{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T07:19:50Z","timestamp":1782371990788,"version":"3.54.5"},"reference-count":27,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sensors"],"abstract":"<jats:p>This study aims to introduce a resistance training protocol (6 repetitions \u00d7 70% of 1 maximum repetition (1RM), followed by 6 repetitions \u00d7 50% of 1RM within the same set) specifically designed for postmenopausal women with osteopenia\/osteoporosis and monitor the effect of the protocol on bone mineral density (BMD) in the lumbar spine, assessed by dual-energy X-ray absorptiometry (DEXA). The subjects included in the study were 29 postmenopausal women (56.5 \u00b1 2.8 years) with osteopenia or osteoporosis; they were separated into two groups: the experimental group (n = 15), in which the subjects participated in the strength training protocol for a period of 6 months; and the control group (n = 14), in which the subjects did not take part in any physical activity. BMD in the lumbar spine was measured by DEXA. The measurements were performed at the beginning and end of the study. A statistically significant increase (\u0394% = 1.82%) in BMD was observed at the end of the study for the exercise group (0.778 \u00b1 0.042 at baseline vs. 0.792 \u00b1 0.046 after 6 months, p = 0.018, 95% CI [\u22120.025, \u22120.003]); while an increase was observed for the control group (\u0394% = 0.14%), the difference was not statistically significant (0.762 \u00b1 0.057 at baseline vs. 0.763 \u00b1 0.059, p = 0.85, 95% CI [\u22120.013, 0.011]). In conclusion, our strength training protocol seems to be effective in increasing BMD among women with osteopenia\/osteoporosis and represents an affordable strategy for preventing future bone loss.<\/jats:p>","DOI":"10.3390\/s22051904","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T20:11:57Z","timestamp":1646079117000},"page":"1904","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Effect of Strength Training Protocol on Bone Mineral Density for Postmenopausal Women with Osteopenia\/Osteoporosis Assessed by Dual-Energy X-ray Absorptiometry (DEXA)"],"prefix":"10.3390","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4808-5990","authenticated-orcid":false,"given":"Iulian \u0218tefan","family":"Holubiac","sequence":"first","affiliation":[{"name":"Department of Physical Education and Sport, Stefan cel Mare University, 720229 Suceava, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9976-0397","authenticated-orcid":false,"given":"Florin Valentin","family":"Leuciuc","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, Stefan cel Mare University, 720229 Suceava, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8358-968X","authenticated-orcid":false,"given":"Daniela Maria","family":"Cr\u0103ciun","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport, Stefan cel Mare University, 720229 Suceava, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7397-7969","authenticated-orcid":false,"given":"Tatiana","family":"Dobrescu","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Performance, Vasile Alecsandri University, 600115 Bacau, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/S0001-2998(97)80025-6","article-title":"Technical principles of dual energy x-ray absorptiometry","volume":"27","author":"Blake","year":"1997","journal-title":"Semin. Nucl. Med."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1053\/j.semnuclmed.2010.12.002","article-title":"Bone densitometry","volume":"41","author":"Chun","year":"2011","journal-title":"Semin. Nucl. Med."},{"key":"ref_3","first-page":"10","article-title":"Qualitative Evaluation of Digital Hand X-rays Is Not a Reliable Method to Assess Bone Mineral Density","volume":"5","author":"Miller","year":"2017","journal-title":"Arch. Bone Jt. Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"60","DOI":"10.21037\/qims.2018.01.05","article-title":"Quantitative imaging techniques for the assessment of osteoporosis and sarcopenia","volume":"8","author":"Guerri","year":"2018","journal-title":"Quant. Imaging Med. Surg."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.afos.2019.09.005","article-title":"Nonpharmacological interventions for osteoporosis treatment: Systematic review of clinical practice guidelines","volume":"5","year":"2019","journal-title":"Osteoporos. Sarcopenia"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jsams.2016.10.001","article-title":"Exercise and Sports Science Australia (ESSA) position statement on exercise prescription for the prevention and management of osteoporosis","volume":"5","author":"Beck","year":"2017","journal-title":"J. Sci. Med. Sport"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Pellikaan, P., Giarmatzis, G., Sloten, J.V., Verschueren, S., and Jonkers, I. (2018). Ranking of osteogenic potential of physical exercises in postmenopausal women based on femoral neck strains. PLoS ONE, 13.","DOI":"10.1371\/journal.pone.0195463"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00198-016-3868-0","article-title":"Imminent risk of fracture after fracture","volume":"28","author":"Johansson","year":"2017","journal-title":"Osteoporos. Int."