{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:29:22Z","timestamp":1780536562950,"version":"3.54.1"},"reference-count":44,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T00:00:00Z","timestamp":1644192000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Taiwan's Ministry of Science and Technology","award":["MOST-110-2321-B-010-005"],"award-info":[{"award-number":["MOST-110-2321-B-010-005"]}]},{"name":"Taiwan's Ministry of Science and Technology","award":["MOST-110-2221-E-A49A-504-MY3"],"award-info":[{"award-number":["MOST-110-2221-E-A49A-504-MY3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>Magnetic resonance fingerprinting (MRF) based on echo-planar imaging (EPI) enables whole-brain imaging to rapidly obtain T1 and T2* relaxation time maps. Reconstructing parametric maps from the MRF scanned baselines by the inner-product method is computationally expensive. We aimed to accelerate the reconstruction of parametric maps for MRF-EPI by using a deep learning model. The proposed approach uses a two-stage model that first eliminates noise and then regresses the parametric maps. Parametric maps obtained by dictionary matching were used as a reference and compared with the prediction results of the two-stage model. MRF-EPI scans were collected from 32 subjects. The signal-to-noise ratio increased significantly after the noise removal by the denoising model. For prediction with scans in the testing dataset, the mean absolute percentage errors between the standard and the final two-stage model were 3.1%, 3.2%, and 1.9% for T1, and 2.6%, 2.3%, and 2.8% for T2* in gray matter, white matter, and lesion locations, respectively. Our proposed two-stage deep learning model can effectively remove noise and accurately reconstruct MRF-EPI parametric maps, increasing the speed of reconstruction and reducing the storage space required by dictionaries.<\/jats:p>","DOI":"10.3390\/s22031260","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T20:36:42Z","timestamp":1644266202000},"page":"1260","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Acceleration of Magnetic Resonance Fingerprinting Reconstruction Using Denoising and Self-Attention Pyramidal Convolutional Neural Network"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8066-8841","authenticated-orcid":false,"given":"Jia-Sheng","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Hermann","sequence":"additional","affiliation":[{"name":"Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3405-1394","authenticated-orcid":false,"given":"Frank Gerrit","family":"Z\u00f6llner","sequence":"additional","affiliation":[{"name":"Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lothar R.","family":"Schad","sequence":"additional","affiliation":[{"name":"Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuu-Jiun","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan"},{"name":"College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"},{"name":"Brain Research Center, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Kai","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung-Lin","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chang","sequence":"additional","affiliation":[{"name":"Institute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Te","family":"Wu","sequence":"additional","affiliation":[{"name":"Brain Research Center, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"},{"name":"Institute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1002\/jmri.23718","article-title":"Practical Medical Applications of Quantitative MR Relaxometry","volume":"36","author":"Cheng","year":"2012","journal-title":"J. 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