multicolor fluorescence volumetric data. The need for their appropriate visualization has become an integral part of fluorescence imaging. Virtual reality (VR) technology provides a new way of visualizing multidimensional image data or models so that the entire 3D structure can be intuitively observed, together with different object features or details on or within the object. With the need for imaging advanced volumetric data, demands for the control of virtual object properties are increasing; this happens especially for multicolor objects obtained by fluorescent microscopy. Existing solutions with universal VR controllers or software-based controllers with the need to define sufficient space for the user to manipulate data in VR are not usable in many practical applications. Therefore, we developed a custom gesture-based VR control system with a custom controller connected to the FluoRender visualization environment. A multitouch sensor disk was used for this purpose. Our control system may be a good choice for easier and more comfortable manipulation of virtual objects and their properties, especially using confocal microscopy, which is the most widely used technique for acquiring volumetric fluorescence data so far.<\/jats:p>","DOI":"10.3390\/s21248329","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T01:22:05Z","timestamp":1639444925000},"page":"8329","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Novel Gesture-Based Control System for Fluorescence Volumetric Data in Virtual Reality"],"prefix":"10.3390","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0441-9840","authenticated-orcid":false,"given":"Vratislav","family":"Cmiel","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering, Brno University of Technology, Technicka 12, 616 00 Brno, Czech Republic"}]},{"given":"Larisa","family":"Chmelikova","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Brno University of Technology, Technicka 12, 616 00 Brno, Czech Republic"}]},{"given":"Inna","family":"Zumberg","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Brno University of Technology, Technicka 12, 616 00 Brno, Czech Republic"}]},{"given":"Martin","family":"Kralik","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Brno University of Technology, Technicka 12, 616 00 Brno, Czech Republic"}]}],"member":"1968","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1364\/OL.19.000780","article-title":"Breaking the diffraction resolution limit by stimulated emission: Stimulated-emission-depletion fluorescence microscopy","volume":"19","author":"Hell","year":"1994","journal-title":"Opt. 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