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.beem.2014.07.001","article-title":"Monitoring of osteoporosis therapy","volume":"28","author":"Bruyere","year":"2014","journal-title":"Best Pract. Res. Clin. Endocrinol. Metab."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.trsl.2016.09.006","article-title":"Advances in imaging approaches to fracture risk evaluation","volume":"181","author":"Manhard","year":"2017","journal-title":"Transl. Res."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.jhsa.2018.07.006","article-title":"Emerging Technologies in Osteoporosis Diagnosis","volume":"44","author":"Schultz","year":"2019","journal-title":"Hand Surg. Landsc."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/nrendo.2012.217","article-title":"Advances in bone imaging for osteoporosis","volume":"9","author":"Adams","year":"2013","journal-title":"Nat. Rev. Endocrinol."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bjpt.2018.11.011","article-title":"Exercise for the prevention of osteoporosis in postmenopausal women: An evidence-based guide to the optimal prescription","volume":"23","author":"Daly","year":"2019","journal-title":"Braz. J. Phys. Ther."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1259\/0007-1285-24-278-107","article-title":"Bone destruction not demonstrable by radiography","volume":"24","author":"Ardran","year":"1951","journal-title":"Br. J. Radiol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0899-7071(01)00350-3","article-title":"Percutaneous balloon kyphoplasty for the correction of spinal deformity in painful vertebral body compression fractures","volume":"26","year":"2002","journal-title":"Clin. Imaging"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.berh.2009.09.008","article-title":"Quantifying the material and structural determinants of bone strength","volume":"23","author":"Bouxsein","year":"2009","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1007\/s00198-017-3976-5","article-title":"Imminent fracture risk","volume":"28","author":"Roux","year":"2017","journal-title":"Osteoporos. Int."},{"key":"ref_18","first-page":"55","article-title":"Identification and management of osteoporosis in older adults","volume":"45","author":"Eastell","year":"2016","journal-title":"Med. Older Adults"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1007\/s00198-014-2794-2","article-title":"Clinician\u2019s Guide to Prevention and Treatment of Osteoporosis","volume":"25","author":"Cosman","year":"2014","journal-title":"Osteoporos. Int."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s11914-013-0142-7","article-title":"Clinical Imaging of Bone Microarchitecture with HR-pQCT","volume":"11","author":"Nishiyama","year":"2013","journal-title":"Curr. Osteoporos. Rep."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1148\/radiol.12110462","article-title":"Osteoporosis Imaging: State of the Art and Advanced Imaging","volume":"263","author":"Thomas","year":"2012","journal-title":"Radiology"},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s40842-018-0062-7","article-title":"The challenges of diagnosing osteoporosis and the limitations of currently available tools","volume":"4","author":"Choksi","year":"2018","journal-title":"Clin. Diabetes Endocrinol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.1519\/JSC.0b013e318280d4e2","article-title":"Maximal strength training in postmenopausal women with osteoporosis or osteopenia","volume":"27","author":"Mosti","year":"2013","journal-title":"J. Strength Cond. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1080\/09513590903015593","article-title":"Effect of specific exercise training on bone mineral density in women with postmenopausal osteopenia or osteoporosis","volume":"25","author":"Matos","year":"2009","journal-title":"Gynecol. Endocrinol."},{"key":"ref_25","first-page":"193","article-title":"Resistance training versus weight-bearing aquatic exercise: A cross-sectional analysis of bone mineral density in postmenopausal women","volume":"53","author":"Sandor","year":"2013","journal-title":"Rev. Basileira De Reumatol. (Engl. Ed.)"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"427","DOI":"10.3233\/BMR-130402","article-title":"The effects of strengthening and high-impact exercises on bone metabolism and quality of life in postmenopausal women: A randomized controlled trial","volume":"26","author":"Basat","year":"2013","journal-title":"J. Back Musculoskelet. Rehabil."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"849","DOI":"10.3233\/BMR-150604","article-title":"The effects of clinical pilates exercises on bone mineral density, physical performance and quality of life of women with postmenopausal osteoporosis","volume":"28","author":"Angin","year":"2015","journal-title":"J. Back Musculoskelet. Rehabil."}],"container-title":["Sensors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/1424-8220\/22\/5\/1904\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T22:29:45Z","timestamp":1760135385000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/1424-8220\/22\/5\/1904"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":27,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["s22051904"],"URL":"https:\/\/doi.org\/10.3390\/s22051904","relation":{},"ISSN":["1424-8220"],"issn-type":[{"value":"1424-8220","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,28]]}}